Red Cell Development
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Red Cell Development
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Author :
language : en
Publisher: Elsevier
Release Date : 2008-09-12
Red Cell Development written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-12 with Science categories.
This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume. - The first comprehensive volume covering the breadth of the topic - The latest advancements that lead to novel directions in the study of red cells - An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body
Transcription Factors In Blood Cell Development
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Author : Tilman Borggrefe
language : en
Publisher: Springer Nature
Release Date : 2024-07-17
Transcription Factors In Blood Cell Development written by Tilman Borggrefe and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-17 with Science categories.
This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.
Transcriptional And Epigenetic Mechanisms Regulating Normal And Aberrant Blood Cell Development
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Author : Constanze Bonifer
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-12
Transcriptional And Epigenetic Mechanisms Regulating Normal And Aberrant Blood Cell Development written by Constanze Bonifer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-12 with Medical categories.
During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never cause a problem again. In this book we will therefore make a journey from asking how more primitive organisms use the epigenetic regulatory machinery to balance growth with differentiation control towards digging deep into what controls the function of specialized cells of the human immune system. We will first discover that flies make blood but exist without blood vessels, why fish make blood cells in the kidney and which precise genetic circuitries are required for these developmental pathways. We will then learn the regulatory principles that drive the differentiation of mature blood cells from stem cells and what controls their function in mammals. In the process, we will find out what unites hematopoietic stem cells and endothelial cells. Finally, we will shed light on the molecular mechanisms that either alter hematopoietic cell differentiation or lead to the development of cells with impaired function.
Stem Cells From Cord Blood In Utero Stem Cell Development And Transplantation Inclusive Gene Therapy
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Author : W. Holzgreve
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Stem Cells From Cord Blood In Utero Stem Cell Development And Transplantation Inclusive Gene Therapy written by W. Holzgreve and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
The title "Stem Cells from Cord Blood, In Utero Stem Cell Develop ment, and Transplantation-Inclusive Gene Therapy" suggests that more than one topic is combined in one workshop. Indeed, at first glance the recovery of stem cells from cord blood has to be seen as separate from the attempts to achieve effective in utero therapy by stem cell trans plantation, because the first issue deals with an innovative stem cell source as an alternative to bone marrow, which is already spreading rapidly in medical practice, whereas the second topic is still strictly ex perimental and only investigated in medical centers with the appropri ate background. It is, however, not only justified, but helpful to com bine the two topics in one workshop and consequently to cover them in the same volume of the Ernst Schering Research Foundation Work shop series, because they are intimately related and both based on the new insights into the biology of stem cells. Professor Werner Arber, the Nobel Laureate from the University of Basel, pointed out in his In- Professor Dr. W. Holzgreve VI Preface The participants of the workshop troductory Lecture that our understanding of hematopoietic stem cells as descendents of totipotent cells and our current approaches to using them in post-and prenatal therapy have been furthered significantly by genetic engineering technologies which are "artificial contributions to the process of biologic evolution".
Hematopoietic Stem Cell Development
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Author : Isabelle Godin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-27
Hematopoietic Stem Cell Development written by Isabelle Godin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-27 with Medical categories.
Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of –the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.
Explanatory Particularism In Scientific Practice
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Author : Melinda Bonnie Fagan
language : en
Publisher: Oxford University Press
Release Date : 2025-03-23
Explanatory Particularism In Scientific Practice written by Melinda Bonnie Fagan and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-23 with Science categories.
Explanatory Particularism in Scientific Practice offers a novel community-centric account of scientific explanation. On this view, explanations are products of collaborative activity in particular communities. Philosophers of science studying explanation have traditionally seen their task as analyzing the common or fundamental core of explanations across the sciences. Melinda Bonnie Fagan takes the opposite view: diversity of explanations across the sciences is a basic feature of scientific practice. A scientific community produces explanations that advance understanding of some target of interest, but just what features advance understanding, and what understanding amounts to in practice, varies widely over time and across scientific communities. This particularist approach brings new problems and questions to the fore, especially concerning interdisciplinarity: how (if at all) do explanation and understanding get beyond the boundary of a particular community? The particularist account also has implications bearing on the nature of understanding, the unity of science, objectivity, and science-society relations. The argument is elaborated using detailed case studies of explanatory model connection, or lack thereof: immunology and epidemiology models in the COVID-19 pandemic and the explanatory ambitions of systems biology, using the example of stem cell development. The argument concludes with an open-ended list of potential future case studies.
Physiology For Dental Students
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Author : D. B. Ferguson
language : en
Publisher: Butterworth-Heinemann
Release Date : 2014-04-24
Physiology For Dental Students written by D. B. Ferguson and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-24 with Science categories.
Physiology for Dental Students presents a combined view of physiological mechanisms and physiological systems. It discusses the oral importance of basic physiology. It addresses physiological principles and specific types of cells. Some of the topics covered in the book are the movements of materials across cell membranes; the fluid compartments of the body; the major storage of body water; histological and ultrastructural appearance of the salivary glands; the secretion of substances into the urine in the kidney; and the total osmotic activity of plasma. The morphology of the red blood cells is fully covered. The factors necessary for red blood cell development is discussed in detail. The text describes in depth the mechanical properties of smooth muscle. The process of breathing and the elasticity of lungs are presented completely. A chapter is devoted to the parts of the central nervous system. The book can provide useful information to dentists, doctors, students, and researchers.
Hematology In Practice
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Author : Betty Ciesla
language : en
Publisher: F.A. Davis
Release Date : 2018-11-27
Hematology In Practice written by Betty Ciesla and has been published by F.A. Davis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-27 with Medical categories.
Basic principles of hematology made memorable. Build a solid understanding of hematology in the context of practical laboratory practice and principles. Visual language, innovative case studies, role-playing troubleshooting cases, and laboratory protocols bring laboratory practice to life. Superbly organized, this reader-friendly text breaks a complex subject into easy-to-follow, manageable sections. Begin with the basic principles of hematology; discover red and white blood cell disorders; journey through hemostasis and disorders of coagulation; and then explore the procedures needed in the laboratory.
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1989
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Biomedical Index To Phs Supported Research
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Author :
language : en
Publisher:
Release Date : 1990
Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medicine categories.