Pharmaceutical Aspects Of Polymer Based Gene Delivery Systems Preparation Characterization And Stabilization
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Pharmaceutical Aspects Of Polymer Based Gene Delivery Systems Preparation Characterization And Stabilization
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Author : Jong-Yuh Cherng
language : en
Publisher:
Release Date : 1999
Pharmaceutical Aspects Of Polymer Based Gene Delivery Systems Preparation Characterization And Stabilization written by Jong-Yuh Cherng and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Polymers And Nanomaterials For Gene Therapy
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Author : Ravin Narain
language : en
Publisher: Woodhead Publishing
Release Date : 2016-01-09
Polymers And Nanomaterials For Gene Therapy written by Ravin Narain and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-09 with Science categories.
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications
Drug Delivery Systems Advanced Technologies Potentially Applicable In Personalised Treatment
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Author : Jorge Coelho
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-15
Drug Delivery Systems Advanced Technologies Potentially Applicable In Personalised Treatment written by Jorge Coelho and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-15 with Medical categories.
This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.
Drug Delivery Systems In Cancer Therapy
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Author : Dennis M. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-09-08
Drug Delivery Systems In Cancer Therapy written by Dennis M. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-08 with Medical categories.
Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
Polymeric Drug Delivery Systems
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Author : Glen S. Kwon
language : en
Publisher: CRC Press
Release Date : 2005-04-12
Polymeric Drug Delivery Systems written by Glen S. Kwon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-12 with Medical categories.
Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.
Seaweed Polysaccharides
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Author : Jayachandran Venkatesan
language : en
Publisher: Elsevier
Release Date : 2017-05-30
Seaweed Polysaccharides written by Jayachandran Venkatesan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-30 with Technology & Engineering categories.
Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides
Polymer Capsules
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Author : Ye Liu
language : en
Publisher: CRC Press
Release Date : 2019-05-10
Polymer Capsules written by Ye Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-10 with Science categories.
Polymers are one of the most versatile and important materials used for capsule preparation despite various others available. Suitably formulated capsules can securely protect ingredients, deliver them to targeted sites, and release them expeditiously, improving functions and minimizing adverse effects. New polymers are constantly being explored to develop more efficient capsules as they are routinely used in pharmaceuticals, consumer healthcare products, nutrients, and food. This book focuses on the current state of the art of polymer-based capsules and delivery systems. It describes the formulation processes of capsules developed from redox-responsive polymers and polymer-functionalized carbon nanotubes, in addition to shedding light on coacervation of polymers for encapsulation. It reviews different active ingredients that can be used with polymer capsules in various products, encapsulation of essential oils using such capsules, and development of polymer capsules of cells and bacteriophages.
Biopolymer Based Nanomaterials In Drug Delivery And Biomedical Applications
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Author : Hriday Bera
language : en
Publisher: Academic Press
Release Date : 2021-01-28
Biopolymer Based Nanomaterials In Drug Delivery And Biomedical Applications written by Hriday Bera and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-28 with Business & Economics categories.
Over the past few decades, there has been unprecedented progress in the design of versatile biopolymer-based nanoplatforms for pharmaceutical and biomedical applications, particularly due to their attractive traits, including excellent biocompatibility, outstanding biodegradability, low immunogenicity, and facile chemical modifiability. Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications serves as a clear and detailed body of information on the synthesis and characterization of biopolymer-based materials in nanomedicine. This book describes various nanomaterials consisting of biopolymers including polysaccharides (i.e., derived from plants, animals, bacteria, algae, and fungi) and polypeptides in terms of their structures, synthetic protocols, and characterization and uses as therapeutic drugs and gene delivery carriers and in other biomedical fields. The chapters of this book, which are contributed by internationally renowned scholars working in the arena of biopolymer-based nanomaterials, would offer a wide vision on the potential future applications of these nanomaterials in the delivery and targeting of bioactive molecules of pharmaceutical interests and in tissue engineering, biosensing, bioimaging, and diagnostic purposes. The state-of-the-art information presented in the book would also encourage young investigators and researchers to further bring cutting-edge developments in the field of nanomedicine in the near future. Provides a scholarly insight into the recent development of biopolymer-based nanomaterials Focuses on the diverse cutting-edge techniques for the fabrication of native and modified biopolymer-based nanoplatforms and their applications in drug delivery and biomedical fields Assesses the opportunities and challenges of biopolymer-based nanocarriers in pharmaceutical and biomedical research
Polymeric Gene Delivery Systems
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Author : Yiyun Cheng
language : en
Publisher: Springer
Release Date : 2018-09-04
Polymeric Gene Delivery Systems written by Yiyun Cheng and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-04 with Technology & Engineering categories.
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Recent Advances In Novel Drug Carrier Systems
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Author : Ali Demir Sezer
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-10-31
Recent Advances In Novel Drug Carrier Systems written by Ali Demir Sezer and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-31 with Medical categories.
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.