New Advances In Gastrointestinal Motility Research
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New Advances In Gastrointestinal Motility Research
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Author : L. K. Cheng
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-01
New Advances In Gastrointestinal Motility Research written by L. K. Cheng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-01 with Medical categories.
Research into gastrointestinal motility has received renewed interest in part due to recent advances in the techniques for measuring the structure and function of gastrointestinal cells, tissue and organs. The integration of this wealth of data into biophysically based computation models can aid in interpretation of experimental and clinical measurements and the refinement of measurement techniques. The contents of this book span multiple scales - from cell, tissue, organ, to whole body and is divided into four broad sections covering: i) gastrointestinal cellular activity and tissue structure; (ii) techniques for measuring, analyzing and visualizing high-resolution extra-cellular recordings; (iii) methods for sensing gastroelectrical activity using non-invasive bio-electro-magnetic fields and for modulating the underlying gastric electrical activity and finally (iv) methods for assessing manometric and videographic motility patterns and the application of these data for predicting the flow and mixing behavior of luminal contents by using computational fluid dynamic techniques. This book aims to provide both an overview of historical and existing research techniques as well as to highlight future directions and challenges for the community as a whole. It will be suitable for clinicians to understand the cellular and biophysical underpinnings of gastric emptying, gastroenterologists, surgeons, bioengineers and all scientists with interests in gastrointestinal motility research.
Evaluation Of Gastrointestinal Motility And Its Disorders
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Author : Uday C. Ghoshal
language : en
Publisher: Springer
Release Date : 2016-10-24
Evaluation Of Gastrointestinal Motility And Its Disorders written by Uday C. Ghoshal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-24 with Medical categories.
This multi-authored book covers most aspects of evaluation of gastrointestinal motility – a field that has been expanding in recent times largely due to advances in diagnostic modalities; coupled with this, new evidences supporting best practices have increased the interest among clinical gastroenterologists, researchers, teachers and trainees in gastrointestinal motility and its disorders. New advances in the field of evaluation of functional bowel diseases and motility disorders, such as high-resolution manometry, 24-h pH impedance monitoring, Bravo capsule pH-metry, barostat, balloon expulsion test, barium and MR defecography, biofeedback, hydrogen breath tests, motility capsule (smartpill) etc. have significantly expanded the scope and outcome of treating these disorders. The chapters have been contributed by a well-conversant group of experts from the global academia, including India, Singapore, Thailand, Korea and Australia, integrating the body of knowledge on evaluation methods with evidence of best practices for the management of motility disorders. A chapter on how to set-up a manometry laboratory provides key information for clinicians and researchers who are planning to start working in this area. With 11 chapters in the book supported with numerous tables, flow charts, schematic diagrams and images, professionals will find it an essential reading.
Mediators And Drugs In Gastrointestinal Motility I
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mediators And Drugs In Gastrointestinal Motility I written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Since the exhaustive Handbook of Physiology (Alimentary Canal, Section 6, Motility) edited by CHARLES F. CODE in 1968, no complete survey of the morphological basis and the physiological control of intestinal motility has been published, in spite of the enormous amount of new data in the literature on this topic. The new techniques and methodologies, the use of electron microscopy, radioimmunoassay and binding techniques, as weIl as ever more sophisticated electrophysiological procedures have made possible areal flood of discoveries in this field. Moreover, the possibility ofnew studies ofthe endocrine cells in biopsies of human intestinal mucosa even during routine endoscopies, has opened new horizons for gastroenterologists and generated a number of important contribu tions to our knowledge of the morphology and physiopathology of the gut. As usual, new discoveries have also revealed both ignorance and many new problems. For tbis reason, although many of the data reported in this volume can be considered as firmly established, others still require confirmation, and the results of new research in this field are awaited with extreme interest. Since advances are occurring so rapidly, even experts in the specific topics need frequent comprehensive reviews. To avoid an excessively large volume, considera tions ofthe pancreas, liver, and biliary system were not included in this Handbook, which, nevertheless, has attempted to off er the reader the essence of more than 1,500 papers.
Evolving Concepts In Gastrointestinal Motility
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Author : MC Champion
language : en
Publisher: Wiley-Blackwell
Release Date : 1996-07-17
Evolving Concepts In Gastrointestinal Motility written by MC Champion and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-17 with Medical categories.
A comprehensive reference text, Evolving Concepts in Gastrointestinal Motility covers the most recent developments in the pathophysiology, diagnosis and treatment of gastrointestinal (GI) motility disorders. The significant advances that have been made in basic and clinical research are described, and their implications for the practice of gastroenterology are also discussed. An international group of acclaimed experts present authoritative reviews of esophageal motility disorders, gastroesophageal reflux disease, gastroparesis, functional dyspepsia, intestinal pseudo-obstruction, irritable bowel syndrome, sphincter of Oddi dysfunction and chronic constipation. Special chapters focus on landmarks in the study of GI motility, our current understanding of visceral sensation and perception, the potential pathogenic role of alterations in GI motility and GI functioning during sleep, and surgical options in treatment. The last chapter considers controversial issues and takes a look at future trends. Evolving Concepts in Gastrointestinal Motility will appeal to both practitioners and researchers in this field, combining both basic and clinical research to give a definitive account of the current state of play.
Gastrointestinal Motility New Directions
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Author : Ronnie Fass
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2006
Gastrointestinal Motility New Directions written by Ronnie Fass and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Gastrointestinal system categories.
The last decade has seen two important opposing trends in the field of GI motility: An increase in new evaluative techniques and a marked decrease in GI trainees' interest in pursuing a career in GI motility. The latter trend, if it continues, will eventually have a negative impact on the former, further compounded by the limited introduction of new motility-related therapeutic modalities. To reconcile these two antagonistic trends, immediate attention by concerned GI societies and organizations is called for. This publication therefore starts with the perspective of the presidents of the World Congress of Gastroenterology and of the American Motility Society on the academic, research and training opportunities in GI motility. Subsequently, information about new clinical and research developments in GI motility and functional bowel disorders is provided: Experts in the field address areas that show promising new developments likely to lead to a better understanding and management of GI motility disorders. This publication will hopefully draw attention to the renaissance that the GI motility field has enjoyed in recent years. At the same time, it is emphasized that the field has reached a critical point in attracting the needed critical mass that will ensure its future.
Gastroparesis
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Author : Richard Mccallum
language : en
Publisher: Academic Press
Release Date : 2020-09-30
Gastroparesis written by Richard Mccallum and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-30 with Science categories.
Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment is a reference book providing a centralized source of data on gastroparesis collected over the last decade. Contents include the pathophysiology, clinical presentation, diagnostic recommendations and treatment options for gastroparesis. The reference is split into broad subsections, with the strategy of first focusing on the key features of the disease and then turning to controversies, recent developments, patient support resources, the spectrum of treatment – including medical and surgical - and future directions. Chapters will include coverage of important topics like autonomic neuropathy, the brain-gut axis, potential pathophysiological advances at the cellular level, diagnostic and therapeutic options specifically targeted at the pylorus, and the evaluation of the female predominance in gastroparesis. This is a must-have resource for scientists looking to find the next step in their research as well as healthcare professionals ranging from Gastroenterologists to Internists, Surgeons, Nutritionists, Psychiatrists, and Psychologists, Residents and Medical Students who struggle with how to optimally take care of their gastroparetic patients. Provides a comprehensive overview of what is known regarding the pathophysiology, clinical presentation, diagnostic considerations and treatment options for gastroparesis Includes key updates made in the last decade, including the progress made by the NIH Gastroparesis Consortium Presents both sides of key controversies in the field, including the debate between classification of gastroparesis versus functional dyspepsia Fully reviews the major advances in pharmacologic agents for therapy, both anti-emetics and prokinetics Extensive update on the "Pyloric Revolution" and our understanding of the pathophysiology of gastroparesis and how the focus on the pylorus has literally transformed our treatment strategy with an emphasis on both surgical and endoscopic advances in addressing pyloric dysfunction
Pediatric Neurogastroenterology
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Author : Christophe Faure
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-21
Pediatric Neurogastroenterology written by Christophe Faure and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-21 with Medical categories.
Neurogastroenterology is devoted to "study the interface of all aspects of the digestive system with the different branches of the nervous system". Over the past 15 years advances in this field has greatly improved our understanding in primary functional and motility disorders in children. Neurogastroenterology has also begun to revolutionize our vision of "organic" diseases like inflammatory bowel disease, obesity, diabetes as well as microbial-host interactions. Major advances have also been achieved during these years in the knowledge of mechanisms of development of the enteric nervous system at the molecular level allowing a better understanding of diseases related to developmental anomalies and opening perspectives to new treatments with stem cells. Pediatric Neurogastroenterology: Gastrointestinal Motility and Functional Disorders in Children is dedicated to report the most accurate and recent knowledge in the field. Written by the world-renown experts, the book covers the field by providing a comprehensive and up-to-date review and practical guide to pediatric gastrointestinal motility and functional disorders for pediatricians, pediatric gastroenterologists, adult gastroenterologists and all professionals involved in the treatment of children with such disorders.
Biomechanics Of The Gastrointestinal Tract
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Author : Hans Gregersen
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-18
Biomechanics Of The Gastrointestinal Tract written by Hans Gregersen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-18 with Medical categories.
Biomechanics of the Gastrointestinal Tract is an up-to-date book for researchers on the study of the mechanical properties and the motor system of the gastrointestinal tract. A well-illustrated book, it provides a comprehensive overview to relevant tissue geometry, morphology and biomechanical theory. Separate chapters cover smooth muscle and nerve function including the application to animal and human studies of motility, symptoms and pain, determination of the true resting state, history-dependent properties, and tissue remodelling in disease. Several methods and diagnostic applications such as determination of in vivo length-tension diagrams and multimodal pain testing are completely new but will undoubtedly be used by many in the future. New non-invasive imaging techniques based on ultrasound, MR- and CT-scanning in combination with balloon distension are emerging as the techniques for future in vivo studies.
Gastrointestinal Motility Disorders
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Author : Henry P. Parkman
language : en
Publisher: W B Saunders Company
Release Date : 2007
Gastrointestinal Motility Disorders written by Henry P. Parkman and has been published by W B Saunders Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
This issue of Gastroenterology Clinics of North America is on Gastrointestinal Motility Disorders. GI motility disorders are common reasons for patients to see gastroenterologists. Knowledge of the pathophysiology, evaluation and treatment of these disorders is important to appropriately care for patients with gastrointestinal motility disorders in clinical practice. The chapters of this issue will discuss key aspects of gastrointestinal motility disorders focusing on how they relate to practicing gastroenterologists and other health care providers. Current knowledge in the area as well as evolving concepts from clinical investigations and translational research from basic sciences will be discussed. The rapid explosion of new technology used in the evaluation of patients will be covered.
Colonic Motility
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Author : Sushil K. Sarna
language : en
Publisher: Biota Publishing
Release Date : 2010-11-01
Colonic Motility written by Sushil K. Sarna and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-01 with Medical categories.
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.