Multiscale Models In Mechano And Tumor Biology

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Multiscale Models In Mechano And Tumor Biology

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Author : Alf Gerisch
language : en
Publisher: Springer
Release Date : 2018-03-16

Multiscale Models In Mechano And Tumor Biology written by Alf Gerisch and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-16 with Mathematics categories.

This book presents and discusses the state of the art and future perspectives in mathematical modeling and homogenization techniques with the focus on addressing key physiological issues in the context of multiphase healthy and malignant biological materials. The highly interdisciplinary content brings together contributions from scientists with complementary areas of expertise, such as pure and applied mathematicians, engineers, and biophysicists. The book also features the lecture notes from a half-day introductory course on asymptotic homogenization. These notes are suitable for undergraduate mathematics or physics students, while the other chapters are aimed at graduate students and researchers.

Multiscale Modeling In Biomechanics And Mechanobiology

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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10

Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

The Mathematics Of Mechanobiology

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Author : Antonio DeSimone
language : en
Publisher: Springer Nature
Release Date : 2020-06-29

The Mathematics Of Mechanobiology written by Antonio DeSimone and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-29 with Mathematics categories.

This book presents the state of the art in mathematical research on modelling the mechanics of biological systems – a science at the intersection between biology, mechanics and mathematics known as mechanobiology. The book gathers comprehensive surveys of the most significant areas of mechanobiology: cell motility and locomotion by shape control (Antonio DeSimone); models of cell motion and tissue growth (Benoît Perthame); numerical simulation of cardiac electromechanics (Alfio Quarteroni); and power-stroke-driven muscle contraction (Lev Truskinovsky). Each section is self-contained in terms of the biomechanical background, and the content is accessible to all readers with a basic understanding of differential equations and numerical analysis. The book disentangles the phenomenological complexity of the biomechanical problems, while at the same time addressing the mathematical complexity with invaluable clarity. The book is intended for a wide audience, in particular graduate students and applied mathematicians interested in entering this fascinating field.

Constitutive Modelling Of Solid Continua

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Author : José Merodio
language : en
Publisher: Springer Nature
Release Date : 2019-11-14

Constitutive Modelling Of Solid Continua written by José Merodio and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Science categories.

This volume consists of a collection of chapters by recognized experts to provide a comprehensive fundamental theoretical continuum treatment of constitutive laws used for modelling the mechanical and coupled-field properties of various types of solid materials. It covers the main types of solid material behaviour, including isotropic and anisotropic nonlinear elasticity, implicit theories, viscoelasticity, plasticity, electro- and magneto-mechanical interactions, growth, damage, thermomechanics, poroelasticity, composites and homogenization. The volume provides a general framework for research in a wide range of applications involving the deformation of solid materials. It will be of considerable benefit to both established and early career researchers concerned with fundamental theory in solid mechanics and its applications by collecting diverse material in a single volume. The readership ranges from beginning graduate students to senior researchers in academia and industry.

Dune The Distributed And Unified Numerics Environment

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Author : Oliver Sander
language : en
Publisher: Springer Nature
Release Date : 2020-12-07

Dune The Distributed And Unified Numerics Environment written by Oliver Sander and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Computers categories.

The Distributed and Unified Numerics Environment (Dune) is a set of open-source C++ libraries for the implementation of finite element and finite volume methods. Over the last 15 years it has become one of the most commonly used libraries for the implementation of new, efficient simulation methods in science and engineering. Describing the main Dune libraries in detail, this book covers access to core features like grids, shape functions, and linear algebra, but also higher-level topics like function space bases and assemblers. It includes extensive information on programmer interfaces, together with a wealth of completed examples that illustrate how these interfaces are used in practice. After having read the book, readers will be prepared to write their own advanced finite element simulators, tapping the power of Dune to do so.

Multi Scale Extracellular Matrix Mechanics And Mechanobiology

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Author : Yanhang Zhang
language : en
Publisher: Springer
Release Date : 2019-07-12

Multi Scale Extracellular Matrix Mechanics And Mechanobiology written by Yanhang Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-12 with Technology & Engineering categories.

This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation

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Author : Jerome Noailly
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-11

Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation written by Jerome Noailly and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-11 with Science categories.

Leveraging Distortions

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Author : Collin Rice
language : en
Publisher: MIT Press
Release Date : 2021-08-17

Leveraging Distortions written by Collin Rice and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Science categories.

An examination of how scientists deliberately and justifiably use pervasive distortions of relevant features to explain and understand natural phenomena. A fundamental rule of logic is that in order for an argument to provide good reasons for its conclusion, the premises of the argument must be true. In this book, Collin Rice shows how the practice of science repeatedly, pervasively, and deliberately violates this principle. Rice argues that scientists strategically use distortions that misrepresent relevant features of natural phenomena in order to explain and understand--and that they use these distortions deliberately and justifiably in order to discover truths that would be otherwise inaccessible. Countering the standard emphasis on causation, accurate representation, and decomposition of science into its accurate and inaccurate parts, Rice shows that science's epistemic achievements can still be factive despite their being produced through the use of holistically distorted scientific representations. Indeed, he argues, this distortion is one of the most widely employed and fruitful tools used in scientific theorizing. Marshalling a range of case studies, Rice contends that many explanations in science are noncausal, and he presents an alternate view of explanation that captures the variety of noncausal explanations found across the sciences. He proposes an alternative holistic distortion view of idealized models, connecting it to physicists' concept of a universality class; shows how universality classes can overcome some of the challenges of multiscale modeling; and offers accounts of explanation, idealization, modeling, and understanding.

Mechanobiology

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Author : Glen L. Niebur
language : en
Publisher: Elsevier
Release Date : 2019-12-01

Mechanobiology written by Glen L. Niebur and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-01 with Science categories.

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena

Encyclopedia Of Biomedical Engineering

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Author :
language : en
Publisher: Elsevier
Release Date : 2018-09-01

Encyclopedia Of Biomedical Engineering written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-01 with Science categories.

Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field