Overcoming Antimicrobial Resistance Of The Skin


Overcoming Antimicrobial Resistance Of The Skin
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Overcoming Antimicrobial Resistance Of The Skin


Overcoming Antimicrobial Resistance Of The Skin
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Author : Stephen K. Tyring
language : en
Publisher: Springer Nature
Release Date : 2021-05-07

Overcoming Antimicrobial Resistance Of The Skin written by Stephen K. Tyring and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-07 with Medical categories.


This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals. Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protozoan and helminth infections focusing primarily on initial and subsequent resistance to treatment. The book closes with a discussion on the potential solutions of innovative therapy including new delivery mechanisms, broad-spectrum antibiotics, phytocompounds, and biofilms. Chapters feature magnified, microscopic photos for identifying structures as they appear on the skin. Part of the Updates in Clinical Dermatology series, Overcoming Antimicrobial Resistance of the Skin is an important resource relevant during the COVID-19 pandemic, and is written for all medical healthcare professionals.



Technological Challenges In Antibiotic Discovery And Development


Technological Challenges In Antibiotic Discovery And Development
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2014-01-27

Technological Challenges In Antibiotic Discovery And Development written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-27 with Science categories.


Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.



The Resistance Phenomenon In Microbes And Infectious Disease Vectors


The Resistance Phenomenon In Microbes And Infectious Disease Vectors
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2003-03-26

The Resistance Phenomenon In Microbes And Infectious Disease Vectors written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Medical categories.


The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.



Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components


Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Mahendra Rai
language : en
Publisher: Academic Press
Release Date : 2013-05-24

Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Mahendra Rai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Science categories.


Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more



Drug Resistance In Bacteria Fungi Malaria And Cancer


Drug Resistance In Bacteria Fungi Malaria And Cancer
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Author : Gunjan Arora
language : en
Publisher: Springer
Release Date : 2017-03-21

Drug Resistance In Bacteria Fungi Malaria And Cancer written by Gunjan Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Medical categories.


This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.



Surveying Antimicrobial Resistance Approaches Issues And Challenges To Overcome


Surveying Antimicrobial Resistance Approaches Issues And Challenges To Overcome
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Author : Gilberto Igrejas
language : en
Publisher: Frontiers Media SA
Release Date : 2017-03-29

Surveying Antimicrobial Resistance Approaches Issues And Challenges To Overcome written by Gilberto Igrejas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-29 with Electronic book categories.


Why Antibiotic Resistance? The use of antibiotics in human and veterinary medicine may have consequences beyond their intended applications. The “One Health” concept recognizes that the health of humans is connected to the health of animals and the environment. Progress in molecular genetics is facilitating the rapid evaluation of the essentiality of these targets on a genomic scale. In 2015, a group of researchers established the International Conference on Antibiotic Resistance (IC2AR).The primary objective of this meeting is to bring together scientists involved in antibiotic resistance prevention and control. The IC2AR conducted its inaugural world congress in January 2015 at Caparica (Portugal). Antimicrobial resistance presents a significant challenge to scientists in the field of infectious diseases. The full knowledge of how antibiotics resistance is evolving and being transmitted between hosts in different ecosystems is taking on great importance. Necessary action includes research to define the scope of the problem including its various sources. This eBook comprises a series of original research and review articles dealing with the epidemiology of resistance in animal and zoonotic pathogens, mobile elements containing resistance genes, the omics of antimicrobial resistance, emerging antimicrobial resistance mechanisms, control of resistant infections, establishing antimicrobial use and resistance surveillance systems, and alternatives strategies to overcome the problem of antimicrobial resistance worldwide. Gilberto Igrejas, José Luis Capelo and Patrícia Poeta Scientific Committee of IC2AR, February 20th, 2017



Treating Infectious Diseases In A Microbial World


Treating Infectious Diseases In A Microbial World
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-01-03

Treating Infectious Diseases In A Microbial World written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-03 with Medical categories.


Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.



Biochemistry Of Drug Resistance


Biochemistry Of Drug Resistance
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Author : Sarfraz Ahmed
language : en
Publisher: Springer Nature
Release Date : 2021-08-05

Biochemistry Of Drug Resistance written by Sarfraz Ahmed and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-05 with Medical categories.


This book provides a comprehensive discussion on the current information and evidence on the latest developments in the field of drugs resistance. Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. This leads to negative outcomes at great risk of public health; therefore, increasing efforts are dedicated to the development of a new generation of medications that will help deal with this phenomenon. Decades of technological innovations in drug design have demonstrated the potential of resistance. Enormous information on various aspects of antibiotics resistance is available. However, literature on drug resistance specifically related to infectious and non-infectious diseases is rarely presented, particularly those focusing on the mechanisms, biochemistry, kinetics, dynamics, and management of drug resistance. Therefore, there is an immense need for a systematic compilation on the available information about this issue. All the chapters are logically selected and arranged to provide state-of-the-art information about all aspects of drugs resistance. After an introductory chapter, four chapters are dedicated to infectious microbial diseases, whereas two other chapters are complimenting this theme and focusing on drugs resistance in ear, nose and throat, and skin diseases. The recent advances in the understanding of drugs resistance in lung, neurological, kidney, heart, and liver diseases are also covered. Biochemistry of drugs resistance in cancer, HIV, ocular, reproductive, and diabetes diseases is also discussed. Finally, a chapter dedicated to the “management of drug resistance” has been included.



Antimicrobial Resistance


Antimicrobial Resistance
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Author : World Health Organization
language : en
Publisher:
Release Date : 2014

Antimicrobial Resistance written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.


Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.



Microbial Interactions At Nanobiotechnology Interfaces


Microbial Interactions At Nanobiotechnology Interfaces
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Author : R. Navanietha Krishnaraj
language : en
Publisher: John Wiley & Sons
Release Date : 2021-10-26

Microbial Interactions At Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-26 with Technology & Engineering categories.


MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.