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Small Gtpases In Disease Part A


Small Gtpases In Disease Part A
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Small Gtpases In Disease Part A


Small Gtpases In Disease Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-09-02

Small Gtpases In Disease Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.


The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volumes 1 onwards. For more information about the Elsevier Book Series on ScienceDirect Program, please visit: http://www.info.sciencedirect.com/bookseries/ This volume is the first of two planned volumes on the topic of small GTPases and their role in disease.



Small Gtpases In Disease Part B


Small Gtpases In Disease Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2008-04-01

Small Gtpases In Disease Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-01 with Science categories.


The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volume 1 onward.



Small Gtpases In Disease B


Small Gtpases In Disease B
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Author : William E. Balch
language : en
Publisher: Academic Press
Release Date : 2008

Small Gtpases In Disease B written by William E. Balch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.




Regulators And Effectors Of Small Gtpases Part D Rho Family


Regulators And Effectors Of Small Gtpases Part D Rho Family
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Author :
language : en
Publisher: Elsevier
Release Date : 2000-10-11

Regulators And Effectors Of Small Gtpases Part D Rho Family written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-10-11 with Medical categories.


This volume and its companions (Volumes 255, 256, 257, and the forthcoming 329) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.



Rho Gtpases Molecular Biology In Health And Disease


Rho Gtpases Molecular Biology In Health And Disease
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Author : Philippe Fort
language : en
Publisher: World Scientific
Release Date : 2017-12-12

Rho Gtpases Molecular Biology In Health And Disease written by Philippe Fort and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-12 with Science categories.


Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progression or apoptosis. In view of such pleiotropic activities, Rho-controlled signaling has proven to be of medical relevance, especially in tumorigenesis, disease-associated bone remodeling and infectiology.This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis.This updated review on the biology of Rho GTPases is an essential read for molecular and cell biologists. It is also an invaluable guide to post-graduate and medical students who wish to deepen their knowledge in cell biology.



Autophagy In Disease And Clinical Applications Part C


Autophagy In Disease And Clinical Applications Part C
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Author : Daniel Klionsky
language : en
Publisher: Academic Press
Release Date : 2009-03-10

Autophagy In Disease And Clinical Applications Part C written by Daniel Klionsky and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-10 with Science categories.


The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one of the leading authorities in the field, this volume and its companion volumes, Autophagy: Lower Eukaryotes and Autophagy in Mammalian Systems, provide a comprehensive overview of the techniques involved in studying autophagy in eukaryotes and simple animal systems, mammalian cells and non-human animals, and humans. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning in the cell is called autophagy – literally self-eating. In the future, research in this field will help to design clinical approaches that can turn on autophagy and halt tumor growth. Provides an overview of autophagy in regards to humans, specifically regarding disease connections and clinical samples Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture Presents reliable methods that, in this relatively new field, allow the reader to find appropriate techniques to identify, monitor, and quantify autophagic processes



Cilia Part A


Cilia Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-03-12

Cilia Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Science categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium



Synthetic Biology Part A


Synthetic Biology Part A
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Author : Chris Voigt
language : en
Publisher: Academic Press
Release Date : 2011-07-08

Synthetic Biology Part A written by Chris Voigt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-08 with Science categories.


Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. Encompasses a variety of different approaches, methodologies and disciplines Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation



Biothermodynamics Part A


Biothermodynamics Part A
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Author : Michael L. Johnson
language : en
Publisher: Academic Press
Release Date : 2009-03-14

Biothermodynamics Part A written by Michael L. Johnson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-14 with Science categories.


In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an “energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.



Nucleosomes Histones And Chromatin Part A


Nucleosomes Histones And Chromatin Part A
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Author : Carl Wu
language : en
Publisher: Academic Press
Release Date : 2012-08-31

Nucleosomes Histones And Chromatin Part A written by Carl Wu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-31 with Medical categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 2 volumes covering nucleosomes, histones and chromatin, it has chapters on methods applied to the study of protein arginine methylation, high-resolution identification of intra- and interchromosomal DNA interactions by 4C technology, and peptide arrays to interrogate the binding specificity of chromatin-binding proteins. Continues the legacy of this premier serial by containing quality chapters authored by leaders in the field The first of 2 volumes covering nucleosomes, histones and chromatin Chapters on methods applied to the study of protein arginine methylation, high-resolution identification of intra- and interchromosomal DNA interactions by 4C technology, and peptide arrays to interrogate the binding specificity of chromatin-binding proteins