Reducing Refining And Replacing The Use Of Animals In Toxicity Testing
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Reducing Refining And Replacing The Use Of Animals In Toxicity Testing
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Author : David G. Allen
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013
Reducing Refining And Replacing The Use Of Animals In Toxicity Testing written by David G. Allen and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
This thought-provoking book describes the ever-expanding "toolbox" of methods now available to reduce, refine, or replace animal usage in toxicity testing.
Reducing Refining And Replacing The Use Of Animals In Toxicity Testing
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Author : Dave Allen
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-10-31
Reducing Refining And Replacing The Use Of Animals In Toxicity Testing written by Dave Allen and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Science categories.
Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the environment at least as well as currently accepted methods. This book describes the ever-expanding "toolbox" of methods available to assess toxicity. Such techniques often result from our growing understanding of the biochemical and cellular pathways that mediate toxicity mechanisms. This permits evaluations of information generated from several sources to generate a "weight of evidence". By combining in silico, in vitro, and ex vivo methods with technologies that rely on biochemical- and cell-based in vitro assays, toxicologists are developing mechanistically based alternatives to live animal experimentation. This text also explores the complexities associated with adequate validation, and the assessment of test reliability and relevance. It provides an essential reference source for postgraduates, academics and industrialists working in this rapidly changing area.
Alternatives To Animal Testing
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Author : Hajime Kojima
language : en
Publisher: Springer
Release Date : 2018-12-27
Alternatives To Animal Testing written by Hajime Kojima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-27 with Medical categories.
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
The Principles Of Humane Experimental Technique
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Author : William Moy Stratton Russell
language : en
Publisher: Hyperion Books
Release Date : 1992
The Principles Of Humane Experimental Technique written by William Moy Stratton Russell and has been published by Hyperion Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Nature categories.
Science Medicine And Animals
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Author : Committee on the Use of Animals in Research (U.S.)
language : en
Publisher: National Academies Press
Release Date : 1991
Science Medicine And Animals written by Committee on the Use of Animals in Research (U.S.) and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
The necessity for animal use in biomedical research is a hotly debated topic in classrooms throughout the country. Frequently teachers and students do not have access to balanced,  factual material to foster an informed discussion on the topic. This colorful, 50-page booklet is designed to educate teenagers about the role of animal research in combating disease, past and present; the perspective of animal use within the whole spectrum of biomedical research; the regulations and oversight that govern animal research; and the continuing efforts to use animals more efficiently and humanely.
Use Of Laboratory Animals In Biomedical And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1988-02-01
Use Of Laboratory Animals In Biomedical And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-02-01 with Science categories.
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Oecd Series On Testing And Assessment Fish Toxicity Testing Framework
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2014-09-03
Oecd Series On Testing And Assessment Fish Toxicity Testing Framework written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-03 with categories.
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.
Anticoagulant Rodenticides And Wildlife
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Author : Nico W. van den Brink
language : en
Publisher: Springer
Release Date : 2017-11-09
Anticoagulant Rodenticides And Wildlife written by Nico W. van den Brink and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-09 with Science categories.
Commensal rodents pose health risks and cause substantial damage to property and food supplies. Rats have also invaded islands and pose a serious threat to native wildlife, particularly raptors and seabirds. Estimates of total damage from introduced rats range into the billions of dollars in developed countries. This book aims to provide a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment, along with practical guidance for characterization of hazards. This will be discussed in relation to their efficacy, and the societal needs for rodent control, and discussion of risk mitigation and development of alternatives. The flow in the book is planned as: a. introduction and setting the scene b. problem description (risks and effects on non-targets and secondary poisoning, development of resistance) c. ; alternatives, regulation and risk mitigation d. conclusions and recommendations
Information Resources In Toxicology Volume 1 Background Resources And Tools
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-05-16
Information Resources In Toxicology Volume 1 Background Resources And Tools written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-16 with Technology & Engineering categories.
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field
Elgar Concise Encyclopedia Of Animal Law
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Author : Joan E. Schaffner
language : en
Publisher: Edward Elgar Publishing
Release Date : 2025-07-15
Elgar Concise Encyclopedia Of Animal Law written by Joan E. Schaffner and has been published by Edward Elgar Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-15 with Law categories.
With contributions from over 135 international experts, this Encyclopedia provides an expansive overview of the emerging field of animal law. Focusing on the legal regulation of human interactions with non-human animals, the volume serves as an insightful guide to how the law can promote the wellbeing of animals as well as the environment.