Surveying Antimicrobial Resistance The New Complexity Of The Problem

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Surveying Antimicrobial Resistance The New Complexity Of The Problem
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Author : Gilberto Igrejas
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-10
Surveying Antimicrobial Resistance The New Complexity Of The Problem written by Gilberto Igrejas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-10 with categories.
In January of 2015, under the 1st International Caparica Conference in Antibiotic Resistance, a Research Topic entitled: “Surveying Antimicrobial Resistance: Approaches, Issues, and Challenges to overcome”, was published (http://journal.frontiersin.org/researchtopic/3763/surveying-antimicrobial-resistanceapproaches- issues-and-challenges-to-overcome). The problem of antimicrobial resistance (AMR), caused by excessive and inappropriate use of antibiotics, is a public health issue that concerns us all. The introduction of penicillin in the 1940s, the start of the antibiotics era, has been recognized as one of the greatest advances in therapeutic medicine. However, according to the World Health Organization (WHO), AMR infections are now an increasing worldwide public health threat and a post-antibiotic era is imminent, where common infections and minor injuries could be fatal. AMR is a typical ‘One Health’ problem, in which livestock animals and the environment constitute AMR reservoirs and transmission routes to and from the human population. Without effective antimicrobials to counter and prevent infections, other major achievements in modern medicine, such as organ transplantation, cancer chemotherapy and major surgery, risk being compromised. AMR infections in animals have negative outcomes on animal health, welfare, biosecurity and production. In 2006, the ban of growth promoting antibiotics highlighted antibiotic use in animal production as a risk factor in the development of antibiotic resistant bacteria. Bacteria can be transferred to humans via several routes; consumption of animal products, exposure through contact with animals, and the contamination of ground and surface waters by animal waste products. Therefore, it is of utmost importance that antimicrobial use in animals is reduced to a minimum, without compromising animal health and welfare. Mechanisms of bacterial antibiotic resistance are classified according to the types of antibiotic molecules or their targets in the cell. Environmental antibiotic-resistance genes are spread then acquired by clinically relevant microorganisms. Many resistance genes are conveyed into pathogen genomes via mobile genetic elements such as plasmids, transposons or integrons, increasing the propagation of potential resistant pathogens. Substantial progress has already been made in elucidating the basic regulatory networks that endow bacteria with their extraordinary capacity to adapt to a diversity of lifestyles and external stress factors. So how will we face bacteria in the future?
Surveying Antimicrobial Resistance Approaches Issues And Challenges To Overcome
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Author : Gilberto Igrejas
language : en
Publisher: Frontiers Media SA
Release Date : 2017-03-29
Surveying Antimicrobial Resistance Approaches Issues And Challenges To Overcome written by Gilberto Igrejas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-29 with categories.
Why Antibiotic Resistance? The use of antibiotics in human and veterinary medicine may have consequences beyond their intended applications. The “One Health” concept recognizes that the health of humans is connected to the health of animals and the environment. Progress in molecular genetics is facilitating the rapid evaluation of the essentiality of these targets on a genomic scale. In 2015, a group of researchers established the International Conference on Antibiotic Resistance (IC2AR).The primary objective of this meeting is to bring together scientists involved in antibiotic resistance prevention and control. The IC2AR conducted its inaugural world congress in January 2015 at Caparica (Portugal). Antimicrobial resistance presents a significant challenge to scientists in the field of infectious diseases. The full knowledge of how antibiotics resistance is evolving and being transmitted between hosts in different ecosystems is taking on great importance. Necessary action includes research to define the scope of the problem including its various sources. This eBook comprises a series of original research and review articles dealing with the epidemiology of resistance in animal and zoonotic pathogens, mobile elements containing resistance genes, the omics of antimicrobial resistance, emerging antimicrobial resistance mechanisms, control of resistant infections, establishing antimicrobial use and resistance surveillance systems, and alternatives strategies to overcome the problem of antimicrobial resistance worldwide. Gilberto Igrejas, José Luis Capelo and Patrícia Poeta Scientific Committee of IC2AR, February 20th, 2017
Antimicrobial Resistance
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Author : World Health Organization
language : en
Publisher:
Release Date : 2014
Antimicrobial Resistance written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.
A New Paradigm For Environmental Chemistry And Toxicology
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Author : Guibin Jiang
language : en
Publisher: Springer
Release Date : 2019-08-09
A New Paradigm For Environmental Chemistry And Toxicology written by Guibin Jiang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-09 with Science categories.
This book provides comprehensive coverage of the theoretical developments and technological breakthroughs that have deepened our understanding of environmental pollution and human health, while also promoting a comprehensive strategy to address these problems. The respective chapters highlight groundbreaking concepts fueling the development of environmental chemistry and toxicology; revolutionary analytical and computational approaches providing novel insights into environmental health; and nature-inspired, innovative engineering solutions for tackling complex hazardous exposures. The book also features a forward-looking perspective on emerging environmental issues that call for new research and regulatory paradigms, laying the groundwork for future advances in the broad field of environmental chemistry and toxicology. Written by respected authorities in the field, A New Paradigm for Environmental Chemistry and Toxicology - From Concepts to Insights will offer an invaluable reference guide for concerned researchers and professional practitioners for years to come.
Antimicrobial Resistance
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Author : Yashwant Kumar
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-05-02
Antimicrobial Resistance written by Yashwant Kumar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-02 with Medical categories.
The discovery of antibiotics was considered a milestone in health sciences and became the mainstay of antimicrobial therapy to treat and control bacterial infections. However, its utility has subsequently become limited, due to the emergence and spread of antimicrobial resistance among different bacterial species, which has emerged as a global threat. The development and spread of antimicrobial resistance have been attributed to many factors, including indiscriminate use of antibiotics in the healthcare and livestock industries. The present scenario of antibiotic resistance urgently requires interventions in terms of development of newer antimicrobials, evaluation of alternative therapies, and formulation of stringent policies to curb indiscriminate use of antimicrobials. This book highlights the importance and development of antimicrobial resistance in zoonotic, environmental and food bacteria, including the significance of candidate alternative therapies.
Issues In Drug Management Toxicology Monitoring Resistance And Safety 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-05-01
Issues In Drug Management Toxicology Monitoring Resistance And Safety 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-01 with Medical categories.
Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Drug Testing and Analysis. The editors have built Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drug Testing and Analysis in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
New Strategies Combating Bacterial Infection
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Author : Iqbal Ahmad
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
New Strategies Combating Bacterial Infection written by Iqbal Ahmad and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.
Combating bacterial infections calls for a multidisciplinary approach and this is what is on offer here. Written by an experienced international team of researchers from various fields ranging from biotechnology to traditional medicine, the book provides complete and comprehensive coverage of topics relevant to new antibacterial drugs. This ready reference and handbook adopts a novel approach, focusing on combating multi-drug resistance in bacteria by developing antibacterials with new target sites, using new advances in drug discovery as well as natural products. Divided into three sections, the first describes the problem of drug resistance and the need for new drugs, while the second treats recent trends and new classes of drugs, including relevant developments in transcriptomics and proteomics leading to new antimicrobial drug discovery, and a new generation of antibiotics and non-antibiotics. The third section on natural products discusses the antibacterial action of phytocompounds, plant extracts, essential oils and honey as well as the role of probiotics in bacterial infections. Invaluable to students of medicine, pharmaceutical sciences, phytomedicine and microbiology and all those wanting to know about the possibilities and limitations of new antibacterial drugs. Furthermore, its coverage of plants and other natural products makes this relevant to the pharmaceutical and herbal industries.
Live Animal Trade Transport Magazine
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Author :
language : en
Publisher:
Release Date : 1997
Live Animal Trade Transport Magazine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Animal welfare categories.
Proceedings Of The 2nd Isessah Conference 2018
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Author : Bouda Vosough Ahmadi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-24
Proceedings Of The 2nd Isessah Conference 2018 written by Bouda Vosough Ahmadi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-24 with categories.
Antimicrobial Susceptibility Testing Protocols
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Author : Richard Schwalbe
language : en
Publisher: CRC Press
Release Date : 2007-05-22
Antimicrobial Susceptibility Testing Protocols written by Richard Schwalbe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-22 with Medical categories.
The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and