Rna Dna And Cancer
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Rna Dna And Cancer
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Author : Joseph G. Sinkovics
language : en
Publisher: Springer
Release Date : 2016-04-01
Rna Dna And Cancer written by Joseph G. Sinkovics and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-01 with Medical categories.
In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges. The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe. This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells.
Rna And Cancer
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Author : Jane Y. Wu
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-12
Rna And Cancer written by Jane Y. Wu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Medical categories.
Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer examines the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment. A particular focus is mRNA splicing, but other topics such as microRNAs, mRNA stability, the perinucleolar compartment, and oligonucleotide therapeutics are also covered in detail. All chapters have been written by internationally renowned experts. The book is intended for all with an interest in gene regulation and cancer biology, and especially for those not directly working on RNA biology, including clinicians and medical students. It is hoped that it will stimulate further innovative research collaborations between RNA biologists and cancer researchers to the benefit of patients.
Dna And Rna Cleavers And Chemotherapy Of Cancer And Viral Diseases
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Author : B. Meunier
language : en
Publisher: Springer
Release Date : 1996-03-31
Dna And Rna Cleavers And Chemotherapy Of Cancer And Viral Diseases written by B. Meunier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-31 with Science categories.
The past decade has witnessed a burst of activity and interest in the discovery and design of drugs that cleave DNA and RNA with sequence specificity. This interest stems from the potential of this class of compounds to be useful as therapeutics agents, in particular in the field of the treatment of cancer and viral diseases. Further, a side benefit of such studies is the discovery of novel mechanisms and uses of such agents as tools in the study of structure and function of nucleic acids. Up to now, no international meeting has been organized to recognize the immense progress that has been made in this field. The field of DNA and RNA cleavage by natural and chemical drugs now includes researchers working with rather dissimilar agents but with common underlying mechanisms of DNA damage. Until recently, these scientists were working in separate, apparently unrelated areas, such as the enediyne antibiotics and their synthetic analogues, bleomycin-metal complexes, metal-drug complexes, ribozymes and ribozyme mimics, and antisense and antigene oligonucleotides, etc. It is now clear that these research areas have in common strategies and targets. Researchers representing these areas worked together at this workshop where these common interests were discussed and scientific ideas modified and criticized. Such a workshop should lead to new research approaches and collaborative interactions, and is expected to significantly enhance the progress in the field of DNA and RNA cleavage.
The Molecular Biology Of Cancer
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Author : Harris Busch
language : en
Publisher: Academic Press
Release Date : 2013-10-22
The Molecular Biology Of Cancer written by Harris Busch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
The Molecular Biology of Cancer discusses the state of progress in the molecular biology of cancer. The book describes the effects of anticancer agents on nucleolar ultrastructure; the role of chromosomes in the causation and progression of cancer and leukemia; the replication, modification, and repair of DNA. The text also describes the metabolism and utilization of messenger RNA and other high molecular weight RNA and low molecular weight nuclear RNA; the characteristics, structures, and functions of nuclear proteins; and the process of protein synthesis. Nucleotides are reviewed with regard to its biosynthesis, inhibition of synthesis, and development of resistance to inhibitors. The book further tackles the biochemical mechanisms of chemical carcinogenesis; the oncogenic viruses; and the molecular correlation concept. The text also demonstrates phenotypic variability as a manifestation of translational control; and plasmacytomas. Molecular biologists, virologists, pathologists, cell biologists, oncologists, pharmacologists, and students taking related courses will find the book useful.
Role Of Rna In Molecular Diagnostics Of Cancer
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Author : Cesar Wong
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-01
Role Of Rna In Molecular Diagnostics Of Cancer written by Cesar Wong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-01 with categories.
Dna Double Helix The Chemistry Of Cancer
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Author : Ramaswamy H. Sarma
language : en
Publisher: Adenine Press, Incorporated
Release Date : 1988
Dna Double Helix The Chemistry Of Cancer written by Ramaswamy H. Sarma and has been published by Adenine Press, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Cancer categories.
Cancer Rnome Nature Evolution
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Author : Mansi Arora
language : en
Publisher: Springer
Release Date : 2018-11-02
Cancer Rnome Nature Evolution written by Mansi Arora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Medical categories.
In the last decade, researchers working in the field of cancer biology have shifted their focus from genetic defects to epigenetic dysregulation, especially that of non-coding RNAs (ncRNAs). This book encompasses a comprehensive review of the transcriptional landscape of the cell and its involvement in the cancer pathophysiology. The first two chapters elucidate the basics of biosynthesis, mechanism of action and modulation of the epigenetic regulation of gene expression by coding as well as non-coding RNAs. The third chapter discusses the aberrant expression of the cellular RNome in the cancer cells and highlights its role in the orchestration of processes involved in evolution as well as the sustenance of cancer cells. The fourth chapter describes the recent advances in the field of translating the transcriptome into diagnostic/prognostic biomarkers and as targets for novel anti-cancer therapies. The final chapter then reviews the emerging experimental approaches to screen, identify and explore the functions of ncRNAs. Providing valuable insights into the field of RNome in the context of cancer, this book is helpful to students, researchers and clinicians..
Dna Tumor Viruses
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Author : Blossom Damania
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-19
Dna Tumor Viruses written by Blossom Damania and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-19 with Medical categories.
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Methylation
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Author : Anica Dricu
language : en
Publisher: Inst za onkologiju i radiol
Release Date : 2012-11-28
Methylation written by Anica Dricu and has been published by Inst za onkologiju i radiol this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-28 with Medical categories.
Alterations in the normal DNA methylation processes are known to have major consequences for embryonic development and are associated with congenital defects, autoimmunity, aging and malignant transformation. The main purpose of this book is to provide information about the importance of methylation mechanisms in human health and disease. The book, covers the basic mechanism of DNA and protein methylation, aiming at the advanced undergraduate and graduate biomedical students and researchers working in the epigenetic area. The textbook chapters provide background as well as advanced information in the methylation area. On the other hand, it provide readers with both classical and relevant recent discoveries that have been made in the field, pointing out pathways where questions remain.
New Advances In Rna Targeting
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Author : Olga N. Ilinskaya
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04
New Advances In Rna Targeting written by Olga N. Ilinskaya and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with RNA targeting categories.