Origins Of Resistance To Toxic Agents
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Origins Of Resistance To Toxic Agents
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Author : M Sevag
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Origins Of Resistance To Toxic Agents written by M Sevag and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Origins of Resistance to Toxic Agents contains the proceedings of the Symposium held in Washington, D.C. on March 25-27, 1954. Contributors theoretically explore the origins of drug resistance and related problems, based on the concept that the development of resistance to various toxic agents is associated with alterations and/or loss in enzyme proteins, and can explain the mutational and other processes. This text is organized into five sections encompassing 25 chapters and begins with an overview of the evolutionary aspects of resistance to antibacterial agents, herbicides, and insecticides. The book then discusses spontaneous and induced mutations to drug resistance in Escherichia coli, along with the mechanism of drug resistance in protozoa and bacteria, the physiological aspects of insect resistance to insecticides, and the enzymatic detoxication of DDT. The next chapters focus on the origins of tolerance and addiction to drugs and the problem of alcoholism; biochemical effects of narcotics and alcohol administration; tolerance and physical dependence to narcotics; and resistance and dependence in cancer cells. The book concludes by analyzing the significance of protein configuration to the specificity of biological interaction. This book is a valuable source of information for physicians, biochemists, pharmacologists, entomologists, plant physiologists, students of cancer, and those who are interested in the theory of the evolution of living matter.
Origins Of Resistance To Toxic Agents
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Author : United States. Office of Naval Research
language : en
Publisher:
Release Date : 1955
Origins Of Resistance To Toxic Agents written by United States. Office of Naval Research and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1955 with Poisons categories.
Antimicrobial Drug Resistance
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Author : Douglas L. Mayers
language : en
Publisher: Springer
Release Date : 2017-06-19
Antimicrobial Drug Resistance written by Douglas L. Mayers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-19 with Medical categories.
The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.
Mechanisms Of Antibiotic Resistance
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Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01
Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Microbial Evolution And Co Adaptation
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2009-05-10
Microbial Evolution And Co Adaptation written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-10 with Science categories.
Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
The Effects On Human Health Of Subtherapeutic Use Of Antimicrobials In Animal Feeds
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1980-02-01
The Effects On Human Health Of Subtherapeutic Use Of Antimicrobials In Animal Feeds written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980-02-01 with Medical categories.
Experimental Chemotherapy
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Author : R. J. Schnitzer
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Experimental Chemotherapy written by R. J. Schnitzer and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Health & Fitness categories.
Experimental Chemotherapy, Volume I, attempts to condense the existing knowledge in the broad field of experimental chemotherapy in a comprehensive form. The arrangement of the subject matter follows a plan by which the not always avoidable repetitive description is reduced to a minimum. In most of the protozoan and metazoan infections it appeared advantageous to discuss the different series of active compounds according to the specific diseases and their causative agents. In other cases, owing to the wide range of activity of certain antibacterials, the material is arranged according to the groups of compounds. This first volume deals with infections caused by parasites, both protozoan and metazoan; it also contains general chapters on history of chemotherapy, toxicology, statistics, and drug resistance. It is hoped that the treatise will be useful to experimental workers engaged in the search for new chemotherapeutic remedies and in the study of their mechanism of action; to all who are involved in the teaching of pharmacology and therapeutics; and to physicians and veterinarians interested in the experimental basis of the drugs they are using.
Advances In Genetics
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Author :
language : en
Publisher: Academic Press
Release Date : 1955-01-01
Advances In Genetics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1955-01-01 with Science categories.
Advances in Genetics
Pyrrhic Progress
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Author : Claas Kirchhelle
language : en
Publisher: Rutgers University Press
Release Date : 2020-01-17
Pyrrhic Progress written by Claas Kirchhelle and has been published by Rutgers University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-17 with Medical categories.
Pyrrhic Progress analyses over half a century of antibiotic use, regulation, and resistance in US and British food production. Mass-introduced after 1945, antibiotics helped revolutionize post-war agriculture. Food producers used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals' growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics. Pyrrhic Progress reconstructs the complicated negotiations that accompanied this process of risk prioritization between consumers, farmers, and regulators on both sides of the Atlantic. Unsurprisingly, solutions differed: while Europeans implemented precautionary antibiotic restrictions to curb AMR, consumer concerns and cost-benefit assessments made US regulators focus on curbing drug residues in food. The result was a growing divergence of antibiotic stewardship and a rise of AMR. Kirchhelle's comprehensive analysis of evolving non-human antibiotic use and the historical complexities of antibiotic stewardship provides important insights for current debates on the global burden of AMR.
Drug Resistance In Micro Organisms
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Author : G. E. W. Wolstenholme
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-16
Drug Resistance In Micro Organisms written by G. E. W. Wolstenholme and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-16 with Medical categories.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.