Role Of Metabolism In Regulating Immune Cell Fate Decisions
DOWNLOAD
Download Role Of Metabolism In Regulating Immune Cell Fate Decisions PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Role Of Metabolism In Regulating Immune Cell Fate Decisions book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Role Of Metabolism In Regulating Immune Cell Fate Decisions
DOWNLOAD
Author : Anna Ohradanova-Repic
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-26
Role Of Metabolism In Regulating Immune Cell Fate Decisions written by Anna Ohradanova-Repic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-26 with categories.
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Immune Metabolism In Health And Tumor
DOWNLOAD
Author : Bin Li
language : en
Publisher: Springer
Release Date : 2017-09-05
Immune Metabolism In Health And Tumor written by Bin Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Medical categories.
This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients. The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of these pathways can lead to immune disorders. In different contexts, such as a tumor microenvironment, immune-cell function and identity may be modified not only by cytokines and checkpoint molecules, but also by nutrient availability and other metabolic stimuli. Transcriptional reprogramming confers many of the changes in immune cell metabolism that are seen when a T-cell, for example, undergoes activation or functional adaptation to different environments. Lastly, immune cells can destructively or protectively participate in human metabolic homeostasis or disorders. This book summarizes immune-metabolism from a variety of different perspectives, including the ways in which metabolic cues, pathways, and requirements of immune cells change in conditions of homeostasis and activation. The exploration of the significance of metabolic checkpoints and other cues, particularly in the context of cancer and immune disorders, may form the foundation for the development of therapeutics.
The Heterogeneity Of Cancer Metabolism
DOWNLOAD
Author : Anne Le
language : en
Publisher: Springer
Release Date : 2018-06-26
The Heterogeneity Of Cancer Metabolism written by Anne Le and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-26 with Medical categories.
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Crossroads Between Innate And Adaptive Immunity
DOWNLOAD
Author : Peter D. Katsikis
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-08
Crossroads Between Innate And Adaptive Immunity written by Peter D. Katsikis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-08 with Medical categories.
This compilation presents mini-reviews derived from work presented at the Aegean Conference: "First Crossroads between Innate and Adaptive Immunity," which occurred in October, 2005 at the Hilton Conference Center on the island of Rhodes, Greece. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune networks, antigen presentation, and adaptive immune responses, each headlined by a leading scientist.
Protein Kinase Mediated Decisions Between Life And Death
DOWNLOAD
Author : Ayse Basak Engin
language : en
Publisher: Springer Nature
Release Date : 2021-02-04
Protein Kinase Mediated Decisions Between Life And Death written by Ayse Basak Engin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-04 with Medical categories.
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
A Year In Review Discussions In Immunological Memory
DOWNLOAD
Author : Scott N. Mueller
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-30
A Year In Review Discussions In Immunological Memory written by Scott N. Mueller and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-30 with Medical categories.
Insights In Microorganisms In Vertebrate Digestive Systems 2022
DOWNLOAD
Author : Weiqi He
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-19
Insights In Microorganisms In Vertebrate Digestive Systems 2022 written by Weiqi He and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-19 with Science categories.
This Research Topic is part of the Insights in Frontiers in Microbiology series. We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists in the field of Microbiology have been exceptional, leading to major advancements. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This specific editorial initiative, led by Dr. Weiqi He, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances and future perspectives in the field. The Research Topic solicits brief, forward-looking contributions from associate editors and review editors that describe the state of the art, outlining recent developments and major achieved accomplishments, future challenges and how to address those challenges to move the field forward. Reviews, Mini-Reviews, Perspectives, and Opinions summarizing the current state and future directions of the field are particularly welcome in this collection.
Essential Aspects Of Immunometabolism In Health And Disease
DOWNLOAD
Author : Niels Olsen Saraiva Camara
language : en
Publisher: Springer Nature
Release Date : 2021-10-21
Essential Aspects Of Immunometabolism In Health And Disease written by Niels Olsen Saraiva Camara and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-21 with Medical categories.
Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
Chromatin Regulation In Cell Fate Decisions
DOWNLOAD
Author : José Luis Sardina
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-20
Chromatin Regulation In Cell Fate Decisions written by José Luis Sardina and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Science categories.
Reprogramming The Cellular Molecular And Metabolic Architecture Of The Tumor Microenvironment For Effective Cancer Immunotherapy
DOWNLOAD
Author : Soumen Chakraborty
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-16
Reprogramming The Cellular Molecular And Metabolic Architecture Of The Tumor Microenvironment For Effective Cancer Immunotherapy written by Soumen Chakraborty and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-16 with Medical categories.