Novel Biomarkers For Clinical And Molecular Stratification Of Organ Involvement In Rheumatic Diseases


Novel Biomarkers For Clinical And Molecular Stratification Of Organ Involvement In Rheumatic Diseases
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Novel Biomarkers For Clinical And Molecular Stratification Of Organ Involvement In Rheumatic Diseases


Novel Biomarkers For Clinical And Molecular Stratification Of Organ Involvement In Rheumatic Diseases
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Author : Xiaolin Sun
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-29

Novel Biomarkers For Clinical And Molecular Stratification Of Organ Involvement In Rheumatic Diseases written by Xiaolin Sun and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Medical categories.




Oxford Textbook Of Rheumatology


Oxford Textbook Of Rheumatology
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Author : Philip Conaghan
language : en
Publisher: Oxford University Press
Release Date : 2013-10

Oxford Textbook Of Rheumatology written by Philip Conaghan and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10 with Medical categories.


A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.



Systemic Sclerosis Recent Advances And New Perspectives


Systemic Sclerosis Recent Advances And New Perspectives
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Author : Katja Perdan Pirkmajer
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-05-15

Systemic Sclerosis Recent Advances And New Perspectives written by Katja Perdan Pirkmajer and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-15 with Medical categories.


Systemic sclerosis (SSc) is a multisystem autoimmune disease involving vasculopathy and immune activation that leads to the deposition of extracellular matrix and the development of fibrosis, resulting in cardinal clinical problems. Systemic Sclerosis - Recent Advances and New Perspectives provides a comprehensive overview of the pathophysiology, diagnosis, and specific management of the clinical manifestations of SSc. The book addresses the current understanding of the causes and consequences of inflammatory activation, chromosomal instability, and activating factors. Special emphasis is placed on diagnosis, from the recognition of very early systemic sclerosis and consideration of its treatment to diagnostic methods for microvascular and pulmonary involvement. It also highlights the less life-threatening but very common manifestations of bone and skeletal muscle involvement, which affect patient quality of life.



Neurodegenerative Diseases


Neurodegenerative Diseases
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Author : Nagehan Ersoy Tunalı
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-01-20

Neurodegenerative Diseases written by Nagehan Ersoy Tunalı and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-20 with Science categories.


Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical correlations, genetic aspects, neuropathological findings, and current therapeutic interventions in neurodegenerative diseases. I believe that this book will enlighten the curiosity for neurodegeneration and also encourage researchers to work on potentially effective molecular therapies for still mysterious neurodegenerative disorders.



Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease


Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-06-25

Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-25 with Medical categories.


Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.



Scleroderma


Scleroderma
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Author : John Varga
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-21

Scleroderma written by John Varga and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-21 with Medical categories.


This essential book examines the most up-to-date information on scleroderma, offering a clear and concise synthesis of current concepts in pathogenesis and modern approaches to management. Presents a multidisciplinary approach to scleroderma care.



Paediatric Rheumatology


Paediatric Rheumatology
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Author : Helen E. Foster
language : en
Publisher: OUP Oxford
Release Date : 2012-06-14

Paediatric Rheumatology written by Helen E. Foster and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-14 with Medical categories.


Paediatric Rheumatology is an indispensible resource for the identification and management of specific rheumatological disorders. As well as covering common and rare rheumatological problems, there are also chapters on investigations and emergencies, designed for quick reference. The handbook includes dedicated topics on systemic diseases affecting rheumatology; the relevant clinical guidelines and information needed for a rheumatologist to successfully management a young patient; and, a coloured section for guidance on rash-related investigations. Paediatric Rheumatology is also fully endorsed by the British Society for Paediatric and Adolescent Rheumatology and the UK Paediatric Rheumatology Clinical Studies Group.



The Heart In Rheumatic Autoimmune And Inflammatory Diseases


The Heart In Rheumatic Autoimmune And Inflammatory Diseases
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Author : Udi Nussinovitch
language : en
Publisher: Academic Press
Release Date : 2017-02-10

The Heart In Rheumatic Autoimmune And Inflammatory Diseases written by Udi Nussinovitch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-10 with Medical categories.


The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.



Biomarker


Biomarker
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Author : Ghousia Begum
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-09-05

Biomarker written by Ghousia Begum and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-05 with Medical categories.


This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.



Skills In Rheumatology


Skills In Rheumatology
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Author : Hani Almoallim
language : en
Publisher: Springer Nature
Release Date : 2021-01-05

Skills In Rheumatology written by Hani Almoallim and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-05 with Medical categories.


This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.