Neuroprotection In Brain Ischemia
DOWNLOAD
Battery Reconditioning
Ford Manuals
Download Neuroprotection In Brain Ischemia PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Neuroprotection In Brain Ischemia book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Emerging Strategies In Neuroprotection
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Manangos
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Emerging Strategies In Neuroprotection written by Manangos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Science categories.
SOLOMON H. SNYDER Receptor Research Reaches Neurology: Relevance to Neurodegenerative Diseases and Stroke President George Bush has heralded the 1990s as the decade of the brain, based largely on the rapid escalation of advances in the molecular neuro sciences and the likelihood that these will bear therapeutic fruit before the turn of the century. There is little doubt that the 1970s and 1980s have witnessed more remarkable advances in the molecular neurosciences than all of the preceding hundred years. Identification of receptor sites for drugs and neurotransmitters along with simple, sensitive, and specific means of monitoring them has made it possible to elucidate the mechanism of action for many known drugs and to identify new chemical entities as potential therapeutic agents. At the same time, the numbers of distinct neurotrans mitters have multiplied. Prior to 1970 only the biogenic amines were well accepted as transmitters. The early 1970s witnessed the gradual acceptance of amino acids as major excitatory and inhibitory neurotransmitters. Identification of opiate receptors and the subsequent identification of the enkephalins as their endogenous ligands led to an appreciation of peptides as putative transmitters and the accumulation of as many as a hundred neuropeptides by the decade's end. In the 1980s the revolutions of molecular biology have been applied aggressively to the neurosciences with molecular cloning for neuropeptide precursors, many important neurochemical en zymes, and receptors for numerous transmitters.
Neuroprotection In Brain Ischemia An Update
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : European Stroke Council
language : en
Publisher:
Release Date : 2006
Neuroprotection In Brain Ischemia An Update written by European Stroke Council and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Cerebral ischemia categories.
Brain Hypoxia And Ischemia New Insights Into Neurodegeneration And Neuroprotection
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Natalia N Nalivaeva
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-15
Brain Hypoxia And Ischemia New Insights Into Neurodegeneration And Neuroprotection written by Natalia N Nalivaeva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-15 with categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
The Handbook Of Neuroprotection
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-02-14
The Handbook Of Neuroprotection written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-14 with Medical categories.
Neuroprotection has been placed on a firm scientific basis during the past decade due to an improved understanding of the molecular basis of neurological diseases and the knowledge that treatment of neurological disorders should not be merely symptomatic but preventative against the progression of the underlying disease, as well as regenerative. The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of neurological disorders. Neuroprotective effects of older, established drugs, as well as new drugs in development, are well documented in this detailed volume, featuring the most cutting-edge and innovative methods currently in use. In-depth and authoritative, The Handbook of Neuroprotection features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
Neuroprotection In Brain Hypoxia
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Matilde Otero-Losada
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-30
Neuroprotection In Brain Hypoxia written by Matilde Otero-Losada and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-30 with categories.
Despite compelling preclinical evidence from laboratory models of brain hypoxia suggesting potential neuroprotective strategies, only scattered data are available from clinical studies. A few candidate neuroprotectants have been studied regarding antioxidant, antiapoptotic, anti-excitotoxic, immunomodulatory, and neurotrophic effects. In parallel with clinical innovations, preclinical research initiatives are also identifying new animal models more closely resembling the clinical course and pathology of neurodegenerative diseases. Clarifying the specific mission of the brain cells involved in the damage/repair system in the examined animal models is important to define new therapeutic targets. Following hypoxic damage, detrimental events intermingle with the repairing events in both time- and cellular-dependent fashion. Identifying reliable post-hypoxia brain markers is mandatory to develop potential therapeutic interventions, improving translational research from the experimental observations to the clinical application. A deeper understanding of the precise participation of neurons, glia, and endothelial cells is expected to offer more clues for designing new therapeutic strategies to reduce the current gap among the experimental and the clinical data. One of the main issues should be to study the epigenetic mechanism of neuroprotective agents and their action on the genetic modification induced by hypoxia. Achieving this goal is presumed critical to obtain more conclusive results in patients that by now do not receive appropriate therapy for mitigating the several diseases generated by brain hypoxia. Although a few ongoing studies are evaluating interesting approaches, future research is necessary to come to a novel mechanism of neuroprotection. This book encompasses different chapters conveying the goals and aims of the pertaining research.
Neuroprotective Therapy For Stroke And Ischemic Disease
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Paul A. Lapchak
language : en
Publisher: Springer
Release Date : 2017-01-12
Neuroprotective Therapy For Stroke And Ischemic Disease written by Paul A. Lapchak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-12 with Medical categories.
A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.
Neuroprotection In Brain Ischemia
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author :
language : en
Publisher:
Release Date : 2006
Neuroprotection In Brain Ischemia written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Innate Tolerance In The Cns
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Jeffrey M. Gidday
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-21
Innate Tolerance In The Cns written by Jeffrey M. Gidday and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-21 with Medical categories.
Cerebral preconditioning is a phenomenon wherein a mild insult or stress induces cellular and tissue adaptation or tolerance to a later, severe injury, therefore reflecting the efficacy of endogenous mechanisms of cerebrovascular protection. Initially identified for rapid cardiac protection, preconditioning has expanded to all aspects of CNS protection from ischemia, trauma and potentially neurodegeneration. Many different stimuli or stressors have been identified as preconditioning agents, suggesting a downstream convergence of mechanisms and underscoring the potential for translational application of preconditioning in the clinic. Moreover, the fundamental mechanisms responsible for preconditioning-induced tolerance will help in the design novel pharmacological approaches for neuroprotection. While stroke and many other brain injuries are not predictable, in some populations (e.g., metabolic syndrome, patients undergoing carotid endarterectomy, aneurysm clipping, or with recent TIAs) the risk for stroke is identifiable and significant, and preconditioning may represent a useful strategy for neuroprotection. For unpredictable injuries, post-conditioning the brain – or inducing endogenous protective mechanisms after the initial injury – can also abrogate the extent of injury. Finally, remote pre- and post-conditioning methods have been developed in animals, and are now being tested in clinical trials, wherein a brief, noninjurious stress to a noncerebral tissue (i.e., skeletal muscle) can provide protection to the CNS and thereby allows clinicians the opportunity to circumvent concerns regarding the direct preconditioning of neurological tissues.
Endogenous Neuroprotection
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : Bernhard Schaller
language : en
Publisher: Nova Publishers
Release Date : 2008
Endogenous Neuroprotection written by Bernhard Schaller and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Cerebral anoxia categories.
Endogenous neuoprotection is a phenomenon where a brief episode of ischemia renders the brain resistant against a subsequent longer-asting ischemia event. Experimentally, the author was able to model hypoxic preconditioning in animal model. Increasing knowledge of this endogenous neuroprotectin by ischemic tolerance may help to minimize neuronal damage following ischemic stroke and hypoxic encephalopathy. This book is, therefore, the first overview of this important topic and will certainly influence further investigations in clinical and neuroscience research.
Neuroprotection In Critical Care And Perioperative Medicine
DOWNLOAD
Battery Reconditioning
Ford Manuals
Author : David L. Reich
language : en
Publisher: Oxford University Press
Release Date : 2018
Neuroprotection In Critical Care And Perioperative Medicine written by David L. Reich and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Clinicians caring for patients are challenged by the task of protecting the brain and spinal cord in high-risk situations. These include post-cardiac arrest, critical care settings, and complex procedural and surgical care. This is the first clinical text that comprehensively covers the various types of neural injury encountered in critical care and perioperative contexts, and neuroprotective strategies to optimize clinical outcomes.