Multi Omics In Studying The Mechanisms Of Anti Cancer Drugs Resistance And Toxicity
DOWNLOAD
Download Multi Omics In Studying The Mechanisms Of Anti Cancer Drugs Resistance And Toxicity PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Multi Omics In Studying The Mechanisms Of Anti Cancer Drugs Resistance And Toxicity book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Multi Omics In Studying The Mechanisms Of Anti Cancer Drugs Resistance And Toxicity
DOWNLOAD
Author : Jian Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-18
Multi Omics In Studying The Mechanisms Of Anti Cancer Drugs Resistance And Toxicity written by Jian Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-18 with Science categories.
Multi Omics Application In Exploring Potential Biomarkers Targeting Resistance Of Anti Cancer Drugs
DOWNLOAD
Author : Hailin Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-30
Multi Omics Application In Exploring Potential Biomarkers Targeting Resistance Of Anti Cancer Drugs written by Hailin Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-30 with Science categories.
Cancer remains a critical concern in global health due to its high prevalence and mortality rates. Despite significant advancements in the development of anti-cancer drugs, drug resistance continues to pose a major challenge in clinical treatments. Drug resistance may be either intrinsic i.e., pre-existent resistance present in the tumor cells even before exposure to chemotherapy, or acquired resistance i.e., induced by drugs during or after treatment of tumors with anticancer compounds. Anti-cancer treatments such as chemotherapy, targeted therapy, and immunotherapy are highly genotype-related interventions. Coding and Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), lncRNAs, circular RNAs (circRNAs), and PIWI-RNA (piRNA) have been shown to play important roles in tumor formation and therapeutic resistance. lncRNAs can activate DNA damage repair, silence tumor suppressor genes, and modulate cancer-related epigenetic changes at the chromatin level in terms of histone modifications, DNA methylation, and altering chromatin architecture.
Systems Biology And In Depth Applications For Unlocking Diseases
DOWNLOAD
Author : Babak Sokouti
language : en
Publisher: Elsevier
Release Date : 2024-11-05
Systems Biology And In Depth Applications For Unlocking Diseases written by Babak Sokouti and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-05 with Science categories.
Systems Biology and In-Depth Applications for Unlocking Diseases provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment.Systematically written in 4 parts, this book first provides an introduction and history of systems biology; second, it provides the tools and resources needed for the structure and function of biological systems; next, it provides the evidence of systems biology in action to better understand disease connections; and finally, it provides the extensions of systems biology in various scientific fields including pharmacology, immunology, vaccinology, neuroscience, virology, and medicine. Examples include big data techniques, scale networks, mathematical model development, and much more.This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, whether needed for immediate application or for building a comprehensive understanding of the field. - Provides detailed and comprehensive coverage of the field of systems biology - Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment - Makes effective steps towards personalized medicine in the treatment of disease - Explains effective disease treatment strategies at early diagnosis stages
Biotechnology Multiple Omics And Precision Breeding In Medicinal Plants
DOWNLOAD
Author : Jen-Tsung Chen
language : en
Publisher: CRC Press
Release Date : 2025-03-27
Biotechnology Multiple Omics And Precision Breeding In Medicinal Plants written by Jen-Tsung Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-27 with Science categories.
Biotechnology, Multiple Omics, and Precision Breeding in Medicinal Plants explores the various methods for advancing medicinal plant research. It covers a wide range of approaches, including integrated and advanced plant biotechnology, mutagenesis, nanotechnology, genome-wide association studies, multiple omics tools, and high-throughput technologies. The book highlights the significant impact of combining pan-genomics with metabolomics in medicinal plant research, particularly in understanding how genetic diversity influences the profiles of secondary metabolites and the therapeutic potential of these plants. FEATURES: Explores ways to improve the production of secondary metabolites and bioactive compounds in key medicinal plants Features information on bioinformatics, artificial intelligence models, molecular markers, and genome editing techniques such as CRISPR-assisted precision breeding Promotes specific prebiotic formulas to ward off adverse effects of antibiotics Covers information on epigenetic regulation in boosting secondary metabolite production and the use of speed breeding combined with high-throughput technologies Proposing a multitude of technologies and methodologies in plant biotechnology with focus on enhancing the production of secondary metabolites and bioactive compounds from medicinal plants, this book is an ideal resource for researchers and academia in plant sciences/breeding, agriculture, and horticulture industries.
Reviews In Ethnopharmacology 2023
DOWNLOAD
Author : Irina Ielciu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-15
Reviews In Ethnopharmacology 2023 written by Irina Ielciu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-15 with Science categories.
Frontiers in Pharmacology is delighted to present the ‘Reviews in Ethnopharmacology: 2023’ series of article collections. Reviews in Ethnopharmacology will publish high-quality scholarly review papers on key topics in Ethnopharmacology. It aims to highlight recent advances in the field, whilst emphasizing important directions and new possibilities for future inquiries. We anticipate the research presented will promote discussion in the Ethnopharmacology community that will translate to best practice applications in clinical, public health and policy settings. The Reviews in Ethnopharmacology: 2023 collection welcomes full-length, mini or systematic review papers. New articles will be added to this collection as they are published. This collection welcomes manuscripts that focus on the following themes: 1. Translational potential of traditional medicinal plants in cancer prevention. 2. Ethnopharmacology of mental health disorders: insights from traditional healing practices and scientific validation. 3. Ethnobotanical approaches for combating antimicrobial resistance. 4. Traditional medicine in the digital age: opportunities and challenges. 5. Herbal medicine and chronic disease management: a global perspective. 6. Ethnopharmacology and sustainable development: balancing conservation and community health. 7. Ethnopharmacology of traditional Chinese medicine: bridging ancient wisdom and modern science. 8. Medicinal plants used in Ayurveda: exploring traditional knowledge and contemporary applications. All the manuscripts submitted to the collection will need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here).). Importantly, we expect an overview on the composition of the preparations used in the pharmacological experiments or a clinical study reviewed. Therefore, we also expect that the MS follow the standards established in the ConPhyMP statement Front. Pharmacol. 13:953205.
Biotechnology And Drug Development For Targeting Human Diseases
DOWNLOAD
Author : Israel Valencia Quiroz
language : en
Publisher: Bentham Science Publishers
Release Date : 2024-03-14
Biotechnology And Drug Development For Targeting Human Diseases written by Israel Valencia Quiroz and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-14 with Science categories.
Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource. Readership Students and professionals in the fields of biotechnology and pharmacology.
Beyond Borders Exploring Diverse Roles Of Heterocyclic Compounds In Combatting Infections And Cancer
DOWNLOAD
Author : Afzal Basha Shaik
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-01
Beyond Borders Exploring Diverse Roles Of Heterocyclic Compounds In Combatting Infections And Cancer written by Afzal Basha Shaik and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-01 with Science categories.
There is an urgent need for the discovery of new drugs against infectious diseases and cancer. Globally, infectious diseases are prevalent, with pathogens constantly evolving, leading to a rise in drug-resistant strains. This necessitates the development of new antimicrobial agents capable of overcoming resistance. Moreover, the COVID-19 pandemic highlighted the critical need for rapid drug development against emerging infectious diseases. Cancer, a leading cause of death worldwide, presents challenges due to its complexity and diversity, and the unique genetic profiles of patients. The American Cancer Society notes increasing cancer rates, underscoring the need for more effective, targeted therapies. In this context, heterocyclic compounds in natural and medicinal chemistry are promising for their structural diversity and reactivity, showing potential in treating infections and cancer by targeting specific cell lines and pathways. This Research Topic focuses on the advancements and applications of heterocyclic compounds, emphasizing their significance in modern medicinal chemistry. The goal is to delve into the multifaceted applications of heterocyclic compounds in addressing two of the most pressing health challenges: infectious diseases and cancer. The core issue this research addresses is the increasing resistance to traditional treatments in infectious diseases and the intricacies of cancer treatment, complicated by its genetic diversity and adaptability. To tackle these issues, this Research Topic aims to gather and showcase cutting-edge research on the isolation, design, synthesis, and application of heterocyclic compounds. Heterocyclic compounds are known for their structural diversity and unique biological properties, offering promising avenues for developing novel therapeutics. Recent advances in this field have demonstrated the potential of heterocyclic compounds to produce more targeted and effective treatments with fewer side effects. By collating research on novel heterocyclic compounds, their mechanisms of action, and their clinical applications, this Research Topic seeks to contribute to the development of next-generation drugs. It aims to foster a deeper understanding of how these compounds interact with biological systems, overcome resistance mechanisms in pathogens, and target specific pathways in cancer cells. The ultimate aim is to advance medicinal chemistry and pharmacology, leading to novel treatments for infectious diseases and cancer. This Research Topic aims to collect important advancements made in the field of medicinal and natural product chemistry including the isolation, design, synthesis and applications of potential heterocyclic compounds as potential anti-infective and anticancer agents. We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to: • Heterocyclic compounds with potential anti-infective and anticancer properties. • Bioactivity-guided isolation and characterization of heterocyclic secondary metabolites from natural sources with potential anti-infective and anticancer properties. • Semi-synthesis and characterization of novel heterocyclic compounds with significant anti-infective and anticancer activity. • Design and synthesis of promising anti-infective and anticancer lead molecules using medicinal, synthetic and computational chemistry approaches.
Comprehensive Toxicology
DOWNLOAD
Author :
language : en
Publisher: Elsevier
Release Date : 2017-12-01
Comprehensive Toxicology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Science categories.
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Exploring The Impact Of Genetics On New Drugs And Potential Drug Targets A Multi Omics Approach To Improve Personalized Therapeutics
DOWNLOAD
Author : Shaoqiu Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-08
Exploring The Impact Of Genetics On New Drugs And Potential Drug Targets A Multi Omics Approach To Improve Personalized Therapeutics written by Shaoqiu Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-08 with Science categories.
In recent years, significant advancements have been made in the field of new drug development. With the advent of high-throughput sequencing technologies, the identification of new drug targets has become more efficient and precise. In addition, multi-omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, have emerged as a powerful tool for understanding the complexity of diseases and identifying new therapeutic targets.
Drug Repurposing In Cancer Therapy
DOWNLOAD
Author : Kenneth K.W. To
language : en
Publisher: Academic Press
Release Date : 2020-07-29
Drug Repurposing In Cancer Therapy written by Kenneth K.W. To and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-29 with Science categories.
Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. - Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research - Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences - Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types