Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition
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Smith And Williams Introduction To The Principles Of Drug Design And Action
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Author : H. Jphn Smith
language : en
Publisher: CRC Press
Release Date : 2005-10-10
Smith And Williams Introduction To The Principles Of Drug Design And Action written by H. Jphn Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-10 with Medical categories.
Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest informatio
Smith And Williams Introduction To The Principles Of Drug Design And Action
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2005-10-10
Smith And Williams Introduction To The Principles Of Drug Design And Action written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-10 with Medical categories.
Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest informatio
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-11-11
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-11 with Medical categories.
As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, 4th Edition provides an introduction to the principles of rational drug design, including both novel and established approaches. This new edition adopts a 'from-bench-to-marketplace' approach, using real examples where possible. In addition to a comprehensive update of the previous edition, new advances in molecular techniques, biotechnological applications and computer-aided design have been added.
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 1998-05-15
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-05-15 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Introduction To The Principles Of Drug Design
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Author : H. J. Smith
language : en
Publisher: Elsevier
Release Date : 2016-06-14
Introduction To The Principles Of Drug Design written by H. J. Smith and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-14 with Medical categories.
Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of drugs. Organized into nine chapters, this book begins with an overview of how the body handles a drug in terms of absorption, metabolism, distribution, and excretion. This text then examines the critical drug activity at the receptor site, which is usually related to blood and other distribution fluid levels. Other chapters consider the factors involved in binding a drug, metabolite, or substrate to a receptor. The final chapter deals with the design of chemotherapeutic agent for clinical use in the treatment of human infections. This book is intended for use in undergraduate pharmacy courses in medicinal chemistry and as an aid in similar courses in biochemistry and pharmacology. Graduates in chemistry just entering the pharmaceutical industry will also find this book useful.
Smith And Williams Introduction To The Principles Of Drug Design
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Author : H. J. Smith
language : en
Publisher:
Release Date : 1988
Smith And Williams Introduction To The Principles Of Drug Design written by H. J. Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Drugs categories.
A Textbook Of Fundamentals Of Medicinal Chemistry
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Author : Dr. Somashekhar M. Metri
language : en
Publisher: JEC PUBLICATION
Release Date :
A Textbook Of Fundamentals Of Medicinal Chemistry written by Dr. Somashekhar M. Metri and has been published by JEC PUBLICATION this book supported file pdf, txt, epub, kindle and other format this book has been release on with Juvenile Nonfiction categories.
The "A Textbook of Fundamentals of Medicinal Chemistry", as an interdisciplinary science, merges principles of chemistry, biology, and pharmacology to discover, design, and develops therapeutic agents. The purpose of this text is to provide a comprehensive overview of the fundamentals of medicinal chemistry, emphasizing the relationship between chemical properties and biological actions of drugs. From historical developments to modern advances, such as QSAR and molecular modeling, each chapter aims to bridge traditional concepts with innovative techniques in drug design and development. The initial chapters cover general principles, including drug metabolism and physico-chemical properties affecting biological function. Subsequent sections delve into specific drug classes— adrenergic and cholinergic agents, CNS-active drugs, cardiovascular drugs, and antihistamines—focusing on their mechanisms, therapeutic actions, and structural attributes. Later chapters introduce antibiotics, antineoplastic agents, and anti-infective drugs, exploring their pharmacodynamics and the development of drug resistance. In addition, the book discusses agents acting on the endocrine system, anti-diabetics, local anesthetics, and agents for treating conditions like protozoal infections and helminthiasis. The text also delves into sulphonamides and drug design methodologies, such as pharmacophore modeling and combinatorial chemistry, presenting the tools and strategies essential in modern medicinal chemistry research. This text serves as a resource for B Pharmacy students, researchers, and professionals seeking to deepen their understanding of Fundamentals of medicinal chemistry and its applications in developing effective therapeutic agents. -Dr. Somashekhar M. Metri -Mr. Shivanand Kolageri -Dr. Vishal Bharat Babar, -Dr. Pratik Praksh Maske -Dr. A.R. Mahesh -Dr. Pramila.T, -Ms. Maharani H. Bhandarakavathe
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-04-28
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-28 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Chemistry And Pharmacology Of Anticancer Drugs
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Author : David E. Thurston
language : en
Publisher: CRC Press
Release Date : 2006-11-22
Chemistry And Pharmacology Of Anticancer Drugs written by David E. Thurston and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Medical categories.
While drug therapies developed in the last 50 years have markedly improved the management of some types of cancers, treatment outcomes, and drug side-effects for the most common types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells.
Kimia Medisinal 1 Edisi 2
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Author : Ed. Siswandono
language : id
Publisher: Airlangga University Press
Release Date : 2020-01-14
Kimia Medisinal 1 Edisi 2 written by Ed. Siswandono and has been published by Airlangga University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-14 with Medical categories.
Penulis : Siswanono ISBN : 978-602-0820-66-8 Tahun terbit : 2016 Bahasa : Indonesia Sampul : Soft Cover Ukuran : 15,8 x 23 cm Jumlah halaman : 590 hal Dalam buku Kimia Medisinal 1 ed 2 ini secara umum dibahas proses pengembangan obat yang terkini, peran struktur kimia, sifat kimia fisika terhadap proses absorpsi obat ke tubuh, distribusi obat dalam tubuh, kemungkinan interaksi obat dengan resptor dan prosess ekskresi obat. Selain itu juga dibahas hubungan Struktur, sifat kimia fisika terhadap aktivitas biologis obat dan hubungan aspek stereokimia dengan aktivitas biologis. Juga dibahas peran protein, enzim dan reseptor terhadap aktivitas biologis dan hubungan struktur senyawa agonis dan antagonis. Hubungan struktur dengan proses interaksi obat-reseptor dan kekuatan yang terlibat dalam interaksi tersebut serta hubungan beberapa sifat kimia fisika dengan aktivitas biologis obat juga dibahas dalam buku ini.