Rna Design

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Rna Design

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Author : Alexander Churkin
language : en
Publisher: Springer Nature
Release Date : 2024-09-23

Rna Design written by Alexander Churkin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-23 with Science categories.

This volume provides comprehensive methods on RNA design. Chapters details traditional RNA design in secondary structure, RNA design in tertiary structure, and RNA design applications and assessments. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Design: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Rna Folding

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Author : Ronny Lorenz
language : en
Publisher: Springer Nature
Release Date : 2024-05-23

Rna Folding written by Ronny Lorenz and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-23 with Science categories.

To understand and predict the behavior and function of RNAs, sophisticated tools are required to simulate and analyze their potential for forming structures. This volume discusses the various levels of prediction and algorithmic approaches to RNA folding. The chapters in this book cover topics such as energy parameters of the nearest-neighbor (NN) energy model; classified dynamic programming to address exponential growth of candidate structures that an RNA molecule may fold into; sequence evolution and conserved structures among multiple RNA sequences; the latest framework capable of handling both positive and negative RNA sequence design objectives; and kinetic folding approaches that look at the dynamic nature of RNA folding. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, RNA Folding: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this important and developing field.

Rna Structure Prediction

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Author : Risa Karakida Kawaguchi
language : en
Publisher: Springer Nature
Release Date : 2023-01-27

Rna Structure Prediction written by Risa Karakida Kawaguchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-27 with Science categories.

This book explores recent progress in RNA secondary, tertiary structure prediction, and its application from an expansive point of view. Because of advancements in experimental protocols and devices, the integration of new types of data as well as new analysis techniques is necessary, and this volume discusses additional topics that are closely related to RNA structure prediction, such as the detection of structure-disrupting mutations, high-throughput structure analysis, and 3D structure design. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to quality research results. Authoritative and practical, RNA Structure Prediction serves as a valuable guide for both experimental and computational RNA researchers.

Rna Interference

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Author : David R. Engelke
language : en
Publisher: Elsevier
Release Date : 2005-02-28

Rna Interference written by David R. Engelke and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-28 with Science categories.

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.RNA Interference will cover RNAi in non-vertebrates (plants, C. elegans, drosophila, and S. pombe), and Mammalian systems (human and non-human cells). This volume discusses extensive methodology related to delivery methods high throughput strategies and prospects as a human therapy agent.* One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences

Riboswitches As Targets And Tools

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Author :
language : en
Publisher: Academic Press
Release Date : 2015-01-12

Riboswitches As Targets And Tools written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-12 with Science categories.

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in riboswitches as targets and tools and contains sections on such topics as constructing and optimizing artificial riboswitches, live cell imaging and intracellular sensors with artificial riboswitches, conditional control of gene expression with artificial riboswitches, using artificial riboswitches for protein evolution and pathway optimization, and anti-riboswitch drug screens. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in riboswitches as targets and tools - Contains sections on such topics as constructing and optimizing artificial riboswitches, synthetic biology: live cell imaging and intracellular sensors with artificial riboswitches, synthetic biology: conditional control of gene expression with artificial riboswitches, synthetic biology: using artificial riboswitches for protein evolution and pathway optimization, anti-riboswitches drug screens

Rna Nanotechnology And Therapeutics

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Author : Peixuan Guo
language : en
Publisher: CRC Press
Release Date : 2022-07-18

Rna Nanotechnology And Therapeutics written by Peixuan Guo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-18 with Medical categories.

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, immunorecognition of RNA nanomaterials, RNA chemistry for nanoparticle synthesis, and conjugation and labeling. Presents the latest research and discoveries in RNA nanotechnology Features contributions from world-class experts in the field Covers RNA nanoparticles in therapeutics Describes self-assembled RNA nanoparticles

Biophysics Of Rna Folding

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Author : Rick Russell
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-09

Biophysics Of Rna Folding written by Rick Russell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-09 with Science categories.

This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns. In addition to the fundamental features of RNA folding, the central experimental and computational approaches in the field are presented with an emphasis on their individual strengths and limitations, and how they can be combined to be more powerful than any method alone; these approaches include NMR, single molecule fluorescence, site-directed spin labeling, structure mapping, comparative sequence analysis, graph theory, course-grained 3D modeling, and more. This volume will be of interest to professional researchers and advanced students entering the field of RNA folding.

Rna Origami

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Author : Fouad Sabry
language : en
Publisher: One Billion Knowledgeable
Release Date : 2025-03-06

Rna Origami written by Fouad Sabry and has been published by One Billion Knowledgeable this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-06 with Science categories.

Unlock the revolutionary potential of RNA origami in the rapidly evolving field of DNA nanotechnology. This book provides a comprehensive yet accessible exploration of how RNA structures can be rationally designed for applications in molecular engineering, nanomedicine, and synthetic biology. Whether you're a researcher, student, or enthusiast, this book offers critical insights into the next frontier of biomolecular design. Chapters Brief Overview: 1: RNA origami – Introduces the concept of RNA origami and its significance in nanotechnology. 2: Native state – Examines RNA folding and stability in its natural biological environment. 3: Biomolecular structure – Discusses fundamental principles governing the architecture of biomolecules. 4: Holliday junction – Explores this key nucleic acid structure and its role in genetic recombination. 5: Nucleic acid quaternary structure – Covers higherorder structural organization in nucleic acids. 6: Spherical nucleic acid – Details how nucleic acids form spherical nanostructures with novel applications. 7: Protein biosynthesis – Explains RNA’s role in guiding the synthesis of proteins. 8: Biomolecule – Provides insights into the structure and function of biomolecules in nanotechnology. 9: Nanoruler – Introduces nanorulers and their application in precise molecular measurements. 10: Nucleic acid tertiary structure – Analyzes the intricate folding patterns of nucleic acids. 11: TectoRNA – Highlights modular RNA units used for constructing complex nanostructures. 12: Nucleic acid design – Discusses principles and strategies for designing functional RNA and DNA. 13: Molecular models of DNA – Explores computational and physical models of DNA structures. 14: Nucleic acid structure – Examines structural variations in DNA and RNA molecules. 15: DNA – Provides a foundational understanding of DNA’s role in biological and synthetic systems. 16: Nucleic acid secondary structure – Explores base pairing and folding patterns critical for RNA function. 17: Base pair – Discusses fundamental basepairing rules and their influence on nucleic acid stability. 18: History of RNA biology – Chronicles key discoveries shaping modern RNA research. 19: DNA nanotechnology – Explains how DNA is engineered for nanoscale applications. 20: DNA origami – Introduces the concept of folding DNA into precise nanoscale shapes. 21: Noncanonical base pairing – Explores alternative basepairing interactions in RNA and DNA structures. With a clear structure and indepth exploration, this book equips professionals, students, and hobbyists with the knowledge to navigate the exciting intersection of RNA origami and DNA nanotechnology. By bridging molecular biology and engineering, this resource ensures readers stay ahead in an era where synthetic biology is reshaping science and technology.

Automata Languages And Programming

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Author : Jos C.M. Baeten
language : en
Publisher: Springer
Release Date : 2003-01-01

Automata Languages And Programming written by Jos C.M. Baeten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-01 with Computers categories.

The refereed proceedings of the 30th International Colloquium on Automata, Languages and Programming, ICALP 2003, held in Eindhoven, The Netherlands in June/July 2003. The 84 revised full papers presented together with six invited papers were carefully reviewed and selected from 212 submissions. The papers are organized in topical sections on algorithms, process algebra, approximation algorithms, languages and programming, complexity, data structures, graph algorithms, automata, optimization and games, graphs and bisimulation, online problems, verification, the Internet, temporal logic and model checking, graph problems, logic and lambda-calculus, data structures and algorithms, types and categories, probabilistic systems, sampling and randomness, scheduling, and geometric problems.

Spherical Nucleic Acids

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Author : Chad A. Mirkin
language : en
Publisher: CRC Press
Release Date : 2021-10-14

Spherical Nucleic Acids written by Chad A. Mirkin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-14 with Science categories.

Spherical nucleic acids (SNAs) comprise a nanoparticle core, and a densely packed and highly oriented nucleic acid shell. They have novel structure-dependent properties that differ from those of linear nucleic acids and that makes them useful in chemistry, biology, the life sciences, medicine, materials science, and engineering. This book is a reprint volume that compiles 101 key papers that have been published by the Mirkin Group at Northwestern University, USA, and their collaborators over the past more than two decades. Volume 1 provides an overview and a historical framework of SNAs and discusses their enabling features, which set them apart from all other forms of matter. Volume 2 covers the general design rules for colloidal crystal engineering with DNA, spanning the building blocks and DNA- and RNA-based "programmable bonds" that can be utilized in preparing such structures. Volume 3 continues the discussion of colloidal crystallization processes and routes to hierarchical assembly, featuring dynamic nanoparticle superlattices and lattices prepared on surfaces or via templating strategies, and explores what one can uniquely learn from and do with colloidal crystals prepared from nucleic acid–functionalized nanomaterials in optics, plasmonics, and catalysis. Volume 4 covers the role of SNAs in biomedicine, especially as diagnostic probes both inside and outside of cells, and treatments based on gene regulation and immunotherapy.