Nk Cells And Other Natural Effector Cells
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Nk Cells And Other Natural Effector Cells
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Author : Ronald B. Herberman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Nk Cells And Other Natural Effector Cells written by Ronald B. Herberman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
NK Cells and Other Natural Effector Cells reviews the state of knowledge on NK cells and other natural effector mechanisms. The coverage of immune effector systems ranges from basic studies on their nature, regulation, and mechanisms of action to important practical issues such as their role in host resistance, their modulation by therapeutic intervention, and alterations of their activity in disease. The book is organized into 12 parts. Parts I and II examine the characteristics of NK cells and other natural effector cells, respectively. Part III focuses on the cell lineage of NK and related effector cells, providing evidence for or against T cell lineage, for or against macrophage lineage, and for or against other or separate lineage. Part IV deals with the genetics of natural resistance in the mouse and rat. Part V presents studies on the regulation of cytotoxic activity. Part VI examines the specificity of natural effector cells, covering the nature of target cell structures and the nature of recognition receptors in effector cells. Part VII discusses the cytotoxicity by cultured lymphoid cells while Part VIII turns to the mechanisms of cytotoxicity. Part IX deals with natural cell-mediated reactivity against primary tumor cells and against non-tumor targets. Part X examines NK cell tumors or the presence of NK cells at the site of tumor growth. Part XI presents clinical studies with natural effector cells. Part XII provides evidence for in vivo reactivity of natural effector cells.
Immunobiology Of Natural Killer Cells
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Author : Eva Lotzova
language : en
Publisher: CRC Press
Release Date : 2019-07-23
Immunobiology Of Natural Killer Cells written by Eva Lotzova and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-23 with Health & Fitness categories.
First published in 1986: This book contributes to the advancing knowledge of reads in the field of NK cells, and will be helpful as a teaching device.
Specificity Function And Development Of Nk Cells
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Author : Klas Kärre
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Specificity Function And Development Of Nk Cells written by Klas Kärre and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.
The Second Life Of Natural Killer Nk Cells
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Author : Chiara Romagnani
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-16
The Second Life Of Natural Killer Nk Cells written by Chiara Romagnani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-16 with categories.
Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of “Innate lymphoid cells” (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications.
Natural Cell Mediated Immunity Against Tumors
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Author : Ronald Herberman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Natural Cell Mediated Immunity Against Tumors written by Ronald Herberman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Natural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly a collection of different research contributed by leading laboratories. It also presents a better perspective of how natural mechanisms fit in with and relate to the traditional and more extensively studied components of the immune system. The book starts off with an overview of the contents of the volume – the historical development of the advances in the field of research and the status of knowledge in the subject area. Divided into four major sections, the book consists of a total of 98 chapters. The sections discuss the natural killer cells and related cells and the natural lymphokine production. This book also explains the natural macrophage and granulocyte cytotoxicity. The book will be a helpful reference for students, professionals, and researchers in biology, immunology, biochemistry, microbiology, and other related fields.
Mechanisms Of Cytotoxicity By Nk Cells
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Author : Ronald Herberman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Mechanisms Of Cytotoxicity By Nk Cells written by Ronald Herberman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Health & Fitness categories.
Mechanisms of Cytotoxicity by NK Cells is the resulting book of a workshop focused on the studies that enhance understanding of the basic mechanisms involved in the function and regulation of NK cells. The book presents the status of knowledge of the mechanisms responsible for the cytotoxic effects of NK cells and the regulation of their activity. The text is further divided into five major sections according to the sequence of the workshop sessions. A separate chapter from the sections has been included at the beginning of the book. The introductory chapter clarifies some points in the subject area of NK cells, particularly its definition. The heterogeneity of NK cells is also discussed in this chapter. Then, the book presents the major topics, including the purification and characterization of NK cells and NK target structures and recognition sites. The mechanisms of postrecognition interactions between NK cells and targets; regulation of NK activity and NK cells; and cultured cells with NK-like activity are also discussed. This book will serve as a helpful guide to students and professionals (scientists, researchers, and professors) in the fields of immunology, biology, microbiology, biochemistry, among others.
Natural Killer Cells
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Author : Michael T. Lotze
language : en
Publisher: Academic Press
Release Date : 2009-11-12
Natural Killer Cells written by Michael T. Lotze and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-12 with Medical categories.
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Immunobiology Of Natural Killer Cells
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Author :
language : en
Publisher:
Release Date : 1986
Immunobiology Of Natural Killer Cells written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Cell-mediated cytotoxicity categories.
Natural Killer Cell Protocols
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Author : Kerry S. Campbell
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Natural Killer Cell Protocols written by Kerry S. Campbell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Medical categories.
In Natural Killer Cell Protocols: Cellular and Molecular Methods, Kerry S. Campbell and Marco Colonna have assembled a comprehensive collection of readily reproducible methods designed to study natural killer (NK) cells from the broadest variety of viewpoints. These include not only classic techniques, but also new approaches to standard methods, newly evolved techniques that have become valuable for specific applications, and unique models for manipulating and studying NK cells. Among the advanced methods covered are those for in vitro transendothelial migration, in vivo detection of cells migrating into tumors, immunofluorescence staining of intracellular cytokines, and in vitro NK cell development. Valuable techniques for specific applications include vaccinia virus protein expression, soluble KIR-Fc fusions for HLA class I binding assays, calcium mobilization in cell conjugates, and identification of heterodimeric receptor complexes using cDNA library expression cloning. No less important are accounts of such classic methods as hybrid resistance, ADCC, viral defense, target cell cytotoxicity assays, cloning and culturing, tumor immunotherapy, and generation of HLA class I transfected target cells. Natural Killer Cell Protocols: Cellular and Molecular Methods offers immunologists, cancer researchers, virologists, and cell biologists today's most comprehensive collection of both established and cutting-edge techniques, methods that will contribute significantly to advancing our understanding of this fascinating and critically important class of cells.
Possible Role Of Natural Killer Cells And Other Effector Cells In Immune Surveillance Against Cancer
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Author : Ronald B. Herberman
language : en
Publisher:
Release Date : 1984
Possible Role Of Natural Killer Cells And Other Effector Cells In Immune Surveillance Against Cancer written by Ronald B. Herberman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.