Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 493 Performance Based Test Guideline For Human Recombinant Estrogen Receptor Hrer In Vitro Assays To Detect Chemicals With Er Binding Affinity
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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 493 Performance Based Test Guideline For Human Recombinant Estrogen Receptor Hrer In Vitro Assays To Detect Chemicals With Er Binding Affinity
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2024-06-25
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 493 Performance Based Test Guideline For Human Recombinant Estrogen Receptor Hrer In Vitro Assays To Detect Chemicals With Er Binding Affinity written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-25 with categories.
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology for human recombinant in vitro assays to detect substances with estrogen receptor binding affinity (hrER binding assays).
Ecotoxicology Of Nanoparticles In Aquatic Systems
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Author : Julian Blasco
language : en
Publisher: CRC Press
Release Date : 2019-07-19
Ecotoxicology Of Nanoparticles In Aquatic Systems written by Julian Blasco and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-19 with Science categories.
The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.
Reproductive And Developmental Toxicology
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Author : Ramesh C. Gupta
language : en
Publisher: Academic Press
Release Date : 2022-02-11
Reproductive And Developmental Toxicology written by Ramesh C. Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-11 with Medical categories.
**Selected for Doody's Core Titles® 2024 in Toxicology**Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
Animal Models In Research
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Author : Harikrishnan Vijayakumar Sreelatha
language : en
Publisher: Springer Nature
Release Date : 2024-04-03
Animal Models In Research written by Harikrishnan Vijayakumar Sreelatha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-03 with Medical categories.
This book describes the development of animal models widely used in biomedical research using step-wise instructions and photographs. Showcasing a wide range of species from zebra fishes, birds, rodents, rabbits, dogs, and pigs, the book includes detailed methodology on how to work with these species and to develop various models. The animal models in neurology including stroke, Alzheimer’s disease, Parkinson’s disease, and Schizophrenia; Animal models in cancer research, sleep disorders, and cardiovascular diseases are described to meet the understanding of researchers who plan to replicate these models in their laboratories. In depth detailing on the development of targeted gene knockouts and transgenics, implantation models that are used in toxicology studies, and pharmacokinetic studies in pigs and dogs are a highlight. Further, the book describes pharmacologic, chemically induced, surgically induced, microbiologically induced, infectious models, models for neurobehavioral studies, oncology research, and pain research. The book has dedicated sections on anesthesia and analgesia and teaches procedures like venous cut-downs and cannulations in pigs and dogs, and endotracheal intubation, mechanical ventilation and thoracotomy in rodents and will serve as a self-training tool. Concepts in the field of animal model development are explained using examples. Sample size selection, study design, and statistical evaluation of experiments involving laboratory animals are explained to enable young researchers to practically understand the nuances. This book will be a valuable tool for academicians, students, scientists, and veterinarians and will benefit equally who are new to the field and who are already working with laboratory animals.
Comprehensive Toxicology
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Author :
language : en
Publisher: Elsevier
Release Date : 2017-12-01
Comprehensive Toxicology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Science categories.
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Handbook Of Cosmetic Science And Technology
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Author : Frank Dreher
language : en
Publisher: CRC Press
Release Date : 2022-08-11
Handbook Of Cosmetic Science And Technology written by Frank Dreher and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-11 with Medical categories.
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice
Sediment Quality Assessment
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Author : Graeme Batley
language : en
Publisher: CSIRO PUBLISHING
Release Date : 2016-02-01
Sediment Quality Assessment written by Graeme Batley and has been published by CSIRO PUBLISHING this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-01 with Science categories.
Contaminated sediments represent an ongoing threat to the health of aquatic ecosystems. The assessment of sediment quality is, therefore, an important concern for environmental regulators. Sediment quality guidelines are now well established in regulatory frameworks worldwide; however, practical guidance that covers all of the key aspects of sediment quality assessment is not readily available. In 2005, CSIRO published its highly cited Handbook for Sediment Quality Assessment. In the ensuing period, the science has advanced considerably. This practical guide is a revised and much expanded second edition, which will be a valuable tool for environmental practitioners. Written by experts in the field, it provides coverage of: sediment sampling; sample preparation; chemical analysis; ecotoxicology; bioaccumulation; biomarkers; and ecological assessment. In addition, detailed appendices describe protocols for many of the tests to be used.
Treatment Of Micropollutants In Water And Wastewater
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Author : Jurate Virkutyte
language : en
Publisher: IWA Publishing
Release Date : 2010-08-14
Treatment Of Micropollutants In Water And Wastewater written by Jurate Virkutyte and has been published by IWA Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-14 with Science categories.
Over the last few years there has been a growing concern over the increasing concentration of micropollutants originating from a great variety of sources including pharmaceutical, chemical engineering and personal care product industries in rivers, lakes, soil and groundwater. As most of the micropollutants are polar and persistent compounds, they are only partially or not at all removed from wastewater and thus can enter the environment posing a great risk to the biota. It is hypothesized that wastewater is one of the most important point sources for micropollutants. Treatment of Micropollutants in Water and Wastewater gives a comprehensive overview of modern analytical methods and will summarize novel single and hybrid methods to remove continuously emerging contaminants - micropollutants from the aqueous phase. New trends (e.g. sensor technology, nanotechnology and hybrid treatment technologies) are described in detail. The book is very timely because the new techniques are still in the development phase and have to be realized not only in the laboratory but also on a larger scale. The content of the book is divided into chapters that present current descriptive and analytical methods that are available to detect and measure micropollutants together with detailed information on various chemical, biological and physicochemical methods that have evolved over the last few decades. Treatment of Micropollutants in Water and Wastewater will also enable readers to make well informed choices through providing an understanding of why and how micropollutants must be removed from water sources, and what are the most appropriate and available techniques for providing a cost and technologically effective and sustainable solutions for reaching the goal of micropollutant-free water and wastewater. The book will be suitable for water and wastewater professionals as well for students and researchers in civil engineering, environmental engineering and process engineering fields.
Test No 493 Performance Based Test Guideline For Human Recombinant Estrogen Receptor Hrer In Vitro Assays To Detect Chemicals With Er Binding Affinity
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Author :
language : en
Publisher:
Release Date : 2015
Test No 493 Performance Based Test Guideline For Human Recombinant Estrogen Receptor Hrer In Vitro Assays To Detect Chemicals With Er Binding Affinity written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Innovations In Food Technology
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Author : Pragya Mishra
language : en
Publisher: Springer Nature
Release Date : 2020-10-12
Innovations In Food Technology written by Pragya Mishra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.
This book gathers a collection of essays that describe recent innovations in food technology including food processing, packaging, food safety, and novel ingredients. By 2050, the world will face the challenge of having to feed an estimated 9 billion people. In order to meet that challenge, innovations in food research are of the utmost importance. The book is divided into four sections, each of which explores an important aspect like food processing, food microbiology, and nutritional security. Written by respected scholars in the field, the respective chapters discuss a range of new and enhanced food materials, as well as processing innovations to extend shelf life and reduce toxic effects. The book also addresses the health potential of various nutraceuticals, bio-absorption of metals and their positive impacts on living systems, as well as methods for reducing food wastage, preventing the loss of nutritive value, and preserving or enhancing palatability. Given its scope, the book will be highly interesting for food scientists, both in academia and the food industry. It will also benefit advanced graduate students and senior researchers.