Multi Component Reactions In Molecular Diversity
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Multi Component Reactions In Molecular Diversity
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Author : Jean-Philippe Goddard
language : en
Publisher: John Wiley & Sons
Release Date : 2020-04-28
Multi Component Reactions In Molecular Diversity written by Jean-Philippe Goddard and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-28 with Science categories.
While very useful for studying syntheses of molecular diversity, multi-component reactions also offer rapid access to a variety of complex molecules that are relevant for biological applications. Multi-component Reactions in Molecular Diversity analyzes these reactions, whether they are realized by organometallic, ionic or even radical processes. It highlights popular methods based on monotype reactions (cascade, tandem, domino) and their efficiency and academic industrial domain are illustrated. This book also investigates the most efficient ways to prepare complex molecules. Multi-component reactions are in tune with the concepts of atom and steps economy, which are of prior importance in all the reported processes ? from the laboratory to the pilot scale. The essential criteria for green chemistry are also examined in the book in detail.
Diversity Oriented Synthesis
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Author : Andrea Basso
language : en
Publisher: Frontiers Media SA
Release Date : 2019-03-22
Diversity Oriented Synthesis written by Andrea Basso and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with categories.
Has the concept of Diversity Oriented Synthesis remained unchanged over these two decades, or do we observe improvements or deviations from the original guidelines drawn by the pioneers? The aim of this Research Topic is to collect contributions on the state-of-the-art and progress of Diversity Oriented Synthesis, and to foresee its shape in the next decade.
Multicomponent Reactions Towards Heterocycles
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Author : Erik Van der Eycken
language : en
Publisher: John Wiley & Sons
Release Date : 2022-03-21
Multicomponent Reactions Towards Heterocycles written by Erik Van der Eycken and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-21 with Science categories.
Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.
Synthesis Of Heterocycles Via Multicomponent Reactions Ii
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Author : Romano V. A. Orru
language : en
Publisher: Springer
Release Date : 2010-07-26
Synthesis Of Heterocycles Via Multicomponent Reactions Ii written by Romano V. A. Orru and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-26 with Science categories.
Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery
Molecular Diversity And Combinatorial Chemistry
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Author : Michael C. Pirrung
language : en
Publisher: Elsevier
Release Date : 2004-10-17
Molecular Diversity And Combinatorial Chemistry written by Michael C. Pirrung and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-17 with Language Arts & Disciplines categories.
Written for advanced undergraduate and graduate students, this textbook makes the main concepts of combinatorial chemistry accessible to the non-specialist.
Multicomponent Reactions
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Author : Raquel P. Herrera
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-01
Multicomponent Reactions written by Raquel P. Herrera and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-01 with Science categories.
Addressing a dynamic aspect of organic chemistry, this bookdescribes synthetic strategies and applications for multicomponentreactions – including key routes for synthesizing complexmolecules. • Illustrates the crucial role and theimportant utility of multicomponent reactions (MCRs) to organicsyntheses • Compiles novel and efficient syntheticmulticomponent procedures to give readers a complete picture ofthis class of organic reactions • Helps readers to design efficient andpractical transformations using multicomponent reactionstrategies • Describes reaction background,applications to synthesize complex molecules and drugs, andreaction mechanisms
Mcr 2009
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Author : Maxim A. Mironov
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-26
Mcr 2009 written by Maxim A. Mironov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-26 with Science categories.
Multi-component reactions warrant ever-increasing attention, as they are ideally suited for combinatorial synthesis (either on solid support or in solution) of libraries of products relevant to catalysis, such as agrochemicals or pharmaceuticals. Therefore, the study and implementation of MCRs possesses a wide range of appeal and applicability. A broad and expanding audience of scientists and students continues to apply the concepts of multi-component chemistry to an array of disciplines—this collection of research offers an angle for each and brings together the vast scope of possibilities within the greater community.
Multicomponent Reactions
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Author : K.L. Ameta, Ph.D.
language : en
Publisher: CRC Press
Release Date : 2017-09-20
Multicomponent Reactions written by K.L. Ameta, Ph.D. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-20 with Medical categories.
This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Synthesis Of Heterocycles Via Multicomponent Reactions Ii
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Author : Romano V. A. Orru
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-05
Synthesis Of Heterocycles Via Multicomponent Reactions Ii written by Romano V. A. Orru and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-05 with Science categories.
Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery
Isocyanide Based Multicomponent Reactions
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Author : Jonathan G. Rudick
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-20
Isocyanide Based Multicomponent Reactions written by Jonathan G. Rudick and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-20 with categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.