Non Coding Rna Mediated Post Transcriptional Regulation In Human Diseases
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Non Coding Rna Mediated Post Transcriptional Regulation In Human Diseases
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Author : Shaveta Kanoria
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-27
Non Coding Rna Mediated Post Transcriptional Regulation In Human Diseases written by Shaveta Kanoria and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-27 with Science categories.
Long Non Coding Rnas In Cancer
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Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2021-06-24
Long Non Coding Rnas In Cancer written by Alfons Navarro and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Medical categories.
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.
Post Transcriptional Regulation Through Long Non Coding Rnas Lncrnas
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Author : Michael Ladomery
language : en
Publisher: MDPI
Release Date : 2021-08-18
Post Transcriptional Regulation Through Long Non Coding Rnas Lncrnas written by Michael Ladomery and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-18 with Science categories.
This book is a collection of eight articles, of which seven are reviews and one is a research paper, that together form a Special Issue that describes the roles that long noncoding RNAs (lncRNA) play in gene regulation at a post-transcriptional level.
Post Transcriptional Gene Regulation In Human Disease
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Author : Buddhi Prakash Jain
language : en
Publisher: Academic Press
Release Date : 2022-08-12
Post Transcriptional Gene Regulation In Human Disease written by Buddhi Prakash Jain and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-12 with Medical categories.
Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail. - Includes full-color imagery illustrating key concepts and post-transcriptional disease processes, as well as descriptions of methods for studying post-transcriptional gene regulation - Presents fundamental knowledge, molecular and biochemical mechanisms, and recent findings in concise and easily understandable formats - Features a summary and conclusion at the end of each chapter
Long Non Coding Rnas In Human Disease
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Author : Kevin V. Morris
language : en
Publisher: Springer
Release Date : 2016-04-13
Long Non Coding Rnas In Human Disease written by Kevin V. Morris and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-13 with Medical categories.
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
Rna Modification And Non Coding Rnas In Human Disease
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Author : Jing Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-14
Rna Modification And Non Coding Rnas In Human Disease written by Jing Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-14 with Science categories.
Long Noncoding Rnas In Plants
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Author : Santosh Kumar Upadhyay
language : en
Publisher: Academic Press
Release Date : 2020-11-13
Long Noncoding Rnas In Plants written by Santosh Kumar Upadhyay and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Science categories.
The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. - Includes the latest advances and research in long noncoding RNAs in plants - Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops - Focuses on the application and uses of long noncoding RNAs
Epigenetics In Human Disease
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Author : Trygve O Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2018-05-18
Epigenetics In Human Disease written by Trygve O Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-18 with Medical categories.
Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders. Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies. - Includes contributions from leading international investigators involved in translational epigenetic research and therapeutic applications - Integrates methods and applications with fundamental chapters on epigenetics in human disease, along with an evaluation of recent clinical breakthroughs - Presents side-by-side coverage of the basis of epigenetic diseases and treatment pathways - Provides a fully revised resource covering current developments, including stem cell epigenetic therapy, the bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and datasets, and more
Bcl 2 Protein Family
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Author : Claudio Hetz
language : en
Publisher: Springer
Release Date : 2014-11-26
Bcl 2 Protein Family written by Claudio Hetz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-26 with Medical categories.
In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‐2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.
Tendons And Ligaments Development Pathogenesis Tissue Engineering And Regenerative Medicine
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Author : Dai Fei Elmer Ker
language : en
Publisher: Frontiers Media SA
Release Date : 2024-09-27
Tendons And Ligaments Development Pathogenesis Tissue Engineering And Regenerative Medicine written by Dai Fei Elmer Ker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-27 with Technology & Engineering categories.
In our rapidly aging society, tendon and ligament injuries pose a tremendous socioeconomic burden with a great impact on mobility and patient quality of life. Understanding tendon/ligament development and maturation, pathogenesis, wound healing, tissue engineering, and regenerative medicine approaches will be crucial. In this collection, we aim to showcase tendon and ligament research that spans the gamut of basic science to pre-clinical translation. These topics include but are not limited to tendon/ligament development and maturation, the pathogenesis of tendon and ligament injury, isolation and modification of stem cells and their products for regenerative medicine, identification and delivery of bioactive tenogenic/ligamentogenic molecules, development and characterization of bioactive and/or mechanically robust biomaterials in silico, in vitro, ex vivo, and in vivo for tissue engineering, as well as the use of novel multidisciplinary methodologies and technologies including systems biology and synthetic biology approaches for studying tendons and ligaments as well as enhancing their repair and regeneration. With this collection, we aim to expose readers to inter- and multi-disciplinary biological and bioengineering techniques and research, which will stimulate broader discussion and advance our understanding to improve tendon/ligament repair and regeneration.