Omics Data Integration Towards Mining Of Phenotype Specific Biomarkers In Cancer Volume Ii
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Omics Data Integration Towards Mining Of Phenotype Specific Biomarkers In Cancer Volume Ii
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Author : Liang Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-29
Omics Data Integration Towards Mining Of Phenotype Specific Biomarkers In Cancer Volume Ii written by Liang Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-29 with Science categories.
Omics Data Integration Towards Mining Of Phenotype Specific Biomarkers In Cancers And Diseases
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Author : Liang Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-16
Omics Data Integration Towards Mining Of Phenotype Specific Biomarkers In Cancers And Diseases written by Liang Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-16 with Science categories.
Multi Omic Data Integration In Oncology
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Author : Chiara Romualdi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-03
Multi Omic Data Integration In Oncology written by Chiara Romualdi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-03 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research
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Author : Lixin Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research written by Lixin Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Science categories.
Systems Medicine
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-24
Systems Medicine written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with Science categories.
Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information
Integrative Omics
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Author : Manish Kumar Gupta
language : en
Publisher: Elsevier
Release Date : 2024-05-03
Integrative Omics written by Manish Kumar Gupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-03 with Science categories.
Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic 'step by step' manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. - Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships - Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to 'translational research', i.e., drug discovery, drug target prediction, and precision medicine - Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research Volume Ii
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Author : Lixin Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-05
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research Volume Ii written by Lixin Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-05 with Science categories.
This Research Topic is part of a series with, "Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research - Volume I" (https://www.frontiersin.org/research-topics/13816/bioinformatics-analysis-of-omics-data-for-biomarker-identification-in-clinical-research) The advances and the decreasing cost of omics data enable profiling of disease molecular features at different levels, including bulk tissues, animal models, and single cells. Large volumes of omics data enhance the ability to search for information for preclinical study and provide the opportunity to leverage them to understand disease mechanisms, identify molecular targets for therapy, and detect biomarkers of treatment response. Identification of stable, predictive, and interpretable biomarkers is a significant step towards personalized medicine and therapy. Omics data from genomics, transcriptomics, proteomics, epigenomics, metagenomics, and metabolomics help to determine biomarkers for prognostic and diagnostic applications. Preprocessing of omics data is of vital importance as it aims to eliminate systematic experimental bias and technical variation while preserving biological variation. Dozens of normalization methods for correcting experimental variation and bias in omics data have been developed during the last two decades, while only a few consider the skewness between different sample states, such as the extensive over-repression of genes in cancers. The choice of normalization methods determines the fate of identified biomarkers or molecular signatures. From these considerations, the development of appropriate normalization methods or preprocessing strategies may promote biomarker identification and facilitate clinical decision-making.
Advances In Methods And Tools For Multi Omics Data Analysis
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Author : Ornella Cominetti
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-12
Advances In Methods And Tools For Multi Omics Data Analysis written by Ornella Cominetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-12 with Science categories.
A Complex Systems Approach To Epilepsy
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Author : Rod C. Scott
language : en
Publisher: Cambridge University Press
Release Date : 2023-01-26
A Complex Systems Approach To Epilepsy written by Rod C. Scott and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-26 with Medical categories.
The epilepsies are devastating neurological disorders for which progress developing effective new therapies has slowed over recent decades, primarily due to the complexity of the brain at all scales. This reality has shifted the focus of experimental and clinical practice toward complex systems approaches to overcoming current barriers. Organized by scale from genes to whole brain, the chapters of this book survey the theoretical underpinnings and use of network and dynamical systems approaches to interpreting and modeling experimental and clinical data in epilepsy. The emphasis throughout is on the value of the non-trivial, and often counterintuitive, properties of complex systems, and how to leverage these properties to elaborate mechanisms of epilepsy and develop new therapies. In this essential book, readers will learn key concepts of complex systems theory applied across multiple scales and how each of these scales connects to epilepsy.
Computational Intelligence In Healthcare
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Author : Meenu Gupta
language : en
Publisher: CRC Press
Release Date : 2023-02-10
Computational Intelligence In Healthcare written by Meenu Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-10 with Computers categories.
Computational intelligence (CI) refers to the ability of computers to accomplish tasks that are normally completed by intelligent beings such as humans and animals. Artificial intelligent systems offer great improvement in healthcare systems by providing more intelligent and convenient solutions and services assisted by machine learning, wireless communications, data analytics, cognitive computing, and mobile computing. Modern health treatments are faced with the challenge of acquiring, analysing, and applying the large amount of knowledge necessary to solve complex problems. AI techniques are being effectively used in the field of healthcare systems by extracting the useful information from the vast amounts of data by applying human expertise and CI methods, such as fuzzy models, artificial neural networks, evolutionary algorithms, and probabilistic methods which have recently emerged as promising tools for the development and application of intelligent systems in healthcare practice. This book starts with the fundamentals of computer intelligence and the techniques and procedures associated with them. Contained in the book are state-of-the-art CI methods and other allied techniques used in healthcare systems as well as advances in different CI methods that confront the problem of effective data analysis and storage faced by healthcare institutions. The objective of this book is to provide the latest research related to the healthcare sector to researchers and engineers with a platform encompassing state-of-the-art innovations, research and design, and the implementation of methodologies.