Reviews On Biomarker Studies In Psychiatric And Neurodegenerative Disorders
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Reviews On Biomarker Studies In Psychiatric And Neurodegenerative Disorders
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Author : Paul C. Guest
language : en
Publisher: Springer
Release Date : 2019-02-12
Reviews On Biomarker Studies In Psychiatric And Neurodegenerative Disorders written by Paul C. Guest and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-12 with Science categories.
This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.
Biomarkers Of Neurological And Psychiatric Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-10-29
Biomarkers Of Neurological And Psychiatric Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-29 with Medical categories.
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Studies On Psychiatric Disorders
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Author : Anna Dietrich-Muszalska
language : en
Publisher: Springer
Release Date : 2015-01-02
Studies On Psychiatric Disorders written by Anna Dietrich-Muszalska and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-02 with Science categories.
This authoritative volume reviews clinical, pathophysiological and therapeutic aspects of oxidative and nitrosative stress in different psychiatric disorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeutic aspects. Together, these chapters present the environmental, genetic and neurodevelopmental factors in the generation of oxidative stress in psychiatric disorders, with particular emphasis on the biochemical changes associated with oxidative stress in dopaminergic and glutamate neurotransmission as well as mitochondrial dysfunction in the brain and peripheral cells. Through an investigation of glutamic acid decarboxylase (GAD) abnormalities in schizophrenia, the book provides a coherent framework to account for the impact of oxidative stress on pathological phenomena ranging from cellular to cognitive and clinical aspects. It describes biomarkers of oxidative damage, the role of oxidative stress in numerous abnormalities of biochemical pathways in the pathophysiology of schizophrenia, the development of new investigative techniques, specially neuroimaging, and studies of apoptotic pathways that seem to prove neurodegenerative and neurodevelopmental theories. Written by leading researchers in their fields, Studies on Psychiatric Disorders explores therapeutic approaches with aspects of various antioxidants, cryostimulation, and hyperbaric oxygen treatment in oxidative stress in neuropsychiatric diseases. The volume also discusses the role of antipsychotics in the treatment of schizophrenia on nitric oxide generation and biomarkers of oxidative stress together with the clinical symptomatology. Overall, it proposes that novel therapeutic strategies such as supplementation with antioxidants—in particular polyphenols, ω-3 fatty acids or combination of both—could be effective for long-term treatment of some neuropsychiatric disorders.
Biomarkers Of Brain Injury And Neurological Disorders
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Author : Kevin K. W. Wang
language : en
Publisher: CRC Press
Release Date : 2014-10-28
Biomarkers Of Brain Injury And Neurological Disorders written by Kevin K. W. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer’s disease.
Pathophysiologic Insights From Biomarker Studies In Neurological Disorders
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Author : Tobias Ruck
language : en
Publisher: Frontiers Media SA
Release Date : 2020-04-01
Pathophysiologic Insights From Biomarker Studies In Neurological Disorders written by Tobias Ruck and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with categories.
Neurodegenerative Diseases Biomarkers
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Author : Philip V. Peplow
language : en
Publisher: Humana
Release Date : 2021-10-21
Neurodegenerative Diseases Biomarkers written by Philip V. Peplow and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Medical categories.
This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.
Late Onset Schizophrenia
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Author : Robert Howard
language : en
Publisher: Routledge
Release Date : 1999
Late Onset Schizophrenia written by Robert Howard and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Aging categories.
Schizophrenia, which starts in middle age or late life, has been described as 'the darkest area of psychiatry.' It is certainly controversial, with much disagreement about cut-off ages, diagnostic criteria and nomenclature. The contributors to this unique and very important book represent views from Europe and North America as well as Australia, Japan, and Nepal; they come from backgrounds of clinical practice and research. The contributors and editors were motivated by common aims: to review current international knowledge about late onset schizophrenia, to debate issues of heterogenity, gender, brain maturation and aging, putative structural and functional cerebral substrates for psychosis, to reach consensus on diagnosis and terminology, and to future research directions. The resulting book is an unqualified success which as well as being invaluable in old age psychiatry, sheds light on all aspects of schizophrenia treatment and research.
Alzheimer S Disease Drug Development
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Author : Jeffrey Cummings
language : en
Publisher: Cambridge University Press
Release Date : 2022-03-31
Alzheimer S Disease Drug Development written by Jeffrey Cummings and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Business & Economics categories.
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Reviews On Biomarker Studies In Aging And Anti Aging Research
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Author : Paul C. Guest
language : en
Publisher: Springer Nature
Release Date : 2019-09-06
Reviews On Biomarker Studies In Aging And Anti Aging Research written by Paul C. Guest and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-06 with Science categories.
Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas.
Neuropsychiatric Disorders And Epigenetics
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Author : Jacob Peedicayil
language : en
Publisher: Elsevier
Release Date : 2023-09-29
Neuropsychiatric Disorders And Epigenetics written by Jacob Peedicayil and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Science categories.
Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy. By helping to define epigenetics as a key player in neuropsychiatric disorders, this volume empowers new research, clinical translation, and pharmacological advances, and highlights promising directions for ongoing investigation. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Features extensive use of diagrams, illustrations, tables, and graphical abstracts for each section to reinforce understanding Includes chapter contributions from leading global experts