Multiple Sclerosis And Cns Inflammatory Disorders
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Multiple Sclerosis And Cns Inflammatory Disorders
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Author : Lawrence M. Samkoff
language : en
Publisher: John Wiley & Sons
Release Date : 2014-07-14
Multiple Sclerosis And Cns Inflammatory Disorders written by Lawrence M. Samkoff and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-14 with Medical categories.
Multiple Sclerosis and CNS Inflammatory Disorders is a practical guide to effective care of patients with multiple sclerosis and other neuroimmunologic and CNS inflammatory disorders. It provides the scientific basis of multiple sclerosis including etiology, epidemiology, and pathogenesis. It covers the diagnostic process, the course of the disease and prognosis, and the use of MRI in diagnosis and disease monitoring. Disease-modifying treatment algorithms for relapsing-remitting multiple sclerosis, switching therapy, and progressive multiple sclerosis treatment algorithms are all discussed in detail. It also addresses multiple sclerosis in childhood and pregnancy and includes assessment of alternative therapies. This new addition to the Neurology in Practice series contains practical guidance and learning features: • Algorithms and guidelines • “Tips and Tricks” boxes on improving outcomes • “Caution” warning boxes to avoiding problems • “Science Revisited”—quick reminders of the basic science principles necessary for understanding Multiple Sclerosis and CNS Inflammatory Disorders is an ideal reference for neurologists in practice and training.
Inflammatory Disorders Of The Nervous System
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Author : Alireza Minagar
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28
Inflammatory Disorders Of The Nervous System written by Alireza Minagar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.
A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.
Multiple Sclerosis An Issue Of Neurologic Clinics
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Author : Darin T. Okuda
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-11-27
Multiple Sclerosis An Issue Of Neurologic Clinics written by Darin T. Okuda and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-27 with Medical categories.
This issue of Neurologic Clinics, edited by Dr. Darin T. Okuda, focuses on Multiple Sclerosis. Topics include, but are not limited to, Myelin and Axonal Repair Strategies in Multiple Sclerosis; Common Clinical and Imaging Conditions Misdiagnosed as Multiple Sclerosis; Topographical Model for Multiple Sclerosis: A Novel Approach to Understanding Clinical Phenotypes and Disease Activity; Incidental Anomalies Characteristic of CNS Demyelination: Radiologically Isolated Syndrome; Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management; Progressive Forms of Multiple Sclerosis: Distinct Entity or Time Dependent Phenomena; Advanced Symptom Management Strategies in Multiple Sclerosis, Ethnic Considerations and Multiple Sclerosis Disease Variability; The Dynamics of the Gut Microbiome in Multiple Sclerosis in Relation to Disease; Spinal Cord Imaging in Relation to Clinical Status in Multiple Sclerosis, and more.
Targeting The Il 17 Pathway In Inflammatory Disorders
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Author : Cong-Qiu Chu
language : en
Publisher: Springer
Release Date : 2016-11-26
Targeting The Il 17 Pathway In Inflammatory Disorders written by Cong-Qiu Chu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-26 with Medical categories.
This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.
Innate Immune Responses In Cns Inflammation
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Author : Mireia Guerau-de-Arellano
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-30
Innate Immune Responses In Cns Inflammation written by Mireia Guerau-de-Arellano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.
Multiple Sclerosis And Related Disorders
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Author : Douglas S. Goodin
language : en
Publisher: Elsevier
Release Date : 2014-02-05
Multiple Sclerosis And Related Disorders written by Douglas S. Goodin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-05 with Medical categories.
Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. - A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis - Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options - Each chapter is translational and focuses on current research and impact on diagnosis and treatment options
Multiple Sclerosis And Related Disorders Challenges And Approaches To Mechanisms Biomarkers And Therapeutic Targets
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Author : Jinzhou Feng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-05-28
Multiple Sclerosis And Related Disorders Challenges And Approaches To Mechanisms Biomarkers And Therapeutic Targets written by Jinzhou Feng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-28 with Medical categories.
Multiple sclerosis (MS) is an autoimmune condition that causes inflammatory damage to the central nervous system. The pathologic features are diffuse and focal inflammation, demyelination, gliosis, and neuronal damage in the optic nerves, brain, and spinal cord. Multiple sclerosis remains a challenging and disabling disease. There is a greater understanding of the underlying genetic and environmental factors driving the disorder, including low vitamin D levels, smoking, and obesity. Early and accurate diagnosis is essential and needs to be supported by diagnostic criteria, including imaging and spinal fluid abnormalities in patients with clinically isolated syndromes. Other demyelinating diseases are neuromyelitis optica spectrum disorders (NMOSD), anti-myelin oligodendrocyte glycoprotein antibody disease (MOGAD), and acute disseminated encephalomyelitis (ADEM).
Targeted Therapy For The Central Nervous System
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Author : Viral Patel
language : en
Publisher: Elsevier
Release Date : 2024-10-07
Targeted Therapy For The Central Nervous System written by Viral Patel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-07 with Medical categories.
Targeted Therapy for the Central Nervous System: Formulation, Clinical Challenges, and Regulatory Strategies presents research on various delivery methods of drugs to the central nervous system and brain. This volume examines targeted therapies for neurodegenerative disorders and succinctly outlines the future of drug delivery systems, highlighting significant advancements specifically relating to central nervous system delivery. This book will be of great interest to researchers working in the field of neuroscience and pharmacology as well as clinicians (pharmacists, radiologists, psychiatrists). - Provides a current, thorough means on how drugs are delivered to the neurological system - Figures a connection amongst the physiology of drug delivery pertaining to the central nervous system, fundamentals of drug delivery, and distribution principles - Gives an accounting of clinical trials and regulatory approaches for the formulations targeting brain
Motor Disorders
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Author : David S. Younger
language : en
Publisher: Rothstein Publishing
Release Date : 2014-10
Motor Disorders written by David S. Younger and has been published by Rothstein Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10 with Medical categories.
Preeminent Neurology text extensively updated/expanded by 70 leading authorities,providing encyclopedic summary of scientific advances/new clinical practices; aiding in evaluation, diagnosis, and treatment of various motor disorders; and giving...
Neuropsychiatric Manifestations In Neurological Diseases
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Author : Jong S. Kim
language : en
Publisher: Springer Nature
Release Date : 2024-04-22
Neuropsychiatric Manifestations In Neurological Diseases written by Jong S. Kim and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-22 with Medical categories.
Psychiatric symptoms (or mood/emotional disturbances) are diverse in patients with neurological diseases, that include depression, anxiety, emotional incontinence, anger, fatigue, and apathy. These symptoms are common; more than 1/3 of the patients suffer from these symptoms. Unfortunately, they have been neglected because 1) unlike other neurological symptoms such as motor dysfunction, speech disturbances or visual field defect, these symptoms are not visible and difficult to be noticed unless they are specifically examined by a physician who is properly educated on this problem 2) they are often not regarded as neurological symptoms either by the patients or their caregivers 3) they are relatively poorly studied by both neurologists and psychiatrists, and accordingly, are unfamiliar to the physicians. Especially, although `depression’ is well known to physicians, other symptoms such as emotional incontinence, anger, fatigue or apathy are not appropriately assessed by physicians, and frequently misdiagnosed as depression. Moreover, there are difficulties in diagnosing depression in patients neurological diseases. For example, the individual items included in depression diagnosis such as sleep disturbances, appetite loss, or fatigue can result from neurological diseases or comorbid physical conditions in patients with neurological diseases. Therefore, a diagnosis of `depression’ should be made cautiously. Finally, it should be understood that the importance of different mood/ emotional syndromes differ among various neurological diseases; for instance, although emotional incontinence and anger occur in as many as 20-30 % of stroke patients, apathy and fatigue are more important symptoms than these for patients with neuro-degenerative disease. In clinical practice, recognizing these symptoms is important because they negatively affect the patients’ quality of life, impair the functional recovery, increase the mortality, and increase the caregiver burden. Nevertheless, unlike other neurological symptoms such as motor/sensory dysfunction, and speech disturbances, they are relatively well managed mostly by pharmacological therapy such as selective serotonin re-uptake inhibitors (SSRI). The phenomenology of these neuropsychiatric symptoms and related factors, pathophysiological mechanism, and treatment strategies should be properly educated for neurologists, psychiatrists and other physicians. The book is written by experts in this field to disseminate important knowledges to neurologists, psychiatrists, psychologists and other physicians and will eventually benefit patients with neurological diseases.