New And Advanced Mechanistic Insights Into The Influences Of The Infant Gut Microbiota On Human Health And Disease
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New And Advanced Mechanistic Insights Into The Influences Of The Infant Gut Microbiota On Human Health And Disease
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Author : Renqiang Yu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-06
New And Advanced Mechanistic Insights Into The Influences Of The Infant Gut Microbiota On Human Health And Disease written by Renqiang Yu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Science categories.
The human intestinal microbiota plays a vital role in human health and nutrition by producing nutrients, preventing colonization of the gut by potentially pathogenic microorganisms, and preserving the host’s health through interactions with the developing immune system. In early life, the gut microbiota dramatically changes through interactions with various environmental factors and the development of immune system, which is a potential determinant of life-long health. Although bacterial colonization could occur prenatally, the first few weeks after birth correspond to critical stages of gut microbiota colonization. The early-life gut microbiota has a long-lasting effect on the development of gut microbiota throughout life. The dysbiosis and early events in colonization of the human gut microbiota are implicated in changes in the gut microbial trajectory, which may result in long-term consequences, including an increased risk of chronic diseases, such as diabetes, obesity, autism, atopic dermatitis, and asthma, later in life.
Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models
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Author : Lifeng Zhu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-07
Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models written by Lifeng Zhu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-07 with Science categories.
The microbiome plays an indispensable role in our health. Pathophysiological alterations in the gut microbiota has been linked with the development and maintenance of non-communicable diseases, such as obesity, cancer, type 2 diabetes mellitus, cardiovascular diseases, and metabolic syndrome. In order to better investigate the interactions between human health/disease and microbiota and given the practical and ethical complexity of performing invasive sampling procedures in human subjects, different types of animal models have been developed and are frequently used to investigate the multiple dynamics of host–microbiome interactions. Due to the similar organ size and similar metabolic characteristics of pigs and humans, pigs are considered to be a more suitable model for basic biomedical research studies and for studying human-related metabolic diseases than rodents. The anatomical characters, physiological traits, genetics and biochemical indices of pigs are similar to what is reported in humans, thus, pig can be used as a model animal to characterize human gut microbiota and for studying several human diseases. The swine intestinal tract harbours trillions of diverse microorganisms, which get involved in regulating host nutrient digestion, energy absorption, and disease development, and is considered to be one of the main model animal of human obesity and disease research. Since the gastrointestinal organs of pigs are closer to humans, we also use pigs as a model for studying the role of functional foods in intestinal pathophysiology and related indicators of the physical barrier, biochemical barrier, immunological barrier and gut microbiota. Pigs are also the best animal models for exploring the mechanisms underlying human nutrient digestion and absorption, metabolism, and disease treatment. Large animal models such as piglets have been also used to study neonatal diet impact on gut, microbiota and immune system. Pigs and piglets are also convenient models for exploring avenues for developing novel microbial therapies. Pigs and piglets represent hence some of the most widely used animal models for studying the impact of microbiota on its host, and for exploring the dynamics of host–gut microbiome interactions and the roles of human gut microbiota in human health and disease development.
Nutrigenomics And Proteomics In Health And Disease
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Author : Martin Kussmann
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-21
Nutrigenomics And Proteomics In Health And Disease written by Martin Kussmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Technology & Engineering categories.
Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe-derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene-nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology-based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included.
Nutraceuticals New Perspectives And Approaches In Human Health And Disease
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Author : Antimo Cutone
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-13
Nutraceuticals New Perspectives And Approaches In Human Health And Disease written by Antimo Cutone and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-13 with Science categories.
The Oral Microbiome Is A Key Factor In Oral And Systemic Health
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Author : Florence Carrouel
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-10
The Oral Microbiome Is A Key Factor In Oral And Systemic Health written by Florence Carrouel and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-10 with Science categories.
Improving The Gut Microbiome Applications Of Fecal Transplantation In Disease
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Author : Angel Lanas
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-09
Improving The Gut Microbiome Applications Of Fecal Transplantation In Disease written by Angel Lanas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-09 with Medical categories.
Handbook Of Obesity Two Volume Set
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Author : George A. Bray
language : en
Publisher: CRC Press
Release Date : 2024-01-09
Handbook Of Obesity Two Volume Set written by George A. Bray and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-09 with Medical categories.
This 2 volume set comprises of the 4th edition of Volume 1 and the 5th edition of Volume 2. The fifth edition of Volume 1 of Handbook of Obesity written by global experts covers the basic science aspects under the broad topic areas of epidemiology, etiology, and pathophysiology of obesity. Divided into 5 sections and detailed in 66 chapters, this edition covers the important advances occurring over the past decades. With a focus on science of obesity and factors participating in the etiology of obesity, this topic is studied from biological, behavioural and environmental perspectives. Volume 1 is structured into 5 parts: Part 1 focuses on the history, definitions, and prevalence of the obesity. It identifies the historical references to excess weight, obesity in art and literature, direct and surrogate measurements of adiposity and obesity related traits, epidemiology of obesity around the globe, and age, sex and ethnic variation completes this part of the volume. Part 2 explains the biological determinants of obesity. It explains the bioenergetics, energy dissipation mechanisms and exposure to experimental overfeeding, genetic and epigenetic evidence, metabolic rates, energy expenditure and energy partitioning, and the evidence on infections and adiposity. Part 3 describes the behavioral determinants of obesity. It deals with chapters related to food, beverages, and ingestive behavior, dealing with smoking, breast-feeding, and sleep duration and pattern, and sedentary behavior, occupational work, and leisure-time physical activity and obesity. Part 4 comprises of chapters explaining the environmental, social, and cultural determinants of obesity. The chapters in this section focus on the role of agriculture and the food industry in the current obesity epidemic, social and economic aspects of obesity, and ethnic and cultural differences and environmental pollutants. Part 5 of this volume discusses the health consequences of obesity. The chapters address important topics such obesity and heart disease, lipoprotein metabolism, insulin resistance and diabetes, metabolic syndrome, cancer, hepatic biology, pulmonary functions, and arthritis and gout, mental health and quality of life, growth and health disorders in pediatric populations, and on bias and discrimination affecting the obese persons. Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of "Precision Medicine", and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and results for preventing obesity, health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment. Part 2 deals with evaluation of overweight patients, approaches for classifying obesity and using this knowledge to evaluate patients, and addressing ethnic and racial considerations in evaluating patients with obesity. Part 3 explains the impact of lifestyle in managing obesity, which include behavioural management, diet, dietary composition, and meal timing, and the effects of physical activity and exercise in weight loss and weight loss maintenance. Part 4 is focused on medications in the management of obesity. This includes drug selection, various classes of drugs, combination of drugs affecting weight loss, effect of herbal agents on weight loss and treatment of obesity in pediatric populations, genetic diseases causing obesity and the role of drugs in treating the dyslipidemias. Part 5 discusses bariatric surgery, its history, procedure and effects in details, and other surgical techniques including electric stimulation of the vagus nerve, gastric balloons, intestinal liners and liposuction.
Reducing Neonatal Infectious Morbidity And Mortality Joining Up Our Thinking
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Author : Christine Elizabeth Jones
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-25
Reducing Neonatal Infectious Morbidity And Mortality Joining Up Our Thinking written by Christine Elizabeth Jones and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-25 with categories.
Interactions Between Bioactive Food Ingredients And Intestinal Microbiota Volume Ii
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Author : Zheng Ruan
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-27
Interactions Between Bioactive Food Ingredients And Intestinal Microbiota Volume Ii written by Zheng Ruan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-27 with Science categories.
This is Volume II of the Research Topic "Interactions between Bioactive Food Ingredients and Intestinal Microbiota". The previous edition can be found here. Numerous microorganisms colonize the gastrointestinal tract playing critical roles concerning digestion and absorption of dietary nutrients and the regulation of important functions, including host metabolism, immunity, and intestinal barrier function. Increasing evidence suggests that food encompassing nutrients and polyphenols are strong drivers shaping the composition and function of the gut microbiota and mediate the host's physiological activities directly or indirectly. However, the mechanisms involved in the interactions between food nutrients/prebiotics, gut microbiota and host health have not been enlightened to a wide extent.
Probiotics And Prebiotics
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Author : Koen Venema
language : en
Publisher: Caister Academic Press Limited
Release Date : 2015
Probiotics And Prebiotics written by Koen Venema and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.
Composed of nearly a thousand different types of microorganisms - some beneficial, others not - the human gut microbiota plays an important role in health and disease. This is due to the presence of probiotic or beneficial microbes, or due to the feeding of prebiotics that stimulate the endogenous beneficial microbes (these promote health by stimulating the immune system, improving the digestion and absorption of nutrients, and inhibiting the growth of pathogens). The notable health benefits of probiotic organisms have prompted much commercial interest, which in turn has led to a plethora of research initiatives in this area. These range from studies to elucidate the efficacy of the various health benefits to analyses of the diet-microbe interaction as a means of modulating the gut microbiota composition. Research in this area is at a very exciting stage. With state-of-the-art commentaries on all aspects of probiotics and prebiotics research, this book provides an authoritative and timely overview of the field. Written by leading international researchers, each chapter affords critical insight to a particular topic, reviews current research, discusses future direction, and stimulates discussion. Topics range from the different microorganisms used as probiotics (lactobacilli, bifidobacteria, yeast, etc.), and the techniques and approaches used (metagenomics, etc.), to the reviews of the clinical and medical aspects. The provision of extensive reference sections positively encourages readers to pursue each subject in greater detail. *** Librarians: ebook available on ProQuest and EBSCO [Subject: Microbiology, Life Science]