Smith And Williams Introduction To The Principles Of Drug Design And Action
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Smith And Williams Introduction To The Principles Of Drug Design And Action
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Author : H. Jphn Smith
language : en
Publisher: CRC Press
Release Date : 2005-10-10
Smith And Williams Introduction To The Principles Of Drug Design And Action written by H. Jphn Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-10 with Medical categories.
Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest informatio
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 1998-05-15
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-05-15 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Smith And Williams Introduction To The Principles Of Drug Design
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Author :
language : en
Publisher:
Release Date : 1998
Smith And Williams Introduction To The Principles Of Drug Design written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Drugs categories.
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-04-28
Smith And Williams Introduction To The Principles Of Drug Design And Action Third Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-28 with Medical categories.
The third edition of this popular textbook builds on the excellent foundations laid down by the earlier editions. It provides a thorough introduction to the principles of rational drug design, adopting a 'from the bench to the market place' approach. As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated. The introductory text explains the principles of drug design using real examples. These illustrate the discovery of 'lead' compounds and their manipulation to produce non-toxic drug candidates that will be successfully metabolized to interact with target receptors in a predicted fashion. In addition to fully updating the contents of the previous edition, the Editor has included important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition
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Author : H. John Smith
language : en
Publisher: CRC Press
Release Date : 2004-11-11
Smith And Williams Introduction To The Principles Of Drug Design And Action Fourth Edition written by H. John Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-11 with Medical categories.
As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, 4th Edition provides an introduction to the principles of rational drug design, including both novel and established approaches. This new edition adopts a 'from-bench-to-marketplace' approach, using real examples where possible. In addition to a comprehensive update of the previous edition, new advances in molecular techniques, biotechnological applications and computer-aided design have been added.
A Textbook Of Fundamentals Of Medicinal Chemistry
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Author : Dr. Somashekhar M. Metri
language : en
Publisher: JEC PUBLICATION
Release Date :
A Textbook Of Fundamentals Of Medicinal Chemistry written by Dr. Somashekhar M. Metri and has been published by JEC PUBLICATION this book supported file pdf, txt, epub, kindle and other format this book has been release on with Juvenile Nonfiction categories.
The "A Textbook of Fundamentals of Medicinal Chemistry", as an interdisciplinary science, merges principles of chemistry, biology, and pharmacology to discover, design, and develops therapeutic agents. The purpose of this text is to provide a comprehensive overview of the fundamentals of medicinal chemistry, emphasizing the relationship between chemical properties and biological actions of drugs. From historical developments to modern advances, such as QSAR and molecular modeling, each chapter aims to bridge traditional concepts with innovative techniques in drug design and development. The initial chapters cover general principles, including drug metabolism and physico-chemical properties affecting biological function. Subsequent sections delve into specific drug classes— adrenergic and cholinergic agents, CNS-active drugs, cardiovascular drugs, and antihistamines—focusing on their mechanisms, therapeutic actions, and structural attributes. Later chapters introduce antibiotics, antineoplastic agents, and anti-infective drugs, exploring their pharmacodynamics and the development of drug resistance. In addition, the book discusses agents acting on the endocrine system, anti-diabetics, local anesthetics, and agents for treating conditions like protozoal infections and helminthiasis. The text also delves into sulphonamides and drug design methodologies, such as pharmacophore modeling and combinatorial chemistry, presenting the tools and strategies essential in modern medicinal chemistry research. This text serves as a resource for B Pharmacy students, researchers, and professionals seeking to deepen their understanding of Fundamentals of medicinal chemistry and its applications in developing effective therapeutic agents. -Dr. Somashekhar M. Metri -Mr. Shivanand Kolageri -Dr. Vishal Bharat Babar, -Dr. Pratik Praksh Maske -Dr. A.R. Mahesh -Dr. Pramila.T, -Ms. Maharani H. Bhandarakavathe
Foye S Principles Of Medicinal Chemistry
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Author : David A. Williams
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2002
Foye S Principles Of Medicinal Chemistry written by David A. Williams and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.
Chemistry And Pharmacology Of Anticancer Drugs
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Author : David E. Thurston
language : en
Publisher: CRC Press
Release Date : 2006-11-22
Chemistry And Pharmacology Of Anticancer Drugs written by David E. Thurston and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Medical categories.
While drug therapies developed in the last 50 years have markedly improved the management of some types of cancers, treatment outcomes, and drug side-effects for the most common types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells.
Analogue Based Drug Discovery Iii
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Author : János Fischer
language : en
Publisher: John Wiley & Sons
Release Date : 2012-10-15
Analogue Based Drug Discovery Iii written by János Fischer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-15 with Medical categories.
Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and -- together with the previous volumes -- constitutes the first systematic approach to drug analogue development.
Foye S Principles Of Medicinal Chemistry
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Author : Thomas L. Lemke
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008
Foye S Principles Of Medicinal Chemistry written by Thomas L. Lemke and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
The Sixth Edition of this well-known text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist. A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures. Case studies from previous editions and answers to this edition's case studies are available online at thePoint.