Metabolomics And Its Impact On Health And Diseases
DOWNLOAD
Download Metabolomics And Its Impact On Health And Diseases PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Metabolomics And Its Impact On Health And Diseases book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Metabolomics And Its Impact On Health And Diseases
DOWNLOAD
Author : Veronica Ghini
language : en
Publisher: Springer Nature
Release Date : 2023-03-03
Metabolomics And Its Impact On Health And Diseases written by Veronica Ghini and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-03 with Medical categories.
This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
Whole Grains And Health
DOWNLOAD
Author : Rikard Landberg
language : en
Publisher: John Wiley & Sons
Release Date : 2021-05-24
Whole Grains And Health written by Rikard Landberg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-24 with Technology & Engineering categories.
WHOLE GRAINS AND HEALTH The updated guide to whole grains and their integral role in nutritional health In an increasingly health-conscious society, the potential benefits of whole grain products are of paramount importance to manufacturers, dieticians, and consumers alike. Whole Grains and Health covers all aspects of this crucial topic, presenting a data-driven study of whole grains’ functional components, associated biomarkers and overall impact upon human health. Now in its second edition, the text has been revised and expanded to include six new chapters and groundbreaking new data. This essential guide features: Summaries of large research projects on the health effects of whole grain in Europe and the US New data on the associations between whole grain consumption and risk of developing chronic diseases Discussions of metabolomics and their use in addressing health effects and finding new biomarkers of both dietary exposure and health effects related to the diet Information on the use of genomics in studies of how gene-expression profiles change in response to whole grain intake Newly identified bioactive compounds in whole grains and whole grain fractions The new EU regulations on health claims that affect whole grain food products Providing information that will be of interest to food scientists, healthcare specialists and food industry professionals alike, the second edition of Whole Grains and Health is an essential resource for anyone concerned with the impact whole grains may have upon health.
Metabolomics In Health And Disease Biology
DOWNLOAD
Author :
language : en
Publisher: Elsevier
Release Date : 2024-02-26
Metabolomics In Health And Disease Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-26 with Science categories.
Metabolomics in Health and Disease Biology, Volume 104 covers this rapidly emerging field that aims for metabolic phenotyping and understanding the blueprint of metabolic pathways under various health and disease conditions by comprehensive analysis of metabolites. Chapters in this new release include Metabolomics approaches: Biomarkers to Disease mechanisms, Metabolomics in sleep disorders, Metabolomics in predicting the hallmark of Cancer Metabolism, Spectroscopic based rapid metabolic fingerprinting approaches for Cancer diagnosis, Lipidomics in assessing the health of osteoarthritis, Metabolomics Applications in Type 2 Diabetes mellitus, Metabolomics of Diabetic retinopathy, Metabolomics in Neurodegenerative disorders- Parkinson's disease, and Metabolomic of Neurodegenerative disorder: Alzheimer's Disease. - Presents crucial reviews from selected experts in the field of metabolomics, with cross-disciplinary contributions - Provides the latest insights into our understanding of diseases using metabolomics-based approaches - Includes graphical material for metabolomics application that provide useful information for ease of reading of audience
Gut Microbiome And Its Impact On Health And Diseases
DOWNLOAD
Author : Debabrata Biswas
language : en
Publisher: Springer Nature
Release Date : 2020-08-27
Gut Microbiome And Its Impact On Health And Diseases written by Debabrata Biswas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-27 with Technology & Engineering categories.
This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.
Integration Of Omics Approaches And Systems Biology For Clinical Applications
DOWNLOAD
Author : Antonia Vlahou
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-21
Integration Of Omics Approaches And Systems Biology For Clinical Applications written by Antonia Vlahou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-21 with Science categories.
Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.
A Practical Guide To Metabolomics Applications In Health And Disease
DOWNLOAD
Author : Julijana Ivanisevic
language : en
Publisher: Springer Nature
Release Date : 2024-02-26
A Practical Guide To Metabolomics Applications In Health And Disease written by Julijana Ivanisevic and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-26 with Medical categories.
This well-accessible textbook constitutes a practical guide to metabolomics approaches and applications in an integrative manner. Illustrated by numerous real-life examples and case studies the book teaches how to set up and carry out metabolomics experiments, from sample collection to storage techniques, and guides the reader through the potentials and challenges of metabolite analysis. In addition, this textbook shows how to obtain insights into molecular mechanisms deployed in different physiological contexts (e.g., exercise, healthy ageing) as well as in different (metabolic) diseases, be it Diabetes, Cancer, Alzheimer ́s Disease, Asthma or others. The book brings together knowledge from biochemical, biological, and medical aspects, and further equips the reader with know-how from sample collection and handling to data processing, analysis and interpretation. This textbook is a must-have for advanced undergraduates and graduate students interested in applied biochemistry and metabolomics, as well as for instructors who teach courses in biomedicine, physiology or biochemistry.
Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis
DOWNLOAD
Author : George G. Harrigan
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-01-31
Metabolic Profiling Its Role In Biomarker Discovery And Gene Function Analysis written by George G. Harrigan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-31 with Medical categories.
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.
Metabolomics In Neurodegenerative Disease
DOWNLOAD
Author : Brian Green
language : en
Publisher: MDPI
Release Date : 2020-04-21
Metabolomics In Neurodegenerative Disease written by Brian Green and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-21 with Science categories.
The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
Toxicological Risk Assessment And Multi System Health Impacts From Exposure
DOWNLOAD
Author : Aristidis M. Tsatsakis
language : en
Publisher: Elsevier
Release Date : 2021-08-01
Toxicological Risk Assessment And Multi System Health Impacts From Exposure written by Aristidis M. Tsatsakis and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-01 with Medical categories.
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Mass Spectrometry
DOWNLOAD
Author : Anshul Pandey
language : en
Publisher: Educohack Press
Release Date : 2025-02-20
Mass Spectrometry written by Anshul Pandey and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.
"Mass Spectrometry: Techniques and Applications" is a comprehensive guide to understanding and mastering the principles, techniques, and applications of this powerful analytical method. We cover a wide range of topics, delving into the intricacies of ionization methods, mass analyzers, ion detection, and data analysis strategies crucial for accurate and reliable mass spectrometry results. We explore the fundamentals of mass spectrometry, including ionization and fragmentation principles, isotopic patterns, and mass-to-charge ratio calculations. Various ionization techniques such as electrospray ionization (ESI), matrix-assisted laser desorption/ionization (MALDI), and electron ionization (EI) are elucidated, providing insights into their mechanisms and applications. Advanced topics like tandem mass spectrometry (MS/MS), high-resolution mass spectrometry (HRMS), and ion mobility spectrometry (IMS) are also covered, offering a comprehensive understanding of cutting-edge techniques and instrumentation. Practical aspects of mass spectrometry, including method development, calibration strategies, data interpretation, and troubleshooting, are detailed to help researchers, students, and professionals navigate experiments effectively. Additionally, we showcase the diverse applications of mass spectrometry across fields such as pharmaceuticals, environmental analysis, metabolomics, proteomics, forensics, and materials science. Case studies, real-world examples, and emerging trends provide valuable insights into the role of mass spectrometry in advancing scientific discovery and addressing societal challenges. With clear explanations, illustrative diagrams, and practical tips, "Mass Spectrometry: Techniques and Applications" serves as an indispensable resource for anyone seeking a comprehensive and up-to-date reference on this essential analytical technique.