Nmr In Physiology And Biomedicine


Nmr In Physiology And Biomedicine
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Nmr In Physiology And Biomedicine


Nmr In Physiology And Biomedicine
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Author : Robert J. Gillies
language : en
Publisher: Academic Press
Release Date : 2013-10-22

Nmr In Physiology And Biomedicine written by Robert J. Gillies and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


This book provides a comprehensive review of modern nuclear magnetic resonance approaches to biomedical problems in vivo using state-of-the-art techniques. It devotes equal attention to the methods and applications of NMR and addresses the potential of each of the techniques discussed. The volume includes late-breaking areas such as functional imaging, flow imaging, bioreactor spectroscopy, and chemical shift imaging. All chapters are written in a "current concepts" style that renders information accessible to readers at all levels. Contributors are known experts in the field, lending the book an international perspective.



Nmr In Biomedicine


Nmr In Biomedicine
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Author : Eiichi Fukushima
language : en
Publisher: Springer Science & Business Media
Release Date : 1989-01-01

Nmr In Biomedicine written by Eiichi Fukushima and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-01-01 with Science categories.


For scientists in physics, chemistry, biology, engineering, medicine, and other disciplines



Nmr In Biomedicine


Nmr In Biomedicine
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Author :
language : en
Publisher:
Release Date : 1988

Nmr In Biomedicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.




In Vivo Nmr Spectroscopy


In Vivo Nmr Spectroscopy
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Author : Robin A. de Graaf
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-11

In Vivo Nmr Spectroscopy written by Robin A. de Graaf and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-11 with Science categories.


Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.



Protein Nmr


Protein Nmr
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Author : Lawrence Berliner
language : en
Publisher: Springer
Release Date : 2015-08-24

Protein Nmr written by Lawrence Berliner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-24 with Science categories.


This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance assignments can be obtained using a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome. Further topics include the novel applications of Overhauser dynamic nuclear polarization methods (DNP), assessing protein structure, and aspects of solid-state NMR of macroscopically aligned membrane proteins. This book is an ideal resource for students and researchers in the fields of biochemistry, chemistry, and pharmacology and NMR physics. Comprehensive and intuitively structured, this book examines protein NMR and new novel applications that include the latest technological advances. This book also has the features of: • A selection of various applications and cutting-edge advances, such as novel applications of Overhauser dynamic nuclear polarization methods (DNP) and a suite of 2D and 3D NMR experiments and tips on how overlap problems can be overcome • A pedagogical approach to the methodology • Engaging the reader and student with a clear, yet critical presentation of the applications



Nmr Principles And Applications To Biomedical Research


Nmr Principles And Applications To Biomedical Research
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Author : Jay W. Pettegrew
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nmr Principles And Applications To Biomedical Research written by Jay W. Pettegrew and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.


Nuclear magnetic resonance (NMR) is having an enormous liTIpact on biomedical research both at the basic science and clinical levels. In order to appreciate the elegance and power of this technology a historical perspective is in order. In 1924 Pauli suggested that hydrogen nuclei might possess a magnetic IIlOlllent. This was in fact confinned by Rabbi in 1939 who demonstrated that a beam of hydrogen molecules in the presence of a magnetic field could be mutated by radio frequency fields resonating at the Iarmor frequency. 'Ihe first successful NMR experiments in condensed matter were independently conducted in late 1945 by Purcell, Torrey and PoUnd and by Bloch, Hansen and Packard. 'Ihe Purcell group detected proton NMR in solid paraffin and the Bloch group detected proton in liquid water. Bloch and Purcell received the Nobel Prize in physics in 1952 for these observations . Until about 1952, studies of liquids and solids with broad resonance lines dominated the field of NMR. However, the reports of 3 1 P NMR chemical shifts in several corrpounds in 1949 by Khight, of 14 N resonances in several ions by Proctor and Yu in 1950, and of 1 9 F resonances in several corrpounds in 1950 by Dickinson led to the development of high resolution NMR in Itquids. since the molecular motions in liquids result in very narrow lines compared to those in solids, :much smaller chemical shifts could be detected.



Nmr With Biological Macromolecules In Solution


Nmr With Biological Macromolecules In Solution
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Author : Kurt Wüthrich
language : en
Publisher: World Scientific Publishing Company
Release Date : 2021

Nmr With Biological Macromolecules In Solution written by Kurt Wüthrich and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Science categories.


The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.



In Cell Nmr Spectroscopy


In Cell Nmr Spectroscopy
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Author : Yutaka Ito
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-12-09

In Cell Nmr Spectroscopy written by Yutaka Ito and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-09 with Science categories.


In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.



Physiological Nmr Spectroscopy


Physiological Nmr Spectroscopy
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Author : Sheila M. Cohen
language : en
Publisher:
Release Date : 1987

Physiological Nmr Spectroscopy written by Sheila M. Cohen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.




Carbon 13 Nmr Spectroscopy Of Biological Systems


Carbon 13 Nmr Spectroscopy Of Biological Systems
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Author : Nicolau Beckmann
language : en
Publisher: Elsevier
Release Date : 1995-04-06

Carbon 13 Nmr Spectroscopy Of Biological Systems written by Nicolau Beckmann and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-06 with Science categories.


This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine. An interdisciplinary text with emphasis on both 13C NMR methodology and the relevant biological and biomedical issues State-of-the-art 13C NMR techniques are described; Whenever possible, their advantages over other approaches are emphasized The chapters constitute comprehensive reviews and are written by acknowledged experts in their fields Chapters are written in a clear style, and include a large number of illustrations and comprehensive references