Medical College Of Wisconsin Biophysics Research Institute
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Medical College Of Wisconsin Biophysics Research Institute
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Author :
language : en
Publisher:
Release Date :
Medical College Of Wisconsin Biophysics Research Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Profiles the Biophysics Research Institute at the Medical College of Wisconsin (MCW) in Milwaukee. Describes the Institute's main areas of research in magnetic resonance imaging and spectroscopy (MRI/MRS) and in electron paramagnetic (or spin) resonance (EPR/ESR). Includes a profile of the Institute's current director and describes medical physics and graduate studies, facilities, faculty, and students. Provides pointers to Web sites featuring MCW's Nitric Oxide Club and MacHTTP information.
Free Radical Damage And Its Control
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Author : C.A. Rice-Evans
language : en
Publisher: Elsevier
Release Date : 1994-02-09
Free Radical Damage And Its Control written by C.A. Rice-Evans and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-09 with Science categories.
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Nitric Oxide
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Author : Lester Packer
language : en
Publisher: Gulf Professional Publishing
Release Date : 1999
Nitric Oxide written by Lester Packer and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Antioxidants categories.
General Description of the Volume: Nitric Oxide, recently designated "Molecule of the Year," impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume will be a valuable resource for the experienced researcher as well as for those newly entering the field. This volume continues the coverage of new and important tools for the elucidation of Nitric Oxide action initiated in Volumes 268 and 269 of Methods in Enzymology. Techniques for researching the physiology and toxicity of nitric oxide in cellular and organismal systems are highlighted. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * Biological Activity * NO Donors: Nitrosothiols and Nitroxyls * Peroxynitrite * Oxidant and Antioxidant Action.
Biomedical Epr Part A Free Radicals Metals Medicine And Physiology
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Author : Sandra S. Eaton
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-20
Biomedical Epr Part A Free Radicals Metals Medicine And Physiology written by Sandra S. Eaton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-20 with Medical categories.
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features: Free Radicals in Medicine Radicals in vivo and in Model Systems, and their Study by Spin Trapping In vivo EPR, including Oximetry and Imaging Time Domain EPR at Radio Frequencies EPR of Copper Complexes: Motion and Frequency Dependence Time Domain EPR and Electron Spin Echo Envelope Modulation
Nitric Oxide Protocols
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Author : M. A Titheradge
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05
Nitric Oxide Protocols written by M. A Titheradge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.
Michael Titheradge provides both the experienced researcher and the newcomer with time-tested techniques to cover all aspects of NO synthase and metabolism. Topics range from the cloning and expression of the different isoforms of NO synthase to the role of NO in DNA damage and apoptosis and include indirect and direct measurements of NO production, measurement on NO synthase mRNA both in situ and in vitro, and Western blotting and immunohistochemical localization of different isoforms of NO synthase. A variety of alternative techniques are described to enable researchers to set up an assay using either the simplest equipment or the most expensive EPR machines.
Biophysical Tools For Biologists
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Author : John J. Correia
language : en
Publisher: Academic Press
Release Date : 2011-09-21
Biophysical Tools For Biologists written by John J. Correia and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-21 with Science categories.
Driven in part by the development of genomics, proteomics, and bioinformatics as new disciplines, there has been a tremendous resurgence of interest in physical methods to investigate macromolecular structure and function in the context of living cells. This volume in Methods in Cell Biology is devoted to biophysical techniques in vitro and their applications to cellular biology. Biophysical Tools for Biologists covers methods-oriented chapters on fundamental as well as cutting-edge techniques in molecular and cellular biophysics. This book is directed toward the broad audience of cell biologists, biophysicists, pharmacologists, and molecular biologists who employ classical and modern biophysical technologies or wish to expand their expertise to include such approaches. It will also interest the biomedical and biotechnology communities for biophysical characterization of drug formulations prior to FDA approval. Describes techniques in the context of important biological problems Delineates critical steps and potential pitfalls for each method Includes full-color plates to illustrate techniques
Nitric Oxide Part G
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Author :
language : en
Publisher: Academic Press
Release Date : 2008-06-26
Nitric Oxide Part G written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-26 with Science categories.
The Nobel Prize was awarded in Physiology or Medicine in 1998 to Louis J. Ignarro, Robert F. Furchgott and Ferid Murad for demonstrating the signaling properties of nitric oxide. Nitric oxide (NO) is one of the few gaseous signaling molecules and is a key biological messenger that plays a role in many biological processes. NO research has led to new treatments for treating heart as well as lung diseases, shock and impotence. (Sildenafil, popularly known by the trade name Viagra, enhances signaling through NO pathways.) Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis.This is another “must-have volume packed with robust methods from authors around the globe. Researchers interested in the detailed biochemistry of NO and its synthesis will have this indispensable volume on their shelves. Essential resource for every laboratory involved in NO-related work Gathers tried and tested techniques from global labs which eliminates searching through many different sources and avoids pitfalls so the same mistakes are not made over and over Aids researchers in the design of medically important therapies for heart disease and cancer
Immunopharmacology Of Free Radical Species
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Author :
language : en
Publisher: Elsevier
Release Date : 1995-05-15
Immunopharmacology Of Free Radical Species written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-05-15 with Medical categories.
Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.
Spin Labeling
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Author : Lawrence Berliner
language : en
Publisher: Springer Science & Business Media
Release Date : 1998-08-31
Spin Labeling written by Lawrence Berliner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-31 with Science categories.
We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. Lastly it is a pleasure to honor two scientists whose contributions were both pioneering and pivotal to the spin label technique: Professor Eduard G. Rozantsev (Moscow), whose synthetic feats in nitroxyl chemistry set the broad stage for a versatile catalog of labels; and Professor Harden M. McConnell, last year's Int- national ESR (EPR) Society Gold Medalist, who conceived and developed the spin label technique to address many biological problems (proteins, enzymes, m- branes, cells, immune response, etc. ). Lawrence J.
Nitric Oxide Part F
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-09-02
Nitric Oxide Part F written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.
The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is a cytotoxic molecule. The physiological and pathological processes of NO production and metabolism and its targets, currently areas of intensive research, have important pharmacologic implications for health and disease.