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Neurodegenerative Diseases From Gut Brain Axis To Brain Microbiome


Neurodegenerative Diseases From Gut Brain Axis To Brain Microbiome
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Neurodegenerative Diseases From Gut Brain Axis To Brain Microbiome


Neurodegenerative Diseases From Gut Brain Axis To Brain Microbiome
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Author : George Tetz
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-08

Neurodegenerative Diseases From Gut Brain Axis To Brain Microbiome written by George Tetz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-08 with Science categories.


While there are growing line of evidence for the role of the gut microbiome in different neurodegenerative diseases, the role and even the existence of the brain microbiome is only starting to be uncovered. Indeed, the brain was long considered to be a sterile environment and only recent studies have shown the presence of bacteria and fungi in the human central nervous system, and even inhabiting brain cells. The so called “brain microbiome” is appealing and immediately drew attention, since it is highly possible that microorganisms could have profound direct effects on a variety of processes in the brain, with the non-limiting examples of neurodegenerative and neurodevelopmental diseases triggering and progression. However, the brain microbiome remains poorly understood and even despite recent technological advances, is has only began to be explored.



Gut Microbiome In Neurological Health And Disorders


Gut Microbiome In Neurological Health And Disorders
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Author : Amit Kumar Tripathi
language : en
Publisher: Springer Nature
Release Date : 2022-08-03

Gut Microbiome In Neurological Health And Disorders written by Amit Kumar Tripathi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.


This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.



Gut Microbiota In Neurologic And Visceral Diseases


Gut Microbiota In Neurologic And Visceral Diseases
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Author : Tahira Farooqui
language : en
Publisher: Academic Press
Release Date : 2021-03-11

Gut Microbiota In Neurologic And Visceral Diseases written by Tahira Farooqui and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-11 with Medical categories.


Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer's disease, Parkinson's, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. - Reviews the relationship between gut microbiome, diseases and disorders - Discusses the relationship between diet, microbiota and inflammation - Includes neurodegenerative, neuropsychiatric and cardiovascular disorders - Covers diabetes, obesity and metabolic disorders - Identifies molecular mechanisms and signal transduction processes - Encompasses dietary fiber, fat, prebiotics and probiotics



Neurodegenerative Diseases


Neurodegenerative Diseases
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Author : Sachchida Nand Rai
language : en
Publisher: CRC Press
Release Date : 2024-12-02

Neurodegenerative Diseases written by Sachchida Nand Rai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-02 with Science categories.


This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid approaches in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modeling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases. This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches. Key Features: Provides a comprehensive overview of neurodegenerative diseases and their models Examines the limitations associated with modeling neurodegenerative diseases Presents novel treatment strategies for Alzheimer's disease using cellular models Reviews importance of 3D organoid models for therapeutic approaches in Parkinson's disease Covers modeling techniques in understanding prion diseases Explores the role of genetic models in understanding Huntington's disease





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Author :
language : en
Publisher: BoD – Books on Demand
Release Date :

written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Neuroinflammation And Neurodegenerative Diseases


Neuroinflammation And Neurodegenerative Diseases
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Author : Pradeep Kumar
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-27

Neuroinflammation And Neurodegenerative Diseases written by Pradeep Kumar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-27 with Science categories.


Neuroinflammation is a crucial area of study that has garnered increasing attention in recent years due to its implications in various neurodegenerative conditions, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis. This Research Topic aims to delve into the intricate relationship between neuroinflammation and the pathogenesis of these neurodegenerative diseases, with a primary focus on identifying novel therapeutic interventions that could mitigate or halt disease progression. Despite considerable research progress in the field of neurodegenerative diseases, the exact underlying mechanisms and triggers remain partially understood. There is mounting evidence suggesting that neuroinflammation plays a critical role in the development and progression of these disorders. Immune-mediated inflammatory responses within the central nervous system can exacerbate neuronal damage, propagate neurodegeneration, and contribute to disease complexity. Understanding the precise interplay between neuroinflammation and neurodegenerative processes is of utmost importance for devising targeted therapies.



Recent Advances In The Treatment Of Neurodegenerative Disorders


Recent Advances In The Treatment Of Neurodegenerative Disorders
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Author : Sachchida Nand Rai
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-04-26

Recent Advances In The Treatment Of Neurodegenerative Disorders written by Sachchida Nand Rai and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-26 with Science categories.


Researchers have tried various effective treatments that prevent the progressive neurodegeneration of neurons within the brain. Parkinson’s disease (PD), Alzheimer’s disease (AD), and Multiple sclerosis (MS) are some of the most common neurodegenerative diseases (NDDs). Recent Advances in the Treatment of Neurodegenerative Disorders provides interesting updates on treatments of these neurological disorders. Ten chapters have been contributed by experts in pharmacology and give a unique perspective to reader on special topics in this area, including the treatment of neurodegenerative treatment of neurodegenerative disease through ayurveda and phytochemicals, the therapeutic role of vitamins in Parkinson’s disease, mushrooms in NDD treatment, MS treatment, ALS treatment and the use of nanoparticles and nano formulations in NDD treatment. This is an informative reference for pharmacologists, medicinal chemists and healthcare professionals (general practitioners and neurologists) seeking updates in the treatment of some common neurodegenerative disorders.



Developing Successful Neuroprotective Treatments For Tbi Translational Approaches Novel Directions Opportunities And Challenges


Developing Successful Neuroprotective Treatments For Tbi Translational Approaches Novel Directions Opportunities And Challenges
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Author : Stefania Mondello
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-03

Developing Successful Neuroprotective Treatments For Tbi Translational Approaches Novel Directions Opportunities And Challenges written by Stefania Mondello and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-03 with categories.




Gut Microbiota And Immunity In Health And Disease Dysbiosis And Eubiosis S Effects On The Human Body


Gut Microbiota And Immunity In Health And Disease Dysbiosis And Eubiosis S Effects On The Human Body
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Author : Payam Behzadi
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-02

Gut Microbiota And Immunity In Health And Disease Dysbiosis And Eubiosis S Effects On The Human Body written by Payam Behzadi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-02 with Medical categories.


The human body gets its balance and homeostasis from the harbored useful microorganisms. Indeed, the human fetus experiences the first microbial exposure within his/her mother’s body. During the post-partum period, an infant gets formed to be inhabited by different types of useful microorganisms, e.g., archaea, bacteria, fungi, and viruses, collectively known as the microbiota. In particular, the evolution of the gut microbiota throughout life appears to play a pivotal role in both health and disease. On the one hand, metabolic regulation, homeostasis, and a strong immune system depend on gut microbiota balance or eubiosis. On the other hand, gut microbiota dysregulation or dysbiosis is observed in many diseases like diabetes, cancers, autoimmune diseases, inflammatory bowel disorders, atherosclerotic cardiovascular diseases, kidney diseases, neurological disorders, e.g., Alzheimer’s and Parkinson’s diseases, mental health disorders, etc. Interestingly, environmental factors and genetics are involved. Therefore, the interconnection between host-microbiota-environments is a fascinating and emerging area of research to understand health and disease.



Genomic Intelligence


Genomic Intelligence
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Author : Sheetanshu Gupta
language : en
Publisher: CRC Press
Release Date : 2024-12-06

Genomic Intelligence written by Sheetanshu Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Science categories.


The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. The subject matter in this book provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental. Print edition not for sale in South Asia (India, Sri Lanka, Nepal, Bangladesh, Pakistan or Bhutan)