Recent Advances In Bioprocess Engineering And Bioreactor Design

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Recent Advances In Bioprocess Engineering And Bioreactor Design
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Author : Swasti Dhagat
language : en
Publisher: Springer Nature
Release Date : 2024-05-13
Recent Advances In Bioprocess Engineering And Bioreactor Design written by Swasti Dhagat and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-13 with Science categories.
This book provides insights into the recent developments in the field of bioprocess technology and bioreactor design. Bioprocess engineering or biochemical engineering is a subcomponent of chemical engineering, which encompasses designing and developing those processes and equipment that are required for the manufacturing of products from biological materials and sources, such as agriculture, pharmaceutical, chemicals, polymers, food, etc., or for the treatment of environmental process, for example, waste water. The main focus of this book is to highlight the advancements in the field of bioprocess technology and bioreactor design. The book is divided into various chapters briefing all aspects of bioprocess engineering and focusing on the advances in bioprocess engineering. The book summarizes introduction to bioprocess technology and microbiology, isolation and maintenance of microbial strains, and sterilization techniques for advanced-level students and researchers. Different models depicting kinetics of microbial growth, substrate consumption, and product formation are discussed. The applications of enzymes have increased tremendously and therefore understanding their metabolic pathways to increase yields is also briefly discussed. The calculations of mass and energy balances associated with entropy changes and free energy. This book also covers the approaches for handling different types of cell cultures and current advancements in the area of bioprocess strategies for different culture types, which scientists and researchers working in the different cell cultures can refer to. The downstream processing of various industrially important products is also a part of this book. Apart from that, the process economics which ensures the feasibility and quality of any biological process is also dealt with as the last section of the book.
Bioprocess Engineering
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Author : Shijie Liu
language : en
Publisher: Newnes
Release Date : 2012-11-07
Bioprocess Engineering written by Shijie Liu and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-07 with Science categories.
Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food, feed, pharmaceuticals, nutraceuticals, chemicals, and polymers and paper from biological materials. It also deals with studying various biotechnological processes. "Bioprocess Kinetics and Systems Engineering" first of its kind contains systematic and comprehensive content on bioprocess kinetics, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics-including batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering- introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, design and consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme of this book, while more advanced techniques and applications are covered with some depth. Many theoretical derivations and simplifications are used to demonstrate how empirical kinetic models are applicable to complicated bioprocess systems. Contains extensive illustrative drawings which make the understanding of the subject easy Contains worked examples of the various process parameters, their significance and their specific practical use Provides the theory of bioprocess kinetics from simple concepts to complex metabolic pathways Incorporates sustainability concepts into the various bioprocesses
Bioreactors
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Author : Carl-Fredrik Mandenius
language : en
Publisher: John Wiley & Sons
Release Date : 2016-02-16
Bioreactors written by Carl-Fredrik Mandenius and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Science categories.
In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.
Bioreactors
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Author : Goutam Saha
language : en
Publisher: CRC Press
Release Date : 2017-12-01
Bioreactors written by Goutam Saha and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Medical categories.
Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to within 15 L. However, it can easily be scaled up for large production in volume of cell mass in the drug and pharmaceutical industries. The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They discuss different control strategies as well as the thorough experimental research they conducted on this prototype bioreactor in which they applied a time delay control for yield maximization. To give you a complete understanding of the design and development of the see-saw bioreactor, the authors cover the mathematical model they use to describe the kinetics of fermentation, the genetic algorithms used for deriving the optimal time trajectories of the bioprocess variables, and the corresponding control inputs for maximizing the product yield. One chapter is devoted to the application of time delay control. Following a description of the bioreactor’s working setup in the laboratory, the authors sum up their investigation and define the future scope of work in terms of design, control, and software sensors.
Bioreaction Engineering Principles
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Author : Jens Nielsen
language : en
Publisher: Springer
Release Date : 2012-12-06
Bioreaction Engineering Principles written by Jens Nielsen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.
Bioreactor System Design
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Author : Juan A. Asenjo
language : en
Publisher: CRC Press
Release Date : 1994-11-17
Bioreactor System Design written by Juan A. Asenjo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-11-17 with Science categories.
Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as strain and media selection, that have an overwhelming influence on all further operations, is emphasized.;This work is intended for biochemical, chemical and bioprocess engineers; biotechnologists; industrial biochemists; micro- and molecular biologists; food scientists; and upper-level undergraduate and graduate students in these disciplines.
Advances In Bioprocess Engineering And Technology
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Author : Doraiswami Ramkrishna
language : en
Publisher: Springer
Release Date : 2021-10-01
Advances In Bioprocess Engineering And Technology written by Doraiswami Ramkrishna and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-01 with Technology & Engineering categories.
This book presents the select peer-reviewed proceedings of the International Conference on Advances in Bioprocess Engineering and Technology (ICABET 2020). The book covers all aspects of bioprocesses, especially related to fermentation technology, food technology, environmental biotechnology, and sustainable energy. Along with this primary theme, the focus is on recent advances in bioprocessing research such as biosensors, micro-reactors, novel separation techniques, bioprocess control, bio-safety, advanced techniques for waste to wealth generation, and nanobiotechnology. This contents are divided according to the major themes of the conference: (i) Fermentation Technology and Bioreactor, (ii) Food Pharmaceuticals and Health care, (iii) Environment and Agriculture, and (iv) Sustainable Energy. This book is intended to help students, researchers, and industry professionals acquire knowledge on innovative technologies and recent advancements in the field of bioprocess engineering and technology.
Algal Bioreactors
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Author : Eduardo Jacob-Lopes
language : en
Publisher: Elsevier
Release Date : 2024-11-21
Algal Bioreactors written by Eduardo Jacob-Lopes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Technology & Engineering categories.
Algal Bioreactors: Science, Engineering and Technology of Upstream Processes, Volume One, is part of a comprehensive two-volume set that provides all of the knowledge needed to design, develop, and operate algal bioreactors for the production of renewable resources. Supported by critical parameters and properties, mathematical models and calculations, methods, and practical real-world case studies, readers will find everything they need to know on the upstream and downstream processes of algal bioreactors for renewable resource production.Bringing together renowned experts in microalgal biotechnology, this book will help researchers, scientists, and engineers from academia and industry overcome barriers and advance the production of renewable resources and renewable energy from algae. Students will also find invaluable explanations of the fundamentals and key principles of algal bioreactors, making it an accessible read for students of engineering, microbiology, biochemistry, biotechnology, and environmental sciences. - Presents the physical, biological, environmental, and economic parameters of upstream processes in the operation and development of algal bioreactors to produce renewable resources - Explains the main configurations and designs of algal bioreactors, presenting recent innovations and future trends - Integrates the scientific, engineering, technology, environmental, and economic aspects of producing renewable resources and other valuable bioproducts using algal bioreactors - Provides real-world case studies at various scales to demonstrate the practical implementation of the various technologies and methods discussed
Current Developments In Biotechnology And Bioengineering
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Author : Ashok Pandey
language : en
Publisher: Elsevier
Release Date : 2022-08-18
Current Developments In Biotechnology And Bioengineering written by Ashok Pandey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-18 with Technology & Engineering categories.
Advances in Bioprocess Engineering, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a comprehensive overview of bioprocess systems, kinetics, bioreactor design, batch and continuous reactors and introduces key principles that enable bioprocess engineers to engage in analysis, optimization and design with consistent control over biological and chemical transformations. The bioprocessing sector is also updating its technologies with state-of-the art techniques to keep up with the rising demand of the industry and R&D. This book covers these aspects, taking readers through a step-by-step journey of bioprocessing while also guiding them towards a new era and future. - Covers state-of-the-art, technological advancements in the field of bioprocessing - Includes design and scale-up of bioreactors, monitoring and control systems, advances in upstream and downstream processing - Includes design and development of fermentation processes such as the suitability of experimental design, full factorial, central composite design, Box-Behnken, Plackett-Burman, and more
Bioprocess Engineering Principles
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Author : Pauline M. Doran
language : en
Publisher: Elsevier
Release Date : 1995-04-03
Bioprocess Engineering Principles written by Pauline M. Doran and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-03 with Science categories.
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.