Multiscale Models In Mechano And Tumor Biology
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Multiscale Models In Mechano And Tumor Biology
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Author : Alf Gerisch
language : en
Publisher: Springer
Release Date : 2018-03-16
Multiscale Models In Mechano And Tumor Biology written by Alf Gerisch and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-16 with Mathematics categories.
This book presents and discusses the state of the art and future perspectives in mathematical modeling and homogenization techniques with the focus on addressing key physiological issues in the context of multiphase healthy and malignant biological materials. The highly interdisciplinary content brings together contributions from scientists with complementary areas of expertise, such as pure and applied mathematicians, engineers, and biophysicists. The book also features the lecture notes from a half-day introductory course on asymptotic homogenization. These notes are suitable for undergraduate mathematics or physics students, while the other chapters are aimed at graduate students and researchers.
Multiscale Modeling In Biomechanics And Mechanobiology
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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10
Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.
Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.
Multiscale Modeling Of Cancer
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Author : Vittorio Cristini
language : en
Publisher: Cambridge University Press
Release Date : 2010-09-09
Multiscale Modeling Of Cancer written by Vittorio Cristini and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-09 with Technology & Engineering categories.
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
Multiscale Cancer Modeling
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Author : Thomas S. Deisboeck
language : en
Publisher: CRC Press
Release Date : 2010-12-08
Multiscale Cancer Modeling written by Thomas S. Deisboeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-08 with Mathematics categories.
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Multiscale Modelling In Biomedical Engineering
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Author : Dimitrios I. Fotiadis
language : en
Publisher: John Wiley & Sons
Release Date : 2023-06-07
Multiscale Modelling In Biomedical Engineering written by Dimitrios I. Fotiadis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-07 with Science categories.
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.
Cell Mechanics
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Author : Arnaud Chauvière
language : en
Publisher: CRC Press
Release Date : 2010-01-27
Cell Mechanics written by Arnaud Chauvière and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-27 with Mathematics categories.
Ubiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling brings together new insight and research on mechanical, mathematical, physical, and biological approaches for simulating the behavior
The Mathematics Of Mechanobiology
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Author : Antonio DeSimone
language : en
Publisher: Springer Nature
Release Date : 2020-06-29
The Mathematics Of Mechanobiology written by Antonio DeSimone and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-29 with Mathematics categories.
This book presents the state of the art in mathematical research on modelling the mechanics of biological systems – a science at the intersection between biology, mechanics and mathematics known as mechanobiology. The book gathers comprehensive surveys of the most significant areas of mechanobiology: cell motility and locomotion by shape control (Antonio DeSimone); models of cell motion and tissue growth (Benoît Perthame); numerical simulation of cardiac electromechanics (Alfio Quarteroni); and power-stroke-driven muscle contraction (Lev Truskinovsky). Each section is self-contained in terms of the biomechanical background, and the content is accessible to all readers with a basic understanding of differential equations and numerical analysis. The book disentangles the phenomenological complexity of the biomechanical problems, while at the same time addressing the mathematical complexity with invaluable clarity. The book is intended for a wide audience, in particular graduate students and applied mathematicians interested in entering this fascinating field.
Multiscale Modeling Of Developmental Systems
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Author :
language : en
Publisher: Academic Press
Release Date : 2007-12-18
Multiscale Modeling Of Developmental Systems written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-18 with Science categories.
Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as molecular biology and population biology) in making use of quantitative modeling to further biological understanding. This volume comprises work that is among the best developmental modeling available and we feel it will do much to remedy this situation. This book is aimed at all those with an interest in the interdisciplinary field of computer and mathematical modeling of multi-cellular and developmental systems. It is also a goal of the Editors to attract more developmental biologists to consider integrating modeling components into their research. Most importantly, this book is intended to serve as a portal into this research area for younger scientists – especially graduate students and post-docs, from both biological and quantitative backgrounds. * Articles written by leading exponents in the field * Provides techniques to address multiscale modeling * Coverage includes a wide spectrum of modeling approaches * Includes descriptions of the most recent advances in the field
Modelling And Computational Approaches For Multi Scale Phenomena In Cancer Research From Cancer Evolution To Cancer Treatment
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Author : Raluca Eftimie
language : en
Publisher: World Scientific Publishing Europe Limited
Release Date : 2024-06-14
Modelling And Computational Approaches For Multi Scale Phenomena In Cancer Research From Cancer Evolution To Cancer Treatment written by Raluca Eftimie and has been published by World Scientific Publishing Europe Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-14 with Mathematics categories.
Cancer development and progression is the result of biological phenomena that occur across multiple temporal and spatial scales. Recent years have seen a flurry of multi-scale mathematical models developed to generate and test new biological hypotheses related to cancer development, progression, and various treatment approaches. This led to the development of new computational and analytical approaches aimed at investigating these multiscale models.This review volume summarises some of the current state of the art related to the modelling, experimental investigation and data assimilation for multiscale phenomena during cancer development, evolution and treatment, as well as computational and analytical investigation of the multi-scale models developed to reproduce the biological phenomena. The book also identifies the experimental and theoretical open problems that will have to be addressed in the near future in order to advance this field. Modelling and Computational Approaches for Multi-scale Phenomena in Cancer Research is an excellent resource for both early career and advanced researchers.
Constitutive Modelling Of Solid Continua
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Author : José Merodio
language : en
Publisher: Springer Nature
Release Date : 2019-11-14
Constitutive Modelling Of Solid Continua written by José Merodio and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Science categories.
This volume consists of a collection of chapters by recognized experts to provide a comprehensive fundamental theoretical continuum treatment of constitutive laws used for modelling the mechanical and coupled-field properties of various types of solid materials. It covers the main types of solid material behaviour, including isotropic and anisotropic nonlinear elasticity, implicit theories, viscoelasticity, plasticity, electro- and magneto-mechanical interactions, growth, damage, thermomechanics, poroelasticity, composites and homogenization. The volume provides a general framework for research in a wide range of applications involving the deformation of solid materials. It will be of considerable benefit to both established and early career researchers concerned with fundamental theory in solid mechanics and its applications by collecting diverse material in a single volume. The readership ranges from beginning graduate students to senior researchers in academia and industry.