Molecular And Cellular Gerontology
DOWNLOAD
Download Molecular And Cellular Gerontology PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Molecular And Cellular Gerontology book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Molecular And Cellular Gerontology
DOWNLOAD
Author : Olivier Toussaint
language : en
Publisher:
Release Date : 2000
Molecular And Cellular Gerontology written by Olivier Toussaint and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Aging categories.
This work covers a number of relevant aspects of the molecular and cellular biology of ageing, a timely general topic highlighted by the United Nations' having declared 1999 the Year of the Elderly. The papers published here represent a wide range of complementary research areas: molecular and cellular aspects; theories of ageing; molecular basis of the loss of homeostatic maintenance mechanisms; lower and higher model organisms including transgenic animal models; the genetics of human longevity; clinical and molecular aspects of age-related diseases; and integrated systems like brain and immune system aging. It is hoped that the additions to knowledge of the molecular mechanisms of ageing provided by this volume may ultimately lead to the prevention of age-related diseases.
Aging At The Molecular Level
DOWNLOAD
Author : Thomas von Zglinicki
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Aging At The Molecular Level written by Thomas von Zglinicki and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major theory, but essentially to accepted knowledge. Aging at the Molecular Level examines the key elements in this transformation. Bringing together contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.
Molecular Basis Of Aging
DOWNLOAD
Author : A Roy
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Molecular Basis Of Aging written by A Roy and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Molecular Basis of Aging is a collection of papers that discuss the molecular aspects of aging in the light of molecular biology, biochemical gerontology, and genetics. Each chapter of the book contains a different study about the topic, which includes the effects of aging on DNA synthesis; the amplification of extrachromosomal circular copies and mitochondrial DNA during aging; and the altered actions of hormones and neurotransmitters during aging. The book also encompasses the loss of responsiveness to growth factors in cell senescence; the integration of cellular-molecular and neuroendocrine concepts of aging; changes and inactivation of enzymes during aging; and the relationship of aging with free radicals. The text is recommended for molecular biologists, biochemists, and gerontologists who wish to study further the effects of aging on the body on a molecular level.
Molecular Biology Of Aging
DOWNLOAD
Author : Leonard Guarente
language : en
Publisher: CSHL Press
Release Date : 2008
Molecular Biology Of Aging written by Leonard Guarente and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Aging categories.
This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer.
Molecular Cellular And Metabolic Fundamentals Of Human Aging
DOWNLOAD
Author : Evandro Fei Fang
language : en
Publisher: Academic Press
Release Date : 2022-10-23
Molecular Cellular And Metabolic Fundamentals Of Human Aging written by Evandro Fei Fang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-23 with Science categories.
Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion. The book also considers the impact of aging within the immune system, the relationship between aging and diseases such as cancers and neurodegenerative conditions, and provides an overview on the dialogue surrounding the topic of aging beyond basic biology. Covers the basic hallmarks of aging and their relevance in various diseases, such as cancer and Alzheimer’s disease Discusses the impact of genetic damage and how changes in genetic expression patterns affect the process of aging Highlights recurring themes and key principles shared across the hallmarks of aging Considers NAD+ depletion and defective autophagy as emerging aspects that impact human aging
Cell Aging Molecular Mechanisms And Implications For Disease
DOWNLOAD
Author : Christian Behl
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-18
Cell Aging Molecular Mechanisms And Implications For Disease written by Christian Behl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-18 with Science categories.
Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical and medical research. The plethora of theories on aging – some of which have been discussed for decades – are neither isolated nor contradictory but instead can be connected in a network of pathways and processes at the cellular and molecular levels. This book summarizes the most prominent and important approaches, focusing on telomeres, DNA damage and oxidative stress as well as on the possible role of nutrition, the interplay between genes and environment (epigenetics) and intracellular protein homeostasis and introduces some genes that have actually extended life spans in animal models. Linking these different determinants of aging with disease, this volume aims to reveal their multiple interdependencies. We see that there is no single “perfect” theory of aging and that instead it is possible to define what the authors call the molecular aging matrix of the cell. A better knowledge of its key mechanisms and the mutual connections between its components will lead to a better understanding of age-associated disorders such as Alzheimer’s disease.
Molecular Gerontology
DOWNLOAD
Author : S.I. Rattan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Gerontology written by S.I. Rattan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Esteemed researchers from different European laboratories provide state-of-the-art studies on biology and ageing, along with guidelines for future investigations. They cover such issues in molecular gerontological research as regulation of gene expression from DNA to RNA to functional proteins, origin of various age-associated diseases, genetic regulation of ageing and longevity, and different mechanisms of defense and repair. Other contributions evaluate new technologies, including transgenic organisms, and the use of nutritional and chemical modulators of ageing and lifespan.
Cellular And Molecular Aspects Of Aging
DOWNLOAD
Author : John W. Eaton
language : en
Publisher:
Release Date : 1985-09
Cellular And Molecular Aspects Of Aging written by John W. Eaton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-09 with categories.
Times Cells And Aging
DOWNLOAD
Author : Bernard Strihler
language : en
Publisher: Academic Press
Release Date : 1977-01-28
Times Cells And Aging written by Bernard Strihler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-01-28 with Science categories.
Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism's deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
The Underlying Molecular Cellular And Immunological Factors In Cancer And Aging
DOWNLOAD
Author : Stringer Sue Yang
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Underlying Molecular Cellular And Immunological Factors In Cancer And Aging written by Stringer Sue Yang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Background Cancer is a variety of malignancies generally associated with aging. As the overall health technology and health care delivery improved with the advances made in medicine and science in the United States, the life expectancy of the population also increased. The average life expectancy in the U. S. A. has increased from 49 years at the end of 1900 to 75 years today in 1990 (1-3). The population of 65 years and older that constituted 25. 5 million or 11. 3% of the total U. S. population in 1980(4) has now increased to 31. 1 million or 12. 5% of the population according to the 1990(5) census. As cancer diagnosis and treatment have improved, cancer mortality among patients under 55 has been significantly reduced within recent years *1; however, cancer incidence under 55 is still increasing at about 0. 4% per year (as compared to 1. 0% for all ages or 0. 6% for