Single Molecule Detection In Solution
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Single Molecule Detection In Solution
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Author : Christoph Zander
language : en
Publisher: Wiley-VCH
Release Date : 2002-05-06
Single Molecule Detection In Solution written by Christoph Zander and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-05-06 with Science categories.
The detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years. This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results. This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme.
Single Molecule Optical Detection Imaging And Spectroscopy
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Author : W. E. Moerner
language : de
Publisher: John Wiley & Sons
Release Date : 2008-09-26
Single Molecule Optical Detection Imaging And Spectroscopy written by W. E. Moerner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Science categories.
Single Molecule Spectroscopy is one of the hottest topics in today's chemistry. It brings us close to the the most exciting vision generations of chemists have been dreaming of: To observe and examine single molecules! While most of chemistry deals with myriads of molecules, this books presents the latest developments for the detection and investigation of single entities. Written by internationally renowned authors, it is a thorough and comprehensive survey of current methods and their applications.
Single Molecule Spectroscopy
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Author : R. Rigler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Single Molecule Spectroscopy written by R. Rigler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.
Handbook Of Single Molecule Fluorescence Spectroscopy
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Author : Chris Gell
language : en
Publisher: OUP Oxford
Release Date : 2006-08-17
Handbook Of Single Molecule Fluorescence Spectroscopy written by Chris Gell and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-17 with Science categories.
Analytical measurements at the single molecule level under ambient conditions have become almost routine in the past few years. The application of this technology to fundamental studies of heterogeneity in biomolecular structure and dynamics, chemical and biological reaction kinetics, and photophysics provides a rich playground for molecular scientists. The potential use of single molecule detection for nanotechnology and quantum information processing is a new and almost unexplored area. This handbook is intended for those interested in a practical introduction to single molecule investigations using fluorescence techniques and places special emphasis on the practicalities of achieving single molecule resolution, analysing the resulting data and exploration of the applications in biophysics. It is ideal for graduate research students and others embarking on work in this exciting field.
Ultrasensitive And Single Molecule Detection Technologies
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Author :
language : en
Publisher:
Release Date : 2007
Ultrasensitive And Single Molecule Detection Technologies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Biomolecules categories.
Single Molecule Analysis
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Author : Iddo Heller
language : en
Publisher: Springer Nature
Release Date : 2023-11-13
Single Molecule Analysis written by Iddo Heller and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-13 with Science categories.
This third edition volume expands on the previous editions with new discussions on the latest techniques and developments in the field. The chapters in this book are organized into four parts, and cover topics such as optical tweezers; single-molecule fluorescence tools; atomic force microscopy; magnetic tweezers; applications to virus protein shells, unfolding of proteins, nucleic acids, motor proteins, in vivo and in vitro; and protocols to establish specific surface interactions and perform force calibration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Single Molecule Analysis: Methods and Protocols, Third Edition is a valuable resource for all researchers who want to learn more about this exciting and still expanding field. Chapters 2, 7, 8, 9, 12, 18, and 19 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Single Molecule Detection Of Near Infrared Phthalocyanine Dyes
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Author : You Li
language : en
Publisher:
Release Date : 2009
Single Molecule Detection Of Near Infrared Phthalocyanine Dyes written by You Li and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
The major advantage associated with near-infrared monitoring is the fact that few compounds show intrinsic fluorescence in this region of the spectrum and hence background from other molecules is reduced. Phthalocyanine dyes provide emission at deep red and near infrared wavelengths but have excellent photostability and hence are an attractive candidate for near-infrared fluorescence bioassay applications. However, because of their small Stokes shifts, non-standard methods are needed for optimum separation of fluorescence from scattered laser light. This thesis reports the development of a custom confocal microscope that uses a lowcost laser diode operating at 667 nm for sample excitation and an angle-tuned Raman notch filter to block scattered laser radiation and provide high-throughput of fluorescence with small Stokes shift. Also, a diffraction grating is used to isolate the laser excitation wavelength from the broadband luminescence of the laser. The experimental system is used to observe photon bursts from single molecules of zinc phthalocyanine fluorophores in an ethanol solution. The autocorrelation function of the photon trace, which is measured in fluorescence correlation spectroscopy, provides a measure of the presence of photon bursts from single molecules. Experiments to characterize the limits of detection of near-infrared fluorophores in aqueous solution using the microscope are also discussed.
Single Molecules And Nanotechnology
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Author : Rudolf Rigler
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-07
Single Molecules And Nanotechnology written by Rudolf Rigler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-07 with Technology & Engineering categories.
This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including quantum photonics of organic dyes and inorganic nanoparticles and monitoring of single molecule (enzymatic) reactions.
Spectroscopy And Dynamics Of Single Molecules
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Author :
language : en
Publisher: Elsevier
Release Date : 2019-08-14
Spectroscopy And Dynamics Of Single Molecules written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-14 with Science categories.
Spectroscopy and Dynamics of Single Molecules: Methods and Applications reviews the most recent developments in spectroscopic methods and applications. Spectroscopic techniques are the chief experimental methods for testing theoretical models and research in this area plays an important role in stimulating new theoretical developments in physical chemistry. This book provides an authoritative insight into the latest advances in the field, highlighting new techniques, current applications, and potential future developments An ideal reference for chemists and physicists alike, Spectroscopy and Dynamics of Single Molecules: Methods and Applications is a useful guide for all those working in the research, design, or application of spectroscopic tools and techniques across a wide range of fields. Includes the latest research on ultrafast vibrational and electronic dynamics, nonlinear spectroscopies, and single-molecule methods Makes the content accessible to researchers in chemistry, biophysics, and chemical physics through a rigorous multi-disciplinary approach Provides content edited by a world-renowned chemist with more than 30 years of experience in research and instruction
New Frontiers In Ultrasensitive Bioanalysis
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Author : Xiao-Hong Nancy Xu
language : en
Publisher: John Wiley & Sons
Release Date : 2007-06-04
New Frontiers In Ultrasensitive Bioanalysis written by Xiao-Hong Nancy Xu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-04 with Science categories.
An overview of current research and developments in ultrasensitive bioanalysis New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.