Sickle Cell Simply Explained

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Sickle Cell Simply Explained

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Author : Dr. John Koramoa
language : en
Publisher: Author House
Release Date : 2014

Sickle Cell Simply Explained written by Dr. John Koramoa and has been published by Author House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Health & Fitness categories.

Sickle cell disease is the most common genetic disease world-wide. For a person to suffer the disease, he or she has to inherit the faulty gene from each parent. It affects millions of people in the world. It is a chronic illness of serious proportions. Medical, psychological and socioeconomic consequences place a great burden on sufferers and their Carers. In the past sufferers of sickle cell anaemia survived for a few years only.When only one sickle cell gene is inherited by a person with normal haemoglobin, the condition is referred to as the carrier state or the trait. Individuals with the trait have no medical problems under normal conditions of life. This is how the gene has been able to survive and be passed on from generation to generation. The trait can thus have serious implications for marriage and childbearing. It is therefore, imperative for people intending to have children to know about it in order to help prevent the disease. Sickle cell disease which was once thought to be restricted to only a few areas, especially among Black people, is now known to be world-wide. It has been described as a world health problem.This book provides information in an easily readable format for everybody to understand sickle cell and its related conditions. There is the need for greater awareness and knowledge of the disease and the trait to avoid confusion, misunderstanding and myths, which hamper their proper management and prevention. At present there is no readily available cure for sickle cell disease. However, with proper management of the many ill-effects of the disease, sufferers can be assisted to live comfortable lives and for many years. Life-style measures are paramount and are referred to in some detail in the book. It is a great resource."

Sickle Cell Simply Explained

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Author : Dr. John Koramoa
language : en
Publisher: AuthorHouse
Release Date : 2014-04-11

Sickle Cell Simply Explained written by Dr. John Koramoa and has been published by AuthorHouse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-11 with Health & Fitness categories.

Sickle cell disease is the most common genetic disease world-wide. For a person to suffer the disease, he or she has to inherit the faulty gene from each parent. It affects millions of people in the world. It is a chronic illness of serious proportions. Medical, psychological and socioeconomic consequences place a great burden on sufferers and their Carers. In the past sufferers of sickle cell anaemia survived for a few years only. When only one sickle cell gene is inherited by a person with normal haemoglobin, the condition is referred to as the carrier state or the trait. Individuals with the trait have no medical problems under normal conditions of life. This is how the gene has been able to survive and be passed on from generation to generation. The trait can thus have serious implications for marriage and childbearing. It is therefore, imperative for people intending to have children to know about it in order to help prevent the disease. Sickle cell disease which was once thought to be restricted to only a few areas, especially among Black people, is now known to be world-wide. It has been described as a world health problem. This book provides information in an easily readable format for everybody to understand sickle cell and its related conditions. There is the need for greater awareness and knowledge of the disease and the trait to avoid confusion, misunderstanding and myths, which hamper their proper management and prevention. At present there is no readily available cure for sickle cell disease. However, with proper management of the many ill-effects of the disease, sufferers can be assisted to live comfortable lives and for many years. Life-style measures are paramount and are referred to in some detail in the book. It is a great resource.

My Dna Diary

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Author : Lisa Mullan
language : en
Publisher:
Release Date : 2019-10-31

My Dna Diary written by Lisa Mullan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-31 with Juvenile Nonfiction categories.

Have you heard of DNA? There's me, Alina and my three friends. Oh, and lots of cousins. How we live our life affects how you live yours. It's called genetics and this book will show you how it works. A gentle introduction to genes, chromosomes, inheritance, oxygen transport and sickle cell anaemia for 9-12 year-olds.

Sickle Cell Pain

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Author : Samir K. Ballas
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2015-06-01

Sickle Cell Pain written by Samir K. Ballas and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Medical categories.

Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.

Iron Chelation Therapy

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Author : Chaim Hershko
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Iron Chelation Therapy written by Chaim Hershko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Evidence Based Management Of Sickle Cell Disease

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Author : M D George R Buchanan
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2014-09-09

Evidence Based Management Of Sickle Cell Disease written by M D George R Buchanan and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Sickle cell anemia categories.

Sickle cell disease can be severe and disabling. When properly treated, patients live longer and with better quality life. This is a US government publication intended to provide evidence-based guidelines for the care of these patients for the use of all concerned providers as well as patients and family members. This book is available in print here for convenience.

Sickle What 6 X 9

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Author :
language : en
Publisher:
Release Date : 2019-06-15

Sickle What 6 X 9 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-15 with categories.

A perfect beginning to anyone's first education about sickle cell disease (SCD), this book lays the foundation for basic knowledge about SCD, what it is, how it works and most importantly how to handle the news of a new sickle cell diagnosis. ALSO AVAILABLE IN AN E-BOOK EDITION! Sickle What? is an educational book written in simple language with helpful illustrations to explain complex medical concepts and terminology. Sickle What? arms patients and parents of newly diagnosed children with the knowledge they need to understand and manage sickle cell disease (SCD).

The Management Of Sickle Cell Disease

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Author : U. S. Department of Health
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2002

The Management Of Sickle Cell Disease written by U. S. Department of Health and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Sickle cell anemia categories.

#1 Best Seller on Sickle Cell Disease (SCD). Sickle cell disease is a group of blood disorders passed down from parents to children. Sickle cell anemia shortens life expectancy by 30 years via bacterial infections, painful swellings, fever, arthritis, leg ulcers, eye, lung & heart damage. Over 100,000 people, mostly African-Americans, in the United States have sickle cell disease. Over 2 million people have sickle cell trait in America. It is estimated that more than 300,000 children are born each year with SCD around the world. This edition of The Management of Sickle Cell Disease (SCD) is organized into four parts: 1. Diagnosis and Counseling 2. Health Maintenance 3. Treatment of Acute and Chronic Complications 4. Special Topics. The original intent was to incorporate evidence-based medicine into each chapter, but there was variation among evidence-level scales, and some authors felt recommendations could be made, based on accepted practice, without formal trials in this rare disorder. The best evidence still is represented by randomized, controlled trials (RCTs), but variations exist in their design, conduct, endpoints, and analyses. It should be emphasized that selected people enter a trial, and results should apply in practice specifically to populations with the same characteristics as those in the trial. Randomization is used to reduce imbalances between groups, but unexpected factors sometimes may confound analysis or interpretation. In addition, a trial may last only a short period of time, but long-term clinical implications may exist. Another issue is treatment variation, for example, a new pneumococcal vaccine developed after the trial, which has not been tested formally in a sickle cell population. Earlier trial results may be accepted, based on the assumption that the change is small. In some cases, RCTs cannot be done satisfactorily (e.g., for ethical reasons, an insufficient number of patients, or a lack of objective measures for sickle cell "crises"). Thus the bulk of clinical experience in SCD still remains in the moderately strong and weaker categories of evidence. Not everyone has an efficacious outcome in a clinical trial, and the frequency of adverse events, such as with long-term transfusion programs or hematopoietic transplants, might not be considered. Thus, an assessment of benefit-to-risk ratio should enter into translation of evidence levels into practice recommendations. A final issue is that there may be two alternative approaches that are competitive (e.g., transfusions and hydroxyurea). In this case the pros and cons of each course of treatment should be discussed with the patient. This book is B&W copy of the government agency publication.

Benign Hematologic Disorders In Children

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Author : Deepak M. Kamat
language : en
Publisher: Springer Nature
Release Date : 2020-08-18

Benign Hematologic Disorders In Children written by Deepak M. Kamat and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Medical categories.

This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell disorders, and coagulation disorders. The sixth and seventh sections discuss neonatal hematology and bone marrow failure syndrome. The eighth section reviews supportive care, while the final section covers miscellaneous subjects including pediatric vascular anomalies and complement dysregulation syndromes. Written by experts in the field, Benign Hematologic Disorders in Children: A Clinical Guide is a valuable resource for clinicians and practitioners who treat children afflicted with these disorders.

Sickle Cell Anemia

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Author : Fernando Ferreira Costa
language : en
Publisher: Springer
Release Date : 2016-03-29

Sickle Cell Anemia written by Fernando Ferreira Costa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-29 with Medical categories.

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.