Red Cell Rheology
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Red Cell Rheology
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Author : M. Bessis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Red Cell Rheology written by M. Bessis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Hemolysis during filtration through micropores studied by Chien et al. [I] showed a dependence on pressure gradient and pore diameter that, at the time of publication, did not permit an easy interpretation of the hemolytic mechanism. Acting on the assumption that thresholds of hemolysis are easier to correlate with physical forces than extents of hemolysis, we performed a series of experi ments repeating some of the conditions reported in [I] and then focusing on low L1P in order to define better the thresholds of hemolysis for several pore sizes. Employing a model of a deformed red cell shape at the pore entrance (based on micropipette observations) we related the force field in the fluid to a biaxial tension in the membrane. The threshold for lysis correlated with a membrane tension of 30 dynes/cm. This quantity is in agreement with lysis data from a number of other investigators employing a variety of mechanisms for introduc ing membrane tension. The sequence of events represented here is: a. Fluid forces and pressure gradients deform the cell into a new, elongated shape. b. Extent of deformation becomes limited by the resistance of the cell mem brane to undergo an increase in area. c. Fluid forces and pressure gradients acting on the deformed cell membrane cause an increase in biaxial tension in the membrane. d. When the strain caused by this tension causes pores to open in the membrane, the threshold for hemolysis has been reached [2].
Red Cell Rheology I
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Author : Stephen B. Shohet
language : en
Publisher:
Release Date : 1977
Red Cell Rheology I written by Stephen B. Shohet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Blood categories.
Red Blood Cell Aggregation
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Author : Oguz Baskurt
language : en
Publisher: CRC Press
Release Date : 2011-09-28
Red Blood Cell Aggregation written by Oguz Baskurt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-28 with Medical categories.
Red blood cells in humans-and most other mammals-have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this real
Red Cell Rheology I
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Author : Stephen B. Shohet
language : en
Publisher:
Release Date : 1977
Red Cell Rheology I written by Stephen B. Shohet and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Blood categories.
Blood Cells Rheology And Aging
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Author : Dieter Platt
language : en
Publisher: Springer
Release Date : 1988
Blood Cells Rheology And Aging written by Dieter Platt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
In the third Erlangen-Nuremberg symposium on experimental geronto logy we discussed the effect of aging on blood cells and rheology. Most studies with red cells have been performed on humans, rats, and rabbits. All these erythrocytes have no nucleus; the cells are therefore a model in which new synthesis of proteins is impossible. All the processes are age dependent except for exchange with the plasma. Investigations of red cells have attracted attention because of the latter's availability in large quantities from biochemists, physiologists, immunologists, and micro scopists. We now have a relative abundance of data on the biochemical and immunologic composition as well as on the ultrastructure of the cells. The second topic under discussion at the symposium was the immune system and cell receptors. One of the most apparent features of aging of the organism is progressive dysregulation of the immune system. As a result, the incidence of infection, cancer, and autoimmune and immune complex diseases increases. While we have a lot of new data on the function and differentiation of lymphoid cells, we have little informa tion on lymphocyte receptors during the aging process. Rheologic studies reflect changes in red cell deformability and blood coagulation. The erythrocyte deformability influences blood flow in all parts of the circulation. The fluidity of the red cell membranes controls whole blood viscosity. During aging, there are significant alterations in blood coagulation and hemostasis. One of the best known modifications of blood co agulation is a typical thrombophilic tendency with aging.
Clinical Aspects Of Blood Viscosity And Cell Deformability
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Author : G. D. O. Lowe
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Clinical Aspects Of Blood Viscosity And Cell Deformability written by G. D. O. Lowe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and the basic scientific and clinical observations, which have helped to open up understanding of this highly important aspect of human physiology and pathology in recent years. The text is logically divided into five sections beginning with blood cell deformability, then moving on to theoretical consideration of blood rheology, followed by accounts of the interrelationships between rheology, blood flow and vascular occlusion. The final two sections deal with blood rheology in clinical practice and therapeutic aspects of the study of blood flow. As regards blood cell deformability (Section A), the basic problem is set out by Kiesewetter and colleagues in the first paragraph of chapter 1 (p. 3), in which they point out that whereas human erythrocytes at rest have a diameter of approxi mately 7. 5 /-tm, nutritive capillaries have diameters ranging from 3-5 /-tm, and chapters in section A give an account of the ways in which the red cell can undergo deformation to permit capillary perfusion and the maintenance of the microcirculation.
White Blood Cells
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Author : U. Bagge
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
White Blood Cells written by U. Bagge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Proceedings, with Commentary, of the Symposium held at London, England October 3-4, 1981
Clinical Blood Rheology
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Author : Gordon D.O. Lowe
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Clinical Blood Rheology written by Gordon D.O. Lowe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.
Handbook Of Hemorheology And Hemodynamics
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Author : Oguz K. Baskurt
language : en
Publisher: IOS Press
Release Date : 2007
Handbook Of Hemorheology And Hemodynamics written by Oguz K. Baskurt and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Clinical Blood Rheology
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Author : Gordon D.O. Lowe
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Clinical Blood Rheology written by Gordon D.O. Lowe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.