Radicals In Biochemistry
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Free Radicals In Biology And Environment
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Author : F. Minisci
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Free Radicals In Biology And Environment written by F. Minisci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Our understanding of the quantitative aspects of free radical chemistry and the involvement of radicals in such areas as biology, medicine, the environment, etc., has developed spectacularly over recent years, yet the various topics are commonly discussed separately, in specific meetings and specialised publications. Free Radicals in Biology and Environment draws together two important areas of free radical chemistry, using as a bridge the fundamental physical chemistry of free radicals (spectroscopic detection of free radicals, evaluation of absolute rate constants, elucidation of mechanisms of free radical reactions and catalysis, photochemical and radiation processes, etc.). The most relevant topics covered are the EPR detection of radicals in biochemical systems and in pollutant formation and degradation, oxidation processes in biology and in the troposphere, radiation and induced damage, and atmospheric pollutants arising from incomplete combustion. Also covered are the chemistry and biochemistry of nitric oxide and peroxynitrite, the chemistry and biochemistry of DNA radicals, the role of radicals in myeloperoxidase, lignineperoxidase, radicals and cardiovascular injury, radiation and the fragmentation of cells and tissues.
Techniques In Free Radical Research
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Author : A.T. Diplock
language : en
Publisher: Elsevier
Release Date : 1991-12-11
Techniques In Free Radical Research written by A.T. Diplock and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-12-11 with Science categories.
Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage. Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.
Free Radicals In Chemistry Biology And Medicine
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Author : Toshikazu Yoshikawa
language : en
Publisher:
Release Date : 2000
Free Radicals In Chemistry Biology And Medicine written by Toshikazu Yoshikawa and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Antioxidants categories.
Radicals In Biochemistry
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Author : Kendall N. Houk
language : en
Publisher: Springer
Release Date : 2014-03-12
Radicals In Biochemistry written by Kendall N. Houk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-12 with Science categories.
With contributions by numerous experts
Free Radicals In Biology And Medicine
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Author : Barry Halliwell
language : en
Publisher: Oxford University Press, USA
Release Date : 1989
Free Radicals In Biology And Medicine written by Barry Halliwell and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Biochemistry categories.
"This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and their potential pitfalls), as well as the importance of antioxidants in the human diet." "This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and medical sciences."--BOOK JACKET.
Radicals In Biochemistry
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Author : D. E. Edmondson
language : en
Publisher: Springer Verlag
Release Date : 1983
Radicals In Biochemistry written by D. E. Edmondson and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
Free Radicals And Oxidation Phenomena In Biological Systems
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Author : Roberfroid
language : en
Publisher: CRC Press
Release Date : 1994-12-14
Free Radicals And Oxidation Phenomena In Biological Systems written by Roberfroid and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-12-14 with Medical categories.
This work offers an analysis of the biological processes mediated by free radicals, from a toxicological point of view, providing easy access to information in an integrated, coherent presentation. The chemistry and biochemistry of all principal types of radical are explained, and the multiple forms in whch radicals participate in living organisms are investigated.;This work should be of use to biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists and graduate students in these disciplines.
Oxygen Radicals In Biology And Medicine
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Author : Michael Simic
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Oxygen Radicals In Biology And Medicine written by Michael Simic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
Free Radical Damage And Its Control
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Author : C.A. Rice-Evans
language : en
Publisher: Elsevier
Release Date : 1994-02-09
Free Radical Damage And Its Control written by C.A. Rice-Evans and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-09 with Science categories.
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Free Radicals In Synthesis And Biology
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Author : F. Minisci
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Free Radicals In Synthesis And Biology written by F. Minisci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Free-radical reactions have been for long time the domain of the physical chemists and the basic chemical industry (polymerization of vinyl monomers, oxidation by molecular oxygen, chlorination of methane etc.), where the use of simple molecules and the possibility of partial conversions without heavy problems of product separations makes less dramatic the aspects of regio and chemoselectivity. As synonym of unselectivity, free radical reactions were considered of poor use in the synthesis of fine chemicals or sophisticated molecules, where a high selectivity is an essential condition for the success, or in the involvement of biological processes. Within the last 15 years, however, an authentic explosion of synthetic applications of free radical reactions occurred; they have gained a remarkable position among the selective methods of synthesis. At the same time the great importance of free radical reactions in fundamental biological processes and in the metabolism of drugs has been recognized. Thus a specialized meeting on these topics was generally felt appropriate. I had the honour and the onus to organize this workshop because for more than 30 years I have been involved in the research of free radical reactions. Thanks to a generous grant from NATO Scientific Affairs Division and the financial support of CNR and chemical industry (Montedison, Enichem, Zambon) such a meeting among almost 50 specialists and 15 observers of sufficient standard to take advantage of the discussion, became possible at Bardolino (Italy).