Modeling Sensorineural Hearing Loss
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Modeling Sensorineural Hearing Loss
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Author : Walt Jesteadt
language : en
Publisher: Routledge
Release Date : 2019-01-04
Modeling Sensorineural Hearing Loss written by Walt Jesteadt and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-04 with Education categories.
A recent study indicates that 20 million people in the United States have significant sensorineural hearing loss. Approximately 95% of those people have partial losses, with varying degrees of residual hearing. These percentages are similar in other developed countries. What changes in the function of the cochlea or inner ear cause such losses? What does the world sound like to the 19 million people with residual hearing? How should we transform sounds to correct for the hearing loss and maximize restoration of normal hearing? Answers to such questions require detailed models of the way that sounds are processed by the nervous system, both for listeners with normal hearing and for those with sensorineural hearing loss. This book contains chapters describing the work of 25 different research groups. A great deal of research in recent years has been aimed at obtaining a better physiological description of the altered processes that cause sensorineural hearing loss and a better understanding of transformations that occur in the perception of those sounds that are sufficiently intense that they can still be heard. Efforts to understand these changes in function have lead to a better understanding of normal function as well. This research has been based on rigorous mathematical models, computer simulations of mechanical and physiological processes, and signal processing simulations of the altered perceptual experience of listeners with sensorineural hearing loss. This book provides examples of all these approaches to modeling sensorineural hearing loss and a summary of the latest research in the field.
Psychoacoustics
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Author : Jennifer J. Lentz
language : en
Publisher: Plural Publishing
Release Date : 2023-11-27
Psychoacoustics written by Jennifer J. Lentz and has been published by Plural Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-27 with Medical categories.
Psychoacoustics: Auditory Perception of Listeners with Normal Hearing and Hearing Loss, Second Edition provides an overview of the field of psychoacoustics, with a primary focus on auditory perception. The book retains its focus on applications of psychoacoustics to clinical audiology, and its modular organization, with each chapter including relevant information around a specific topic. Within each chapter, acoustics, physiology, and perception by adult listeners with normal hearing and those with hearing loss, as they relate to that topic, are presented. The influence of hearing loss on these general auditory abilities is discussed in every chapter. Components of the book also include the role of psychoacoustics in audiological assessment and treatment. The text is ideal for audiology students who intend on having a clinical career and need an understanding of both normal and impaired auditory perception. It is intended to give students sufficient information to understand how the ear achieves auditory perception, what the capabilities of the ear are, and how hearing loss influences that perception. It also provides students with a foundation for further study in the area and to apply psychoacoustic principles to diagnostic audiology and audiological rehabilitation. New to the Second Edition: * 70 new figures to clarify some points and facilitate students’ understanding of the material * New chapter that focuses exclusively on the perception by individuals wearing hearing aids and cochlear implants * New section on the perceptual consequences of sensorineural hearing loss on everyday listening added to each chapter * Revamped chapter on Psychoacoustics and Advanced Clinical Auditory Assessment now solely addresses elements within diagnostic audiology that are based on psychoacoustics, with added content on tinnitus assessment, automated (Békésy) audiometry, retrocochlear and pseudohypacusis evaluation, and the identification of dead regions * Enhanced focus on inclusivity, such as alternative versions of some demonstrations designed to be more accessible to individuals with hearing loss, and a new section on the contributions of women and BIPOC scientists to the field of psychoacoustics Key Features: * Learning objectives and summaries begin and end each chapter to convey the goals of the text and review student comprehension * Each chapter contains exercises designed to develop critical thinking about psychoacoustics * Chapters include the following: introduction, relevant acoustics, important physiological studies, perception by normal-hearing listeners, and perception by listeners who have sensorineural hearing loss * Emphasis on applied learning for more effective and efficient learning of the material Disclaimer: Please note that ancillary content such as lab exercises are not included as published in the original print version of this book.
The Micro Vasculature Of The Cochlea
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Author : Mattia Carraro
language : en
Publisher:
Release Date : 2016
The Micro Vasculature Of The Cochlea written by Mattia Carraro and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
This thesis concerns the role of cochlear microvasculature in normal hearing function and in pathological conditions that result in hearing loss. In animal models we have investigated two major types of sensorineural hearing loss where degeneration of the stria vascularis has been implicated, namely presbyacusis and hearing loss associated with cytomegalovirus (CMV) infection. The former eventual affects all aging humans; the latter is a common etiology for congenital hearing loss in infants. The focus of experimental work is on the capillary networks of the cochlea. We chose to use corrosion cast techniques to visualize and quantify capillary vessel parameters. For the small and delicate cochleas of our mouse models, this required extensive technical improvements to corrosion casting methodology. These innovations proved successful. Three experimental animal model studies were made. The first involved analysis, and modeling of strial feeding arterioles in normal subject. The hypothesis posed was that the highly convoluted structure of these vessels acts to dampen cardiovascular pulsations within the cochlea and thereby prevent self-stimulation by such biological noise. The results from this study support the hypothesis. In our murine models of presbyacusis and of CMV infection we correlated loss of auditory thresholds measured with ABR methods, with degenerative changes to cochlear microvasculature. In mice with age-related, high frequency hearing loss, we report significant vascular degeneration of stria vascularis in basal (high frequency) cochlear areas compared to more apical regions. After CMV infection in newborn mice, we observed at 6 weeks a wide range of auditory threshold changes. At 8 weeks post-infection, the cochleas had suffered a wide range of vascular damage. The most vulnerable structure was stria vascularis in the mid-apical cochlear turn. Our novel finding that vascular damage is the primary lesion after CMV infection is consistent with some clinical characteristics of this hearing loss type in infants.
Computational Models Of The Auditory System
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Author : Ray Meddis
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-16
Computational Models Of The Auditory System written by Ray Meddis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-16 with Medical categories.
The Springer Handbook of Auditory Research presents a series of comprehensive and synthetic reviews of the fundamental topics in modern auditory research. The v- umes are aimed at all individuals with interests in hearing research including advanced graduate students, post-doctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in fields of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in pe- reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beg- ning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Molecular Mechanisms Of Sensorineural Hearing Loss And Development Of Inner Ear Therapeutics
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Author : Srdjan M Vlajkovic
language : en
Publisher:
Release Date : 2021-10-25
Molecular Mechanisms Of Sensorineural Hearing Loss And Development Of Inner Ear Therapeutics written by Srdjan M Vlajkovic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with categories.
The sense of hearing is vulnerable to environmental challenges, such as exposure to noise. More than 1.5 billion people experience some decline in hearing ability during their lifetime, of whom at least 430 million will be affected by disabling hearing loss. If not identified and addressed in a timely way, hearing loss can severely reduce the quality of life at various stages. Some causes of hearing loss can be prevented, for example from occupational or leisure noise. The World Health Organization estimates that more than 1 billion young people put themselves at risk of permanent hearing loss by listening to loud music over long periods of time. Mitigating such risks through public health action is essential to reduce the impact of hearing loss in the community. The etiology of sensorineural hearing loss is complex and multifactorial, arising from congenital and acquired causes. This book highlights the diverse range of approaches to sensorineural hearing loss, from designing new animal models of age-related hearing loss, to the use of microRNAs as biomarkers of cochlear injury and drug repurposing for the therapy of agerelated and noise-induced hearing loss. Further investigation into the underlying molecular mechanisms of sensorineural hearing loss and the integration of the novel drug, cell, and gene therapy strategies into controlled clinical studies will permit significant advances in a field where there are currently many unmet needs.
Scientific Foundations Of Audiology
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Author : Anthony T. Cacace
language : en
Publisher: Plural Publishing
Release Date : 2016-04-15
Scientific Foundations Of Audiology written by Anthony T. Cacace and has been published by Plural Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-15 with Medical categories.
With advancements across various scientific and medical fields, professionals in audiology are in a unique position to integrate cutting-edge technology with real-world situations. Scientific Foundations of Audiology provides a strong basis and philosophical framework for understanding various domains of hearing science in the context of contemporary developments in genetics, gene expression, bioengineering, neuroimaging, neurochemistry, cochlear and mid-brain implants, associated speech processing and understanding, molecular biology, physics, modeling, medicine, and clinical practice. Key features of this text include: Highly technical information presented in a cohesive and understandable manner (i.e., concepts without complex equations)Discussion of integrating newly developed technology within the clinical practice of audiologyState-of-the-art contributions from a stellar array of international, world-class experts Scientific Foundations of Audiology is geared toward doctoral students in audiology, physics, and engineering; residents in otolaryngology, neurology, neurosurgery, and pediatrics; and those intermediaries between innovation and clinical reality.
National Strategic Research Plan For Hearing And Hearing Impairment And Voice And Voice Disorders
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Author :
language : en
Publisher:
Release Date : 1992
National Strategic Research Plan For Hearing And Hearing Impairment And Voice And Voice Disorders written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Communicative disorders categories.
Loudness
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Author : Mary Florentine
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-04
Loudness written by Mary Florentine and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-04 with Science categories.
Loudness is the primary psychological correlate of intensity. When the intensity of a sound increases, loudness increases. However, there exists no simple one-to-one correspondence between loudness and intensity; loudness can be changed by modifying the frequency or the duration of the sound, or by adding background sounds. Loudness also changes with the listener’s cognitive state. Loudness provides a basic reference for graduate students, consultants, clinicians, and researchers with a focus on recent discoveries. The book begins with an overview of the conceptual thinking related to the study of loudness, addresses issues related to its measurement, and later discusses the physiological effects of loud sounds, reaction times and electrophysiological measures that correlate with loudness. Loudness in the laboratory, loudness of steady-state sounds and the loudness of time-varying sounds are also covered, as are hearing loss and models.
Auditory Trauma Protection And Repair
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Author : Jochen Schacht
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-10
Auditory Trauma Protection And Repair written by Jochen Schacht and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-10 with Medical categories.
The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. This volume presents recent developments in research and their potential translation to the clinical setting. It brings together the basic and clinical sciences very nicely in that while most chapters are written by basic scientists, each topic has a pretty direct clinical application or implication.
Investigation Of Sensorineural Hearing Impairment Using A Center Clipping Model
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Author : Erik Ian Gilbert
language : en
Publisher:
Release Date : 1984
Investigation Of Sensorineural Hearing Impairment Using A Center Clipping Model written by Erik Ian Gilbert and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.