Principles Of Peptide Synthesis


Principles Of Peptide Synthesis
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Principles Of Peptide Synthesis


Principles Of Peptide Synthesis
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Author : M. Bodanszky
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Principles Of Peptide Synthesis written by M. Bodanszky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


A look at the shelves of a major library awakens doubts in the author of this small volume about the importance of writing a new introduction to peptide synthesis. This rather narrow area of bio-organic chemistry already has received considerable attention. A whole series of books deals with the synthesis of peptides. Some of these are textbooks written to support lecture courses on peptide synthesis. Others try to help the beginner, otherwise well versed in organic chemistry, to embark on some experimental project that requires the construction of peptide chains. Not less useful are the monographs which were compiled to aid the adept practitioner and to provide him with references to the growing literature of a very active field. Is there any need for a new book on peptide synthesis? Should we add a new volume to an already impressive and certainly useful series? The answer is not obvious. The author has already participated in two similar en deavors. The first edition! of "Peptide Synthesis", with M. A. Ondetti as coauthor, was meant to serve as an introduction for the beginner. It was rather well received by researchers who joined the field of peptide chemistry and were looking for initiation. While working on the 2 second edition with Drs. Klausner and Ondetti, we became painfully aware of the impossibility of the task.



Principles Of Peptide Synthesis


Principles Of Peptide Synthesis
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Author : Miklos Bodanszky
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 1984-12-31

Principles Of Peptide Synthesis written by Miklos Bodanszky and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-12-31 with Science categories.


No detailed description available for "Principles of Peptide Synthesis".



Principles Of Peptide Synthesis


Principles Of Peptide Synthesis
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Author : Miklos Bodanszky
language : en
Publisher: Springer
Release Date : 1993-09-15

Principles Of Peptide Synthesis written by Miklos Bodanszky and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-09-15 with Science categories.


Principles of Peptide Synthesis is a very successful book by one of the pioneers of contemporary bioorganic synthesis. Its first edition proved a valuable source that is kept close to the work bench for frequent consulting. Any researcher planning the formation of the peptide bond, be it for the synthesis of a peptide chain or a cyclic peptide, benefits from the author's experience. The concise and critical treatment of the steps involved: protection, activation and bond formation require careful planning to avoid racemization and undesired side reactions. The second edition has been completely revised and updated. New procedures that have been developed since the first edition was published and that did not fit into the original are added in a separate chapter. This separation of old and new make it possible to assess new ideas and discern novel trends.



The Practice Of Peptide Synthesis


The Practice Of Peptide Synthesis
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Author : Miklos Bodanszky
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

The Practice Of Peptide Synthesis written by Miklos Bodanszky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.


During the years 1980-81, as guests of the Deutsches Woll forschungsinstitut in Aachen, Germany, we were working on a small book entitled, "Principles of Peptide Synthesis". In the library of the Institute we noted that the volumes of Houben-Weyl's Handbuch der Organischen Chemie dealing with peptide synthesis were so much in use that they were ready to fall apart because the researchers of the Institute consulted them with amazing regularity. They were looking for references, but even more for experimental details which could be adapted to the particular problem they happened to face. In planning a new synthetic endeavor they tried to lean on the experience of others in analogous situations. This suggested to us that a smaller and hence more tractable book may be needed, a volume which can be kept on or near the bench to make examples of funda mental methods readily available in the laboratory. Such a collection could save numerous short trips to the library, a point particularly important where a library well equipped with the sources of the literature of peptide synthesis is not near at hand. Also, we thought that the envisaged book may be welcome by those who are more versed in English than in German. To our best knowledge no similar publi cation is available.



Synthetic Peptides


Synthetic Peptides
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Author : Gregory Grant
language : en
Publisher: Oxford University Press
Release Date : 2002-04-04

Synthetic Peptides written by Gregory Grant and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-04 with Science categories.


The first synthetic peptides were produced a century ago. In the ensuing period, they have developed as valuable research tools that are readily available to all researchers. However, since most researchers do not make their own peptides, they are often unfamiliar with not only the synthetic chemistry but also with important and useful aspects of design, analysis, handling, and applications. This volume is the second edition of a volume that was first published 10 years ago. It is written by experts in the field who provide detailed descriptions as well as practical advice for producing and using synthetic peptides. The various chapters cover peptide design considerations, the synthetic chemistry, the evaluation of the synthetic product, and the modern applications of synthetic peptides. This includes the basic principles of peptide structure, analysis and chain assembly as well as the latest in selective disulfide bond formation, new strategies for the production of large peptides, and sequencing peptides by mass spectrometry. This book was designed with the intent of providing useful information both for the novices to the field as well as more seasoned practitioners. Its contents will help prevent problems commonly encountered and allow scientists to optimize their use of synthetic peptides.



The Chemical Synthesis Of Peptides


The Chemical Synthesis Of Peptides
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Author : John Jones
language : en
Publisher: Oxford University Press, USA
Release Date : 1991

The Chemical Synthesis Of Peptides written by John Jones and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Language Arts & Disciplines categories.


This book focuses on the chemical principles behind the more important methods of peptide synthesis, and it provides a critical, concise, and up-to-date survey of the field.



An Introduction To Peptide Chemistry


An Introduction To Peptide Chemistry
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Author : P. D. Bailey
language : en
Publisher: John Wiley & Sons
Release Date : 1990

An Introduction To Peptide Chemistry written by P. D. Bailey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Science categories.


An Introduction to Peptide Chemistry P. D. Bailey, University of York Peptide chemistry is a key area in natural product chemistry, combining aspects of analysis, synthesis and biochemistry. In recent years peptide chemistry has emerged as a discipline in its own right, distinct from amino acid chemistry and protein chemistry. The importance of peptide chemistry is reflected in the intense research interest, exemplified by the progress made in solid-phase peptide synthesis. Recent developments in the determination and prediction of the three-dimensional structure of peptides, and in our understanding and control of their biosynthesis, have led to dramatic advances in the field. This book is intended as a short treatise on peptide chemistry aimed at upper-level undergraduates studying chemistry and biochemistry. This concise account has been thoughtfully presented; emphasis is placed on the principles of peptide chemistry, and how these relate to organic, physical, and biological chemistry. Salle + Sauerländer Aarau·Frankfurt am main·Salzburg



Peptide Synthesis And Applications


Peptide Synthesis And Applications
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Author : John Howl
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Peptide Synthesis And Applications written by John Howl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Science categories.


Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.



De Novo Peptide Design


De Novo Peptide Design
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Author : Vibin Ramakrishnan
language : en
Publisher: Academic Press
Release Date : 2022-09-17

De Novo Peptide Design written by Vibin Ramakrishnan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-17 with Science categories.


De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents. Gives comprehensive coverage, including peptide design, modeling, synthesis and applications Presents emerging topics in the design of peptide-based therapeutics Details the latest developments in the fields of therapeutic peptides and bio-nanotechnology Considers peptide design and the tailoring of peptides to specific functions Offers computational tools and algorithms for peptide design and experimental protocols for peptide chemistry



Amino Acid And Peptide Synthesis


Amino Acid And Peptide Synthesis
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Author : John Jones
language : en
Publisher: Oxford University Press, USA
Release Date : 1992

Amino Acid And Peptide Synthesis written by John Jones and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.


The principal methods for the synthesis of amino acids and peptides are outlined in this concise introduction. With its emphasis on chemical principles and strategies, the book should be of value to all undergraduate chemistry students.