Skin Permeability
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Skin Permeability
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Author : H. Schaefer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-01
Skin Permeability written by H. Schaefer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-01 with Medical categories.
Skin Permeability
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Author : Hans Schaefer
language : en
Publisher: Springer Verlag
Release Date : 1982-01-01
Skin Permeability written by Hans Schaefer and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-01-01 with Medical categories.
Skin Permeation
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Author : Joel L. Zatz
language : en
Publisher:
Release Date : 1993
Skin Permeation written by Joel L. Zatz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds
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Author : Kenji Sugibayashi
language : en
Publisher: Springer
Release Date : 2017-11-28
Skin Permeation And Disposition Of Therapeutic And Cosmeceutical Compounds written by Kenji Sugibayashi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-28 with Medical categories.
This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and disposition of entrapped active ingredients through and into the skin. Skin permeation, disposition, and metabolism of chemicals are first summarized in the general introduction. Then primary topical formulations are explained in the second part, “Basic Formulations Applied to Skin”. The explanation for the active compounds and formulations are of the most important parts required to fabricate these formulations. Skin absorption of chemicals is generally much lower than oral and the other mucosal absorptions, so that skin-penetration enhancement is a key issue to have good formulations topically applied. Part 3 presents “Skin Penetration Enhancement”. In addition, Part 4, “Selection of Topically Applied Chemical Candidates”, deals with selection methods of topically applied ingredients for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Parts 5 and 6, “Safety Assessment of Topically Applied Compounds“ and “Experimental Methods of Skin Permeation“, respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists. Their comments are especially helpful for pharmaceutical and cosmetic researchers who study dermatopharmacokinetics and topical formulations. This volume is particularly useful for those working in R&D, graduate students, and educators in the area of pharmaceutics, cosmetic sciences, dermatological sciences, pharmacology, toxicology, biopharmacy, pharmacokinetics, physical pharmacy, chemical engineering, and related fields.
Predictive Methods In Percutaneous Absorption
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Author : Gary P. Moss
language : en
Publisher: Springer
Release Date : 2015-07-01
Predictive Methods In Percutaneous Absorption written by Gary P. Moss and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-01 with Medical categories.
This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.
Enhancement Of Skin Permeability By 1 Dodecylazacycloheptan 2 One
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Author : SUI YUEN EDDIE HOU
language : en
Publisher:
Release Date : 1987
Enhancement Of Skin Permeability By 1 Dodecylazacycloheptan 2 One written by SUI YUEN EDDIE HOU and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
shortened with permission of author.)
Skin Barrier
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Author : Hans Schaefer
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1996
Skin Barrier written by Hans Schaefer and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Skin Barrier is the first book to be written exclusively by researchers for researchers as a convenient desktop reference. It focuses on several key aspects of the skin barrier including composition and structure and a description of the properties governing the diffusion of compounds across the skin. Although there has been a large number of laboratories involved in measuring percutaneous absorption over the past 15 to 20 years, it is only recently that there has been a general consensus in the scientific community regarding the development of standard protocols. Recognizing the importance of this, the authors have included two chapters detailing the protocol used in measuring and predicting percutaneous absorption and a discussion on the practical application of these techniques to solve associated problems. In order to provide the researcher and especially the student with access to more detailed information, the book features a comprehensive listing of references published over the past 10 years. Skin Barrier is the only desktop reference for dermatologists, cosmetologists, biochemists, biologists, and those in the pharmaceutics industry, who need detailed and accurate information about the skin barrier on a daily basis. No R & D department should be without a copy.
Thermotropic Effects On Skin Permeability
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Author : EDWARDS EON-CHAO LINN
language : en
Publisher:
Release Date : 1982
Thermotropic Effects On Skin Permeability written by EDWARDS EON-CHAO LINN and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Burns and scalds categories.
transfer. The data suggest specific thermally induced phase transitions in the skin's horny element open to skin to diffusion of these species.
Dermal Absorption
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Author : J. Kielhorn
language : en
Publisher: World Health Organization
Release Date : 2006
Dermal Absorption written by J. Kielhorn and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations.
Percutaneous Penetration Enhancers Drug Penetration Into Through The Skin
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Author : Nina Dragicevic
language : en
Publisher: Springer
Release Date : 2017-05-04
Percutaneous Penetration Enhancers Drug Penetration Into Through The Skin written by Nina Dragicevic and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-04 with Medical categories.
Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists.