Molecular Mechanisms Of Biological Recognition
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Molecular Mechanisms Of Biological Recognition
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Author : Manfred Eigen
language : en
Publisher: Elsevier Science & Technology
Release Date : 1979
Molecular Mechanisms Of Biological Recognition written by Manfred Eigen and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Science categories.
Specific Interaction And Biological Recognition Processes
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Author : Zeno Simon
language : en
Publisher: CRC Press
Release Date : 1993-06-16
Specific Interaction And Biological Recognition Processes written by Zeno Simon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-06-16 with Science categories.
Specific Interaction and Biological Recognition Processes is devoted to two major aspects of biological processes: specificity in biological recognition and the recognition processes themselves. Topics covered in specificity include the theoretical basis for specificity in biological recognition; the thermodynamic and chemical equilibrium background; and consideration of the relationship between size of combining sites and specificity. The use of semi-emperical potentials for calculating interaction energies and the potential of quantum chemistry methods for calculating receptor-effector affinities are also discussed. The various recognition processes described include DNA replication, transcription, translation, enzymatic reactions, transmembrane transport processes, mechanisms of action of hormones and other chemical messengers, and self-nonself recognition in immunology. Specific Interaction and Biological Recognition Processes will be a useful reference for molecular biologists, biochemists, enzymologists, immunologists oncologists, pharmaceutical researchers, and others interested in the topic.
Molecular Mechanisms For Sensory Signals
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Author : Edward M. Kosower
language : en
Publisher: Princeton University Press
Release Date : 2017-03-14
Molecular Mechanisms For Sensory Signals written by Edward M. Kosower and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-14 with Science categories.
Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Chemical Recognition In Biology
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Author : F. Chapeville
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemical Recognition In Biology written by F. Chapeville and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Studies of chemical recognition in biology were initiated about half a century ago with the flrst kinetic data obtained on enzyme catalysis and inhibition. They led to a rather static representation of the recognition process illustrated by the lock and key model that still continues to influence our overall image of recognition and its specificity. In several cases, crystallographic studies of enzyme-substrate complexes have supported this model. Indeed, in a crystallized ligand-enzyme complex, a close fltting is observed between the active center of the enzyme and the functional groups of the ligand. How ever, this does not necessarily result from a direct recognition process between rigid structures, but may result from a progressive adaptation during which the initial struc tures of the enzyme and the ligand are modified (induced-flt mechanism). Recently, a great deal of work has been devoted to the study of recognition in more complex systems such as the replication or the translation machin~ries; clearly, the extraordinary precision of such systems cannot be explained solely in terms of physical matching between enzymes and their substrates. This has led to a noticeable change of perspective in these areas. As a result of the new kinetic viewpoint, one rather focuses on the time-course of the processes, on the kinetic balance between steps of the reaction, on the energy-accuracy relationships and on the strategies which permit the achievement of high precision using relatively error-prone components in an appropriate dynamic interplay.
Molecular Recognition Mechanisms
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Author : Michel Delaage
language : en
Publisher: Wiley-VCH
Release Date : 1991
Molecular Recognition Mechanisms written by Michel Delaage and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Essentials Of Chemical Biology
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Author : Andrew D. Miller
language : en
Publisher: John Wiley & Sons
Release Date : 2023-12-27
Essentials Of Chemical Biology written by Andrew D. Miller and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-27 with Science categories.
Essentials of Chemical Biology Discover a detailed knowledge of concepts and techniques that shape this unique multi-discipline Chemical Biology is devoted to understanding the way that Biology works at the molecular level. This is a problem-driven multi-discipline, incorporating as it does Organic, Physical, Inorganic, and Analytical Chemistry alongside newer emerging molecular disciplines. In recent years, Chemical Biology has emerged as a vibrant and growing multi-discipline distinct from Biochemistry that is focused on the quantitative analyses of the structures and functions of biological macromolecules and macromolecular lipid assemblies, at first in isolation, then in vitro and in vivo. The second edition of the Essentials of Chemical Biology begins with a thorough introduction to the structure of biological macromolecules and macromolecular lipid assemblies, before moving on to the principles of chemical and biological synthesis, followed by descriptions of a comprehensive variety of research techniques and experimental methods. In addition, the second edition now includes new sections on the behaviour of biological macromolecules and macromolecular lipid assemblies in cells in vitro and in organisms in vivo. Given this, the second edition of the Essentials of Chemical Biology promises to cement itself as the leading introduction to Chemical Biology, incorporating descriptions of cutting-edge research wherever appropriate. Hence, readers of the second edition of the Essentials of Chemical Biology will find: a general expansion in understanding of basic molecular mechanisms in Biology moving towards cellular and organismal mechanisms entirely new chapters covering miniaturization and array technologies, Chemical Cell Biology, and the interface between Chemical Biology and Nanotechnology updates to chapters reflecting recent research developments an increased engagement with medical applications Essentials of Chemical Biology is ideal for advanced undergraduates or (post) graduate students in Chemical Biology and adjacent fields.
Molecular Recognition Of Dna Double Helix
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Author : Abhijit Saha
language : en
Publisher: Springer
Release Date : 2018-03-22
Molecular Recognition Of Dna Double Helix written by Abhijit Saha and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-22 with Science categories.
In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.
Molecular Mechanisms Of Phagocytosis
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Author : Carlos Rosales
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-07
Molecular Mechanisms Of Phagocytosis written by Carlos Rosales and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-07 with Science categories.
Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function. Molecular Mechanisms of Phagocytosis was prepared as a series of up-to-date essays (chapters) that describe the present knowledge on the various steps of the phagocytic process from initial cell contact, through internalization of the foreign particle, to the final phagosome formation where the phagocytosed particle is destroyed.
Molecular Mechanisms Of Neural Development And Insights Into Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-03-09
Molecular Mechanisms Of Neural Development And Insights Into Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-09 with Science categories.
Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series
The Molecular Basis Of Sex And Differentiation
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Author : Milton H. Saier
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Molecular Basis Of Sex And Differentiation written by Milton H. Saier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Man's mind stretched to a new idea never goes back to its original dimensions Oliver Wendell Holmes Our current understanding of sex and biological differentiation results from the application of three principal experimental approaches to these subjects: those of the physiologist, the biochemist, and the geneticist. These three approaches are illustrated by the materials presented in the chapters of this volume. Chapters 1-5 emphasize conceptualization of developmental processes, describing systems principally from the standpoint of the physiologist. Structures and functions are defined with only occasional reference to specific molecular details. Chapters 6- 10 present the views of the biochemist, attempting to describe functions influ encing or regulating cellular behavior at the molecular level. And Chapters 11- 14 illustrate the approaches of the modem-day geneticist in his attempts to gain a detailed understanding of processes controlling gene expression. While it is possible to delineate these three major sections, each emphasizing a distinct experimental approach, it must be realized that the yield of knowledge increases exponentially with the number of experimental approaches available to the investigator. Information resulting from the application of each of these approaches must converge to give the same answers for anyone biological phenomenon in anyone experimental system. Further, if we can learn of details regarding a particular process by applying different experimental approaches, our postulates concerning the underlying molecular mechanisms are likely to be more accurate. But biological systems are not unrelated.