Oecd Guidelines For The Testing Of Chemicals Section 1 Test No 123 Partition Coefficient 1 Octanol Water Slow Stirring Method
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Oecd Guidelines For The Testing Of Chemicals Section 1 Test No 123 Partition Coefficient 1 Octanol Water Slow Stirring Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2022-06-30
Oecd Guidelines For The Testing Of Chemicals Section 1 Test No 123 Partition Coefficient 1 Octanol Water Slow Stirring Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-30 with categories.
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 305 Bioaccumulation In Fish Aqueous And Dietary Exposure
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2012-10-02
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 305 Bioaccumulation In Fish Aqueous And Dietary Exposure written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-02 with categories.
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 319a Determination Of In Vitro Intrinsic Clearance Using Cryopreserved Rainbow Trout Hepatocytes Rt Hep
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 319a Determination Of In Vitro Intrinsic Clearance Using Cryopreserved Rainbow Trout Hepatocytes Rt Hep written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 319b Determination Of In Vitro Intrinsic Clearance Using Rainbow Trout Liver S9 Sub Cellular Fraction Rt S9
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-06-27
Oecd Guidelines For The Testing Of Chemicals Section 3 Test No 319b Determination Of In Vitro Intrinsic Clearance Using Rainbow Trout Liver S9 Sub Cellular Fraction Rt S9 written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-27 with categories.
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Oecd Series On Testing And Assessment Guidance Document On Good In Vitro Method Practices Givimp
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-12-10
Oecd Series On Testing And Assessment Guidance Document On Good In Vitro Method Practices Givimp written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-10 with categories.
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Toxicology Of Fishes
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Author : Kristine L. Willett
language : en
Publisher: CRC Press
Release Date : 2024-03-07
Toxicology Of Fishes written by Kristine L. Willett and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-07 with Science categories.
This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.
Oilfield Chemistry And Its Environmental Impact
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Author : Henry A. Craddock
language : en
Publisher: John Wiley & Sons
Release Date : 2018-05-11
Oilfield Chemistry And Its Environmental Impact written by Henry A. Craddock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-11 with Science categories.
Consolidates the many different chemistries being employed to provide environmentally acceptable products through the upstream oil and gas industry This book discusses the development and application of green chemistry in the oil and gas exploration and production industry over the last 25 years — bringing together the various chemistries that are utilised for creating suitable environmental products. Written by a highly respected consultant to the oil and gas industry — it introduces readers to the principles and development of green chemistry in general, and the regulatory framework specific to the oil and gas sector in the North Sea area and elsewhere in the world. It also explores economic drivers pertaining to the application of green chemistry in the sector. Topics covered in Oilfield Chemistry and its Environmental Impact include polymer chemistry, surfactants and amphiphiles, phosphorus chemistry, inorganic salts, low molecular weight organics, silicon chemistry and green solvents. It also looks at sustainability in an extractive industry, examining the approaches used and the other methodologies that could be applied in the development of better chemistries, along with discussions about where the application of green chemistry is leading in this industry sector. Provides the reader with a ready source of reference when considering what chemistries are appropriate for application to oilfield problems and looking for green chemistry solutions Brings together the pertinent regulations which workers in the field will find useful, alongside the chemistries which meet the regulatory requirements Written by a well-known specialist with a combined knowledge of chemistry, manufacturing procedures and environmental issues Oilfield Chemistry and its Environmental Impact is an excellent book for oil and gas industry professionals as well as scientists, academic researchers, students and policy makers.
Introduction To Toxicological Screening Methods And Good Laboratory Practice
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Author : Saravana Babu Chidambaram
language : en
Publisher: Springer Nature
Release Date : 2022-02-11
Introduction To Toxicological Screening Methods And Good Laboratory Practice written by Saravana Babu Chidambaram and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-11 with Medical categories.
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.
Energetic Materials
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Author : Mark J. Mezger
language : en
Publisher: CRC Press
Release Date : 2017-07-06
Energetic Materials written by Mark J. Mezger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Technology & Engineering categories.
This book will take an in-depth look at the technologies, processes, and capabilities to develop and produce "next generation" energetic materials for both commercial and defense applications, including military, mining operations, oil production and well perforation, and construction demolition. It will serve to highlight the critical technologies, latest developments, and the current capability gaps that serve as barriers to military fielding or transition to the commercial marketplace. It will also explain how the processing technologies can be spun out for use in other non-energetics related industries.
Human And Ecological Risk Assessment
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Author : Dennis J. Paustenbach
language : en
Publisher: John Wiley & Sons
Release Date : 2024-04-15
Human And Ecological Risk Assessment written by Dennis J. Paustenbach and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-15 with Technology & Engineering categories.
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.