Membrane Trafficking In Viral Replication
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Membrane Trafficking In Viral Replication
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Author : Mark Marsh
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-10-25
Membrane Trafficking In Viral Replication written by Mark Marsh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-25 with Medical categories.
Viruses are major pathogens in humans, and in the organisms with which we share this planet. The massive health and economic burden these agents impose has spurred a huge research effort to understand their most intimate details. One outcome of this effort has been the production, in many but certainly not all cases, of effective vaccines and therapies. - other consequence has been the realization that we can exploit viruses and put them to work on our behalf. Viruses are still seen to have the most - tential as vehicles for gene delivery and other therapeutic applications. However, their ability to exploit cellular functions to their own ends makes viruses not only highly effective pathogens but also exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. For membrane traffic in parti- lar, viruses have been crucial in providing insights into key cellular fu- tions and the molecular mechanisms underlying these events.
Membrane Trafficking In Viral Replication
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Author : Mark Marsh
language : en
Publisher:
Release Date : 2005
Membrane Trafficking In Viral Replication written by Mark Marsh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Biological transport categories.
The ability of viruses to exploit cellular functions for their own ends makes them highly effective pathogens and exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. Each of the eight chapters in this volume deals with a specific aspect of viral interactions with cellular membranes. These include chapters on viral entry, viral membrane fusion, viral membrane protein synthesis and transport, viral replication, viral interactions with cytoskeletal systems and the nucleus, the trafficking of viral membrane proteins and viral perturbation of host cell protein trafficking. These chapters should provide both an overview of cellular membrane trafficking mechanisms and viral interactions with these systems, as well as reviews of the current state of each of the fields.
Structure Based Study Of Viral Replication
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Author :
language : en
Publisher:
Release Date :
Structure Based Study Of Viral Replication written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Viral Interactions With The Nucleus
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Author : Erin Joanne Walker
language : en
Publisher: Frontiers Media SA
Release Date : 2017-08-16
Viral Interactions With The Nucleus written by Erin Joanne Walker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-16 with Electronic book categories.
Viruses cause numerous medically important diseases, affecting developing, developed, rich and poor alike. The diseases vary in severity, including chickenpox, smallpox, influenza, shingles, herpes, rabies, polio, Ebola, hanta fever, AIDS and the common cold, amongst others. Regardless of the type of tissue or organ affected, all viruses follow the same basic steps to infect host cells. Once in contact with host cells viruses release their genetic material into the cell followed by genome replication, production of viral proteins, assembly of the virus particle and egress from the infected cell. Viruses disrupt normal host cell processes in order to facilitate their own replication/assembly by re-directing cellular machinery for viral transcription, translation, assembly, release and by inhibiting antiviral responses. Regulated nuclear transport of macromolecules through the nuclear pore complex, the only means of transport across the nuclear membrane, is essential for normal cell function and an effective antiviral response. Many viruses disrupt or exploit the nucleocytoplasmic trafficking pathways in host cells. Cytoplasmic viruses exploit the host cell nucleocytoplasmic trafficking machinery to access nuclear functions and/or disrupt nuclear transport, while several DNA viruses use the trafficking pathways to enable export of their components into the cytoplasm; yet others complete their assembly within the nucleus and use nuclear export pathways to access the cytoplasm. Indeed, the many and varied interactions of viruses and viral proteins with nucleocytoplasmic trafficking components have been invaluable in pathway discovery. Importantly, mounting evidence suggests that these interactions play essential roles in virus replication/assembly and hence may be key to understanding pathophysiology of viral diseases. This Frontiers Research Topic is dedicated to the importance of nucleocytoplasmic trafficking to viral pathogenesis.
Scanning Electron Microscopy For The Life Sciences
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Author : Heide Schatten
language : en
Publisher: Cambridge University Press
Release Date : 2013
Scanning Electron Microscopy For The Life Sciences written by Heide Schatten and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Science categories.
A guide to modern scanning electron microscopy instrumentation, methodology and techniques, highlighting novel applications to cell and molecular biology.
Trafficking Inside Cells
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Author : Nava Segev
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-30
Trafficking Inside Cells written by Nava Segev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-30 with Science categories.
This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
Molecular Regulation Of Endocytosis
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Author : Brian Ceresa
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-07-06
Molecular Regulation Of Endocytosis written by Brian Ceresa and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-06 with Science categories.
Molecular Regulation of Endocytosis is a compilation of scientific "short stories" about the entry of external substances into cells. As one can see from the chapters, endocytosis regulates diverse processes such as homeostasis of the cell, signal transduction, entry of pathogens and viruses. In addition to the experimental techniques embedded in each chapter, entire chapters are dedicated to experimental approaches that will be useful to all scientists and their model systems. For those more clinically oriented, the final chapters look to the future and ways of utilizing endocytic pathways for therapeutic purposes.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Coronaviruses And Arteriviruses
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Author : Luis Enjuanes
language : en
Publisher: Springer Science & Business Media
Release Date : 1998-08-31
Coronaviruses And Arteriviruses written by Luis Enjuanes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-31 with Science categories.
Proceedings of the VIIth International Symposium held in Segovia, Spain, May 10-15, 1997
Desk Encyclopedia Of Plant And Fungal Virology
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Author : Marc H.V. van Regenmortel
language : en
Publisher: Academic Press
Release Date : 2009-10-13
Desk Encyclopedia Of Plant And Fungal Virology written by Marc H.V. van Regenmortel and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-13 with Science categories.
This volume consists of 85 chapters that highlight recent advances in our knowledge of the viruses that infect plants and fungi. It begins with general topics in plant virology including movement of viruses in plants, the transmission of plant viruses by vectors, and the development of virus-resistant transgenic plants. The second section presents an overview of the properties of a selection of 20 well-studied plant viruses, 23 plant virus genera and a few larger groups of plant viruses. The third section, which is abundantly illustrated, highlights the most economically important virus diseases of cereals, legumes, vegetable crops, fruit trees and ornamentals. The last section describes the major groups of viruses that infect fungi. The most comprehensive single-volume source providing an overview of virology issues related to plant and fungi Bridges the gap between basic undergraduate texts and specialized reviews Concise and general overviews of important topics within the field will help in preparation of lectures, writing reports, or drafting grant applications