Role Of The P2x7 Nucleotide Receptor In Lipopolysaccharide Stimulated Macrophage Activation
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Role Of The P2x7 Nucleotide Receptor In Lipopolysaccharide Stimulated Macrophage Activation
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Author : Philip L. Fisette
language : en
Publisher:
Release Date : 1999
Role Of The P2x7 Nucleotide Receptor In Lipopolysaccharide Stimulated Macrophage Activation written by Philip L. Fisette and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
The Role Of P2 Pruinergic Receptors In Lipopolysaccharide Mediated Macrophage Activation And Pathophysiology
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Author : Alma N. Guerra
language : en
Publisher:
Release Date : 2002
The Role Of P2 Pruinergic Receptors In Lipopolysaccharide Mediated Macrophage Activation And Pathophysiology written by Alma N. Guerra and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
P2x7 Purinergic Receptor Modulation Of Lipopolysaccharide Stimulated Macrophage Activation
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Author : Julie A. Sommer
language : en
Publisher:
Release Date : 2001
P2x7 Purinergic Receptor Modulation Of Lipopolysaccharide Stimulated Macrophage Activation written by Julie A. Sommer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Genetics Neurology Behavior And Diet In Parkinson S Disease
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Author : Colin R Martin
language : en
Publisher: Academic Press
Release Date : 2020-08-13
Genetics Neurology Behavior And Diet In Parkinson S Disease written by Colin R Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-13 with Medical categories.
Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease
M1 M2 Macrophages The Arginine Fork In The Road To Health And Disease
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Author : Charles Dudley Mills
language : en
Publisher: Frontiers Media SA
Release Date : 2015-03-23
M1 M2 Macrophages The Arginine Fork In The Road To Health And Disease written by Charles Dudley Mills and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-23 with Immunologic diseases categories.
Macrophages have unique and diverse functions necessary for survival. And, in humans (and other species), they are the most abundant leukocytes in tissues. The Innate functions of macrophages that are best known are their unusual ability to either “Kill” or “Repair”. Since killing is a destructive process and repair is a constructive process, it was stupefying how one cell could exhibit these 2 polar – opposite functions. However, in the late 1980’s, it was shown that macrophages have a unique ability to enzymatically metabolize Arginine to Nitric Oxide (NO, a gaseous non – specific killer molecule) or to Ornithine (a precursor of polyamines and collagen for repair). The dual Arginine metabolic capacity of macrophages provided a functional explanation for their ability to kill or repair. Macrophages predominantly producing NO are called M1 and those producing Ornithine are called M2. M1 and M2 – dominant responses occur in lower vertebrates, and in T cell deficient vertebrates being directly driven by Damage and Pathogen Associated Molecular Patterns (DAMP and PAMP). Thus, M1 and M2 are Innate responses that protect the host without Adaptive Immunity. In turn, M1/M2 is supplanting previous models in which T cells were necessary to “activate” or “alternatively activate” macrophages (the Th1/Th2 paradigm). M1 and M2 macrophages were named such because of the additional key findings that these macrophages stimulate Th1 and Th2 – like responses, respectively. So, in addition to their unique ability to kill or repair, macrophages also govern Adaptive Immunity. All of the foregoing would be less important if M1 or M2 – dominant responses were not observed in disease. But, they are. The best example to date is the predominance of M2 macrophages in human tumors where they act like wound repair macrophages and actively promote growth. More generally, humans have become M2 – dominant because sanitation, antibiotics and vaccines have lessened M1 responses. And, M2 dominance seems the cause of ever - increasing allergies in developed countries. Obesity represents a new and different circumstance. Surfeit energy (e.g., lipoproteins) causes monocytes to become M1 dominant in the vessel walls causing plaques. Because M1 or M2 dominant responses are clearly causative in many modern diseases, there is great potential in developing the means to selectively stimulate (or inhibit) either M1 or M2 responses to kill or repair, or to stimulate Th1 or Th2 responses, depending on the circumstance. The contributions here are meant to describe diseases of M1 or M2 dominance, and promising new methodologies to modulate the fungible metabolic machinery of macrophages for better health.
Seldin And Giebisch S The Kidney
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Author : Robert J. Alpern
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Seldin And Giebisch S The Kidney written by Robert J. Alpern and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
A classic nephrology reference for over 25years, Seldin and Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch’s The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions
T Cell Differentiation And Function In Tissue Inflammation
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Author : Amit Awasthi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-11
T Cell Differentiation And Function In Tissue Inflammation written by Amit Awasthi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with categories.
Role Of The P2rx7 Nucleotide Receptor In Transcriptional Activation Of Monocytic Cells
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Author : Monica Lynn Gavala
language : en
Publisher:
Release Date : 2008
Role Of The P2rx7 Nucleotide Receptor In Transcriptional Activation Of Monocytic Cells written by Monica Lynn Gavala and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2004
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Dissertations, Academic categories.