Pharmacogenomics A Primer For Clinicians
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Pharmacogenomics A Primer For Clinicians
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Author : Jerika T. Lam
language : en
Publisher: McGraw Hill Professional
Release Date : 2020-12-22
Pharmacogenomics A Primer For Clinicians written by Jerika T. Lam and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-22 with Medical categories.
An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.
Clinical Precision Medicine
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Author : Judy S. Crabtree
language : en
Publisher: Academic Press
Release Date : 2019-11-15
Clinical Precision Medicine written by Judy S. Crabtree and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-15 with Medical categories.
Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. - Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics - Features chapter contributions from leaders in the field - Consolidates fundamental concepts and current practices of precision medicine in one convenient resource
Pharmacogenomics
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Author : Showkat Ahmad Ganie
language : en
Publisher: Elsevier
Release Date : 2023-06-13
Pharmacogenomics written by Showkat Ahmad Ganie and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-13 with Medical categories.
Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book. - Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impacts - Describes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseases - Uses a consistent chapter structure to support understanding of the fundamental concepts in the area
Principles Of Pharmacogenetics And Pharmacogenomics
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Author : Russ B. Altman
language : en
Publisher: Cambridge University Press
Release Date : 2012-01-23
Principles Of Pharmacogenetics And Pharmacogenomics written by Russ B. Altman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-23 with Medical categories.
This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2012-10-12
Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-12 with Medical categories.
A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
Pharmacogenetics Kinetics And Dynamics For Personalized Medicine
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Author : David F. Kisor
language : en
Publisher: Jones & Bartlett Publishers
Release Date : 2013-02-19
Pharmacogenetics Kinetics And Dynamics For Personalized Medicine written by David F. Kisor and has been published by Jones & Bartlett Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-19 with Medical categories.
Pharmacogenetics, Kinetics, and Dynamics for Personalized Medicine provides a primer to understand pharmacogenetics (the study of genetic factors that influence how a drug works) in the applied context of pharmacokinetics (how the body handles a drug) and pharmacodynamics (the effects of a drug on the body). This valuable foundation illuminates how these principles and scientific advances can create optimal individual patient care, that is, "personalized medicine." Through specific drug examples, this resource explores how the genetic constitution of an individual may lead to the need for an altered dose or in some cases alternative drug therapy. Real-world cases highlight the specific relationships between genetics, drug action, and the body's response as well as adverse drug reactions, altered metabolism, and drug efficacy. Ethical issues concerning pharmacogenomics and study design are also discussed in this concise overview.
Pharmacogenomics In Clinical Therapeutics
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Author : Loralie J. Langman
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-09
Pharmacogenomics In Clinical Therapeutics written by Loralie J. Langman and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.
Advanced Assessment
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Author : Mary Jo Goolsby
language : en
Publisher: F.A. Davis
Release Date : 2022-11-07
Advanced Assessment written by Mary Jo Goolsby and has been published by F.A. Davis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-07 with Medical categories.
Your essential guide in the assessment and diagnostic process. Step by step, you’ll hone your ability to perform effective health assessments, obtain valid data, interpret the findings, and recognize the range of conditions that can be indicated by specific findings to reach an accurate differential diagnosis. You’ll have coverage of 170 conditions and symptoms across the lifespan at your fingertips. ***** Powerful little clinical assessment tool! “Book required for graduate nursing course. Didn't disappoint! Especially helpful with formulating the differential diagnoses in the care plan...”—Susan, Online Reviewer ***** Really good organization. Helpful descriptions. Easy to find information. “I actually really liked this text for my Advanced Assessment course. I liked how it was broken down by area or body system, and then further broken down my differential diagnosis. The information is organized in a way that makes sense and is super easy to skim to find exactly what you need.”—Alexx, Online Reviewer Expanded, Revised & Updated! Thoroughly updated to reflect the art and the science of primary care practice as well as the newest evidence and changes in health care New Chapter! Differential Studies New & Expanded! Content in Chapter 1 on history taking-techniques and skills for special populations Expanded! Lab diagnostics information, as well as discussions of health disparities, cultural humility, and competency New Content! Genetic testing for pharmacologic prescriptions for psychiatric mental health conditions New! Diagnosis algorithm decision trees designed to help nurses assess and diagnose conditions such as chronic sore throat, chronic insomnia, and more Coverage of 170 conditions and symptoms across the life span—including children, older adults, and pregnant patients. Complaint-focused approach organized by body system, including discussions of complex conditions Step-by-step how tos for taking a focused history, performing a physical based on presenting complaints/problems, and interpreting the findings Guidance on selecting diagnostic tests and interpreting those studies to help narrow down the diagnoses Prediction rules for selected disorders Quick-reference features, including red flags Ÿ assessment pearls Ÿ medications causing symptoms Ÿ and selected causes of symptoms
Psychiatric Genomics Recent Advances And Clinical Implications An Issue Of Psychiatric Clinics Of North America
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Author : James J. Crowley
language : en
Publisher: Elsevier Health Sciences
Release Date : 2025-05-20
Psychiatric Genomics Recent Advances And Clinical Implications An Issue Of Psychiatric Clinics Of North America written by James J. Crowley and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-20 with Medical categories.
In this issue of Psychiatric Clinics, guest editor Dr. James J. Crowley brings his considerable expertise to the topic of Psychiatric Genomics: Recent Advances and Clinical Implications. Top experts discuss recent advances and clinical implications of psychiatric genomics, providing a better understanding of what causes psychiatric disorders and how to use that knowledge to improve treatment for patients. Articles discuss a variety of disorders, such as OCD, autism, PTSD, and more. - Contains 17 relevant, practice-oriented topics including psychiatric pharmacogenomics; precision psychiatry; obsessive-compulsive disorder; anorexia nervosa; bipolar disorder; schizophrenia; suicidal behaviors; substance use disorders; and more - Provides in-depth clinical reviews on psychiatric genomics, offering actionable insights for clinical practice - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
The Asam Principles Of Addiction Medicine
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Author : Shannon C. Miller
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2024-02-15
The Asam Principles Of Addiction Medicine written by Shannon C. Miller and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-15 with Medical categories.
Principles of Addiction Medicine, 7th ed is a fully reimagined resource, integrating the latest advancements and research in addiction treatment. Prepared for physicians in internal medicine, psychiatry, and nearly every medical specialty, the 7th edition is the most comprehensive publication in addiction medicine. It offers detailed information to help physicians navigate addiction treatment for all patients, not just those seeking treatment for SUDs. Published by the American Society of Addiction Medicine and edited by Shannon C. Miller, MD, Richard N. Rosenthal, MD, Sharon Levy, MD, Andrew J. Saxon, MD, Jeanette M. Tetrault, MD, and Sarah E. Wakeman, MD, this edition is a testament to the collective experience and wisdom of 350 medical, research, and public health experts in the field. The exhaustive content, now in vibrant full color, bridges science and medicine and offers new insights and advancements for evidence-based treatment of SUDs. This foundational textbook for medical students, residents, and addiction medicine/addiction psychiatry fellows, medical libraires and institution, also serves as a comprehensive reference for everyday clinical practice and policymaking. Physicians, mental health practitioners, NP, PAs, or public officials who need reference material to recognize and treat substance use disorders will find this an invaluable addition to their professional libraries.