Smith And Williams Introduction To The Principles Of Drug Design
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Smith And Williams Introduction To The Principles Of Drug Design And Action
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Author : H. Jphn Smith
language : en
Publisher: CRC Press
Release Date : 2005-10-10
Smith And Williams Introduction To The Principles Of Drug Design And Action written by H. Jphn Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-10 with Medical categories.
Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest informatio
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 1998-05-15
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-05-15 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Introduction To The Principles Of Drug Design
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Author : H. J. Smith
language : en
Publisher: Elsevier
Release Date : 2016-06-14
Introduction To The Principles Of Drug Design written by H. J. Smith and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-14 with Medical categories.
Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of drugs. Organized into nine chapters, this book begins with an overview of how the body handles a drug in terms of absorption, metabolism, distribution, and excretion. This text then examines the critical drug activity at the receptor site, which is usually related to blood and other distribution fluid levels. Other chapters consider the factors involved in binding a drug, metabolite, or substrate to a receptor. The final chapter deals with the design of chemotherapeutic agent for clinical use in the treatment of human infections. This book is intended for use in undergraduate pharmacy courses in medicinal chemistry and as an aid in similar courses in biochemistry and pharmacology. Graduates in chemistry just entering the pharmaceutical industry will also find this book useful.
Smith And Williams Introduction To The Principles Of Drug Design
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Author : H. J. Smith
language : en
Publisher:
Release Date : 1988
Smith And Williams Introduction To The Principles Of Drug Design written by H. J. Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Drugs categories.
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-04-28
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-28 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Smith And Williams Introduction To The Principles Of Drug Design
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Author : H. J. Smith
language : en
Publisher:
Release Date : 1988-01-01
Smith And Williams Introduction To The Principles Of Drug Design written by H. J. Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Pharmacology categories.
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-11-11
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-11 with Medical categories.
As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, 4th Edition provides an introduction to the principles of rational drug design, including both novel and established approaches. This new edition adopts a 'from-bench-to-marketplace' approach, using real examples where possible. In addition to a comprehensive update of the previous edition, new advances in molecular techniques, biotechnological applications and computer-aided design have been added.
Foye S Principles Of Medicinal Chemistry
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Author : David A. Williams
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2002
Foye S Principles Of Medicinal Chemistry written by David A. Williams and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.
Chemotherapeutic Targets In Parasites
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Author : Tag E. Mansour
language : en
Publisher: Cambridge University Press
Release Date : 2002-11-04
Chemotherapeutic Targets In Parasites written by Tag E. Mansour and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-04 with Science categories.
Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry.
Analogue Based Drug Discovery Iii
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Author : János Fischer
language : en
Publisher: John Wiley & Sons
Release Date : 2012-10-15
Analogue Based Drug Discovery Iii written by János Fischer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-15 with Medical categories.
Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and -- together with the previous volumes -- constitutes the first systematic approach to drug analogue development.