Sorting And Recycling Endosomes
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Sorting And Recycling Endosomes
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-09-14
Sorting And Recycling Endosomes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-14 with Science categories.
Sorting and Recycling Endosomes provides the latest information on endosomes, the receiving compartment for endocytosed cargos, and the donor compartment and sorting station for cargos designated to lysosomes, Golgi, or plasma membrane. In recent years, the importance of endosomes as a sorting and recycling compartment has become increasingly appreciated. As such, scientists from various fields of cell biology, membrane traffic, and beyond, see the needs to communicate and learn about the methods used to investigate the dynamics and functions of endosomes. This book brings together specialists from the field who contribute their expertise on a broad range of biomedical topics that will provide ideal reading for researchers interested in endosomal sorting and recycling. This volume covers the approaches necessary to study the key components that mediate the generation and transport of membrane-bounded carriers from the endosomes, and how membrane trafficking machinery is coordinated with cytoskeletons during these processes. In addition to studies carried out in mammalian cells, other model systems such as worm and yeast are also included. - Provides the latest information on endosomes, the receiving compartment for endocytosed cargos, and the donor compartment and sorting station for cargos designated to lysosomes, Golgi, or plasma membrane. - Covers an increasingly appreciated field in cell biology - Includes both established and new technologies - Brings together specialists from the field who contribute their expertise on a broad range of biomedical topics that will provide ideal reading for researchers interested in endosomal sorting and recycling
Endosomes
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Author : Ivan Dikic
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-07
Endosomes written by Ivan Dikic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-07 with Science categories.
Endosomes are a heterogeneous population of endocytic vesicles and tubules that have captivated the interest of biologists for many years, partly due to their important cellular functions and partly due to their intriguing nature and dynamics. Endosomes represent a fascinating interconnected network of thousands of vesicles that transport various cargoes, mainly proteins and lipids, to distant cellular destinations. How endosomes function, what co-ordinates the molecular determinants at each step of their dynamic life cycle and what their biological and medical relevance is, are among the questions addressed in this book.
Trafficking Inside Cells
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Author : Nava Segev
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-05-30
Trafficking Inside Cells written by Nava Segev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-30 with Science categories.
This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
Endocytic Components Identification And Characterization
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Author : J.J.M. Bergeron
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Endocytic Components Identification And Characterization written by J.J.M. Bergeron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
In step with the rapid growth of research into the biochemical and functional characterization of the endosome, Volume 19 surveys the recent advances in the methodological aspects of this field. Coverage includes the use of free flow electrophoresis to define endosome subpopulations, the endosomal compartments in rat hepatocytes, the role of endosomes in transmembrane signalling, and six additional articles.
Targeted Drug Delivery
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Author : Rudolph L. Juliano
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Targeted Drug Delivery written by Rudolph L. Juliano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic behavior, tissue distribution, and subcellular localization of pharmaco logically active agents, offers an important means for improving the efficacy of a wide variety of drug therapies. This is particularly true for therapeutic approaches based on newer agents which are the products of recombinant DNA research. These agents, be they peptides, proteins, or oligonucleotides, tend to be larger, more complex, and less stable than traditional drugs. Thus they stand to benefit most from drug delivery systems which can protect them from premature degradation and which can carry them to critical target sites in the body. This volume examines several important aspects of the current state of drug delivery research; it also attempts to project future directions for this field. Successful approaches to drug targeting are based, first of all, on a sophisticated understanding of the biological barriers encountered by the drug-carrier complex as it moves from the portal of administration to the ultimate target site. A second aspect of successful drug delivery is appro priate matching of the disease entity with the pharmacologically active substance and with the delivery system. Thus it is important to be aware of the variety of delivery technologies which currently exist and to be sensitive to their strengths and limitations.
Biology Of The Lysosome
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Author : John B. Lloyd
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biology Of The Lysosome written by John B. Lloyd and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Volume 27 provides a comprehensive review of current knowledge of lysosome function in mammalian cells. The book's unique contribution is its series of chapters that offers unparalleled treatment of the metabolic activities of lysosomes.
Intracellular Pathogens In Membrane Interactions And Vacuole Biogenesis
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Author : Jean-Pierre Gorvel
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-31
Intracellular Pathogens In Membrane Interactions And Vacuole Biogenesis written by Jean-Pierre Gorvel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-31 with Medical categories.
This book provides information on the molecular interactions between host cell organelles and pathogens, which have developed strategies to survive within infected cells. Chapters are grouped into five sections: I. Endocytosis and phagocytosis. Collectively, the chapters of this section review basic knowledge regarding intracellular organelles are involved in membrane interactions with pathogen-containing vacuoles. II. Professional and non-professional phagocytes. Here the authors describe the major differences between the two host cell types, which can be infected by microorganisms. III. Maturation pathways of bacteria-containing vacuoles. Molecular interactions between vacuoles and intracellular organelles leading to the search of the Holy Grail, the replication niche, are described. IV. Host response. Host cells are able to react against intruders and eventually mount host responses. In these chapters the various types of host response mechanisms against intracellular intruders are reviewed. V. Co-evolution. In these final chapters, the question is addressed of whether knowledge of bacteria-host cell interactions will be acquired fast enough to find the necessary tools for controlling microorganism development.
Retinal Degenerative Diseases
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Author : Matthew M. LaVail
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-21
Retinal Degenerative Diseases written by Matthew M. LaVail and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-21 with Medical categories.
This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.
Encyclopedia Of Cell Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-08-07
Encyclopedia Of Cell Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-07 with Science categories.
The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences
Gtpases Regulating Membrane Dynamics
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Author : W. E. Balch
language : en
Publisher: Gulf Professional Publishing
Release Date : 2005-12-13
Gtpases Regulating Membrane Dynamics written by W. E. Balch and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-13 with Science categories.
Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.