Pharmacogenomics An Introduction And Clinical Perspective
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Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2012-10-12
Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-12 with Medical categories.
A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
Pharmacogenomics An Introduction And Clinical Perspective
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Author : Joseph S. Bertino
language : en
Publisher: McGraw Hill Professional
Release Date : 2013
Pharmacogenomics An Introduction And Clinical Perspective written by Joseph S. Bertino and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Pharmacogenomics is comprehensive textbook detailing how genetic makeup affects a body's response to drugs.
Pharmacogenomics An Introduction And Clinical Perspective
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Author : Gavin Hodges
language : en
Publisher:
Release Date : 2019-01-11
Pharmacogenomics An Introduction And Clinical Perspective written by Gavin Hodges and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-11 with categories.
Pharmacogenomics
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Author : Joseph S. Bertino
language : en
Publisher:
Release Date : 2013
Pharmacogenomics written by Joseph S. Bertino and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Pharmacogenomics categories.
Principles Of Pharmacogenetics And Pharmacogenomics
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Author : Russ B. Altman
language : en
Publisher: Cambridge University Press
Release Date : 2012-01-23
Principles Of Pharmacogenetics And Pharmacogenomics written by Russ B. Altman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-23 with Medical categories.
This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
Handbook Of Pharmacogenomics And Stratified Medicine
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Author : Sandosh Padmanabhan
language : en
Publisher: Academic Press
Release Date : 2014-04-28
Handbook Of Pharmacogenomics And Stratified Medicine written by Sandosh Padmanabhan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-28 with Science categories.
Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details.Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. - Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise - Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics - Covers newer technologies– next generation sequencing, proteomics, metabolomics - Provides information on animal models, lymphoblastoid cell lines, stem cells - Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues - Includes chapters on the global implications of pharmacogenomics
Pharmacogenomics A Primer For Clinicians
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Author : Jerika T. Lam
language : en
Publisher: McGraw Hill Professional
Release Date : 2020-12-22
Pharmacogenomics A Primer For Clinicians written by Jerika T. Lam and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-22 with Medical categories.
An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.
Concepts In Pharmacogenomics
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Author : Martin M. Zdanowicz
language : en
Publisher: ASHP
Release Date : 2010
Concepts In Pharmacogenomics written by Martin M. Zdanowicz and has been published by ASHP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
The new science of pharmacogenomics aims to understand how an individual's genetic composition affects his/her response to a specific drug or class of drugs. By studying such characteristics as drug metabolizing enzymes, drug transporter activity, and receptor sensitivity, a pharmacist is better able to prescribe the right drug the first time.If you are pharmacist, resident, or student curious about this new field, start withConcepts in Pharmacogenomics. In this practical guide, you will find an overview of the science behind pharmacogenomics, followed by detailed chapters related to its clinical application and implementation.Features include: case studies in each chapter clinical pearls illustrations of key concepts figures, diagrams, and flow charts for visual learners key points summarized.
Preventive And Predictive Genetics Towards Personalised Medicine
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Author : Godfrey Grech
language : en
Publisher: Springer
Release Date : 2015-06-24
Preventive And Predictive Genetics Towards Personalised Medicine written by Godfrey Grech and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-24 with Science categories.
Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.