Protein Homology Detection Through Alignment Of Markov Random Fields
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Protein Homology Detection Through Alignment Of Markov Random Fields
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Author : Jinbo Xu
language : en
Publisher: Springer
Release Date : 2015-01-22
Protein Homology Detection Through Alignment Of Markov Random Fields written by Jinbo Xu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-22 with Computers categories.
This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.
50 Years Of Statistical Physics In Mexico Development State Of The Art And Perspectives
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Author : Ramon Castañeda-Priego
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-13
50 Years Of Statistical Physics In Mexico Development State Of The Art And Perspectives written by Ramon Castañeda-Priego and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-13 with Science categories.
Research In Computational Molecular Biology
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Author : Roded Sharan
language : en
Publisher: Springer
Release Date : 2014-02-28
Research In Computational Molecular Biology written by Roded Sharan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-28 with Computers categories.
This book constitutes the refereed proceedings of the 18th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2014, held in Pittsburgh, PA, USA, in April 2014. The 35 extended abstracts were carefully reviewed and selected from 154 submissions. They report on original research in all areas of computational molecular biology and bioinformatics.
Homology Modeling
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Author : Sławomir Filipek
language : en
Publisher: Springer Nature
Release Date : 2023-03-23
Homology Modeling written by Sławomir Filipek and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-23 with Science categories.
This detailed volume provides state-of-the-art methodologies and reviews of important topics in the field of homology modeling. From homology modeling in the twilight zone and improving accuracy through sequence space analysis to approaches to construct multi-protein complex models, the book explores a wide variety of uses and applications of this valuable technique. Written for the highly successful Methods in Molecular Biology series, the chapters include introductions to their respective topics, lists of the necessary programs, webservers, and databases, step-by-step and readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Homology Modeling: Methods and Protocols serves as an ideal guide to recent homology modeling procedures, assumptions made, and model quality assessment that will illuminate the black box of homology modeling for novice readers and broaden the knowledge of this methodology for professionals.
Computational Phylogenetics
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Author : Tandy Warnow
language : en
Publisher: Cambridge University Press
Release Date : 2018
Computational Phylogenetics written by Tandy Warnow and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Computers categories.
This book presents the foundations of phylogeny estimation and technical material enabling researchers to develop improved computational methods.
Theoretical And Computational Methods In Genome Research
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Author : Sándor Suhai
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Theoretical And Computational Methods In Genome Research written by Sándor Suhai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The application ofcomputational methods to solve scientific and practical problems in genome research created a new interdisciplinary area that transcends boundaries tradi tionally separating genetics, biology, mathematics, physics, and computer science. Com puters have, of course, been intensively used in the field of life sciences for many years, even before genome research started, to store and analyze DNA or protein sequences; to explore and model the three-dimensional structure, the dynamics, and the function of biopolymers; to compute genetic linkage or evolutionary processes; and more. The rapid development of new molecular and genetic technologies, combined with ambitious goals to explore the structure and function ofgenomes ofhigher organisms, has generated, how ever, not only a huge and exponentially increasing body of data but also a new class of scientific questions. The nature and complexity of these questions will also require, be yond establishing a new kind ofalliance between experimental and theoretical disciplines, the development of new generations both in computer software and hardware technolo gies. New theoretical procedures, combined with powerful computational facilities, will substantially extend the horizon of problems that genome research can attack with suc cess. Many of us still feel that computational models rationalizing experimental findings in genome research fulfill their promises more slowly than desired. There is also an uncer tainty concerning the real position of a "theoretical genome research" in the network of established disciplines integrating their efforts in this field.
Introduction To Data Mining For The Life Sciences
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Author : Rob Sullivan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-07
Introduction To Data Mining For The Life Sciences written by Rob Sullivan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-07 with Science categories.
Data mining provides a set of new techniques to integrate, synthesize, and analyze tdata, uncovering the hidden patterns that exist within. Traditionally, techniques such as kernel learning methods, pattern recognition, and data mining, have been the domain of researchers in areas such as artificial intelligence, but leveraging these tools, techniques, and concepts against your data asset to identify problems early, understand interactions that exist and highlight previously unrealized relationships through the combination of these different disciplines can provide significant value for the investigator and her organization.
Research And Applications In Global Supercomputing
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Author : Segall, Richard S.
language : en
Publisher: IGI Global
Release Date : 2015-01-31
Research And Applications In Global Supercomputing written by Segall, Richard S. and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-31 with Computers categories.
Rapidly generating and processing large amounts of data, supercomputers are currently at the leading edge of computing technologies. Supercomputers are employed in many different fields, establishing them as an integral part of the computational sciences. Research and Applications in Global Supercomputing investigates current and emerging research in the field, as well as the application of this technology to a variety of areas. Highlighting a broad range of concepts, this publication is a comprehensive reference source for professionals, researchers, students, and practitioners interested in the various topics pertaining to supercomputing and how this technology can be applied to solve problems in a multitude of disciplines.
Machine Learning And Knowledge Discovery In Databases
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Author : Paolo Frasconi
language : en
Publisher: Springer
Release Date : 2016-09-03
Machine Learning And Knowledge Discovery In Databases written by Paolo Frasconi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-03 with Computers categories.
The three volume set LNAI 9851, LNAI 9852, and LNAI 9853 constitutes the refereed proceedings of the European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2016, held in Riva del Garda, Italy, in September 2016. The 123 full papers and 16 short papers presented were carefully reviewed and selected from a total of 460 submissions. The papers presented focus on practical and real-world studies of machine learning, knowledge discovery, data mining; innovative prototype implementations or mature systems that use machine learning techniques and knowledge discovery processes in a real setting; recent advances at the frontier of machine learning and data mining with other disciplines. Part I and Part II of the proceedings contain the full papers of the contributions presented in the scientific track and abstracts of the scientific plenary talks. Part III contains the full papers of the contributions presented in the industrial track, short papers describing demonstration, the nectar papers, and the abstracts of the industrial plenary talks.
Biotechnology Concepts Methodologies Tools And Applications
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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2019-06-07
Biotechnology Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-07 with Science categories.
Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.