Molecular Mechanisms For Reprogramming Hippocampal Development And Function By Early Life Stress
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Molecular Mechanisms For Reprogramming Hippocampal Development And Function By Early Life Stress
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Author : Xiao-Dong Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2016-04-06
Molecular Mechanisms For Reprogramming Hippocampal Development And Function By Early Life Stress written by Xiao-Dong Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-06 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.
Molecular Mechanisms For Reprogramming Hippocampal Development And Function By Early Life Stress
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Author :
language : en
Publisher:
Release Date : 2016
Molecular Mechanisms For Reprogramming Hippocampal Development And Function By Early Life Stress written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.
Programming Hpa Axis By Early Life Experience Mechanisms Of Stress Susceptibility And Adaptation
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Author : Rachel Yehuda
language : en
Publisher: Frontiers Media SA
Release Date : 2015-03-16
Programming Hpa Axis By Early Life Experience Mechanisms Of Stress Susceptibility And Adaptation written by Rachel Yehuda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-16 with Diseases of the endocrine glands. Clinical endocrinology categories.
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
The Neurobiological Basis Of Suicide
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Author : Yogesh Dwivedi
language : en
Publisher: CRC Press
Release Date : 2012-06-25
The Neurobiological Basis Of Suicide written by Yogesh Dwivedi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-25 with Medical categories.
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
The Oxford Handbook Of Molecular Psychology
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Author : Turhan Canli
language : en
Publisher:
Release Date : 2015
The Oxford Handbook Of Molecular Psychology written by Turhan Canli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.
This entry in the Oxford Library of Psychology compiles cutting-edge research organized around the concept "molecular psychology," which applies principles of molecular biology to the study of behavior and its neural underpinnings. Chapters draw on molecular methods covering candidate genes, genome-wide association studies, copy number variations, gene expression studies, and epigenetics while addressing the ethical, legal, and social issues to emerge from this new and exciting research approach.
Frontiers In Synaptic Plasticity Dendritic Spines Circuitries And Behavior
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Author : Alberto A. Rasia-Filho
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-22
Frontiers In Synaptic Plasticity Dendritic Spines Circuitries And Behavior written by Alberto A. Rasia-Filho and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-22 with Medicine (General) categories.
The term “synaptic plasticity” is a broad concept, which is studied with a variety of experimental approaches. One focus is the impact of changes in synaptic, neuronal and glial morphology on brain circuitry and behavior. In this regard, unique animal models have been key to the study of affective and social behaviors and neurological and psychiatric diseases. However, there is a paucity of compilations directed toward the correlation of alterations in synaptic structure with various physiological and behavioral paradigms. This Frontiers Research Topic will, therefore, serve as an exciting forum for the exchange of novel hypotheses and data and an important resource and reference for investigators studying synaptic and brain plasticity, as well as those in related fields.
Social And Non Social Reward Neural Mechanisms Implicated In Reward Processing Across Domains And Contexts
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Author : Johanna M. Jarcho
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-21
Social And Non Social Reward Neural Mechanisms Implicated In Reward Processing Across Domains And Contexts written by Johanna M. Jarcho and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-21 with categories.
Translational Research Models And Methods For Mother Infant Interactions And Developmental Studies
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Author : Josephine Johns
language : en
Publisher: Frontiers Media SA
Release Date : 2012-10-01
Translational Research Models And Methods For Mother Infant Interactions And Developmental Studies written by Josephine Johns and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-01 with categories.
The disruption of mother-infant interactions can have life-long detrimental consequences for offspring and mothers. This topic of Frontiers will focus on maternal-infant interactions including factors that may affect or alter infant or child development and maternal response capability in clinical and preclinical (animal) populations. Articles may highlight topics such as drug abuse, maternal neglect, altered reward systems, stress, biological and neural system development, child and infant behavioral development, genetics/epigenetics and intergenerational studies. Submissions can include research methods papers, reviews, original research articles, techniques and opinion articles that address the topics of interest. This Research Topic will highlight translational research including common measures and results found in both animal and human studies. Please contact one of the Editors for submission proposals or for additional information.
Perinatal Inflammation And Adult Psychopathology
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Author : Antonio L. Teixeira
language : en
Publisher: Springer Nature
Release Date : 2020-04-07
Perinatal Inflammation And Adult Psychopathology written by Antonio L. Teixeira and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-07 with Medical categories.
Perinatal psychiatry is an emerging field that investigates the role of perinatal events – for example pregnancy complications and infections – in the development of neuropsychiatric conditions, such as schizophrenia and mood disorders. Among the implicated pathological mechanisms, perinatal-induced inflammation seems to play a major role and is being considered as a potential target for therapeutic intervention. Bringing together various approaches in the field (preclinical and clinical, epidemiological, immunological and genetic methods), the book discusses the available evidence, the putative mechanisms and the challenges ahead.
Adaptive And Maladaptive Aspects Of Developmental Stress
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Author : Giovanni Laviola
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-31
Adaptive And Maladaptive Aspects Of Developmental Stress written by Giovanni Laviola and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Medical categories.
Since the very early stages of life, we all experience some form of stress. Stressors can be mild to severe and can range from unsuccessfully longing for maternal milk in infancy, to recklessly wiggling on a motorbike to be on time to watch the NBA finals on TV, to breaking up a relationship. All those events that we call “stress” have the capability of perturbing a given state of psychological and physiological equilibrium and moving it to a different level. The transition from crawling to walking has to be considered a form of stress as much as losing a job. It is through a continuous cross-talk between environmental stressors and individual adaptations that we build our personalities and our ways to cope with daily hassles. External challenges should not necessarily be regarded as “bad”, but instead seen as constructive forces forming our ability to navigate a changing world. What is stress good for? What is stress bad for? When and why do we need to be “stressed”? Should we worry about stress? When does stress equate to “normality”? When does it turn into pathology? We hope with this book to provide some answers to these fundamental questions.