Synthetic Peptide Vaccine Models
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Synthetic Peptide Vaccine Models
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Author : Mesut Karahan
language : en
Publisher: CRC Press
Release Date : 2021-02-28
Synthetic Peptide Vaccine Models written by Mesut Karahan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-28 with Science categories.
A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy
Recombinant And Synthetic Vaccines
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Author : G. P. Talwar
language : en
Publisher: Springer
Release Date : 1994
Recombinant And Synthetic Vaccines written by G. P. Talwar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Carrier proteins categories.
Vaccines have historically been the most cost effective agents for the prevention of human and animal diseases. This volume gives a state-of-the-art description of the recombinant and synthetic vaccines for animal use as well as for hepatitis, HIV, measles, etc. Extensively covered are Malaria and vaccines for the control of fertility. Also described are new recombinant vaccines for anti-tuberculosis immunity and hantavirus hemmorrhagic fever, the development of genetic toxoids for pertussis and cholera and new technologies enabling the delivery of multiple doses of vaccines at a single contact point. This volume with contributions by numerous experts will be a valuable addition in this rapidly developing field.
Synthetic Vaccines
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-06
Synthetic Vaccines written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on synthetic vaccines. Contributions from leading authorities Informs and updates on all the latest developments in the field
Synthetic Peptides As Antigens
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Author : Ruth Porter
language : en
Publisher:
Release Date : 1986-06-04
Synthetic Peptides As Antigens written by Ruth Porter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-06-04 with Medical categories.
Synthetic peptides as antigens Ciba Foundation Symposium 119 Chairman: Gordon L. Ada 1986 Vaccination is a major means of combating infectious disease but no effective vaccine is available yet for many parasitic, viral and bacterial infections. A new approach consists of vaccines based on synthetic peptides rather than native parent antigens. The contributors to this symposium discuss the antigenicity and immunogenicity of synthetic peptides and their potential use in vaccines against malaria and other serious diseases. They consider the relationship between protein conformation and antigenicity, including the role of localized mobility and the conformational changes induced when peptides bind with immunoglobulin. A new method of synthesizing peptides able to mimic discontinuous epitopes is described. The symposium opens with a review of the regulation of immune responses in vivo. Carrier molecules such as PPD are being investigated; carrier choice plays a crucial role in the anti-hCG vaccine (based on a synthetic peptide) being tested as a means of birth control, and discussed here. Synthetic peptides are also of use as research tools, as described for the analysis of IgG sites responsible for autoantibody production in rheumatoid arthritis, and the localization of the c-myc oncoprotein in normal and transformed cells and in tumour masses. Other Ciba Foundation Symposia published by Pitman: No 114: Fibrosis Chairman: A.J. Bailey 1985 ISBN 0 272 79814 2 No 116: Growth factors in biology and medicine Chairman: Sir Michael Stoker 1985 ISBN 0 272 79818 5 No 118: Biochemistry of macrophages Chairman: Z.A. Cohn 1986 ISBN 0 272 79822 3
Synthetic Peptide Vaccine Models
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Author : Mesut Karahan
language : en
Publisher: CRC Press
Release Date : 2021-02-28
Synthetic Peptide Vaccine Models written by Mesut Karahan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-28 with Science categories.
A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy
Current And Future Aspects Of Nanomedicine
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Author : Islam Khalil
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-05-06
Current And Future Aspects Of Nanomedicine written by Islam Khalil and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-06 with Technology & Engineering categories.
Nanomedicine refers to the use of nanotechnological applications in biomedical fields such as therapeutics, diagnostics, monitoring, visualization, tissue engineering and even surgery. This book presents recent updates in the nanomedicine market and discusses several aspects of drug delivery and tissue regeneration using different platforms and devices.
Pharmaceutical Biotechnology
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Author : Daan J. A. Crommelin
language : en
Publisher: CRC Press
Release Date : 2002-11-14
Pharmaceutical Biotechnology written by Daan J. A. Crommelin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-14 with Medical categories.
The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.
Peptide Therapeutics
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Author : Ved Srivastava
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-08-28
Peptide Therapeutics written by Ved Srivastava and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-28 with Science categories.
Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal policy or guidelines on CMC for peptide-based drugs. Regulators use a risk-based approach, reviewing applications on a case-by-case basis. Peptide Therapeutics: Strategy and Tactics for Chemistry, Manufacturing, and Controls covers efficient manufacturing of peptide drug substances, a review of the process for submitting applications to the regulatory authority for drug approval, a holistic approach for quality attributes and quality control from a regulatory perspective, emerging analytical tools for the characterisation of impurities, and the assessment of stability. This book is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about CMC, and facilitating development and manufacture of peptide-based drugs.
Immunoinformatics
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Author : Namrata Tomar
language : en
Publisher: Humana
Release Date : 2021-03-26
Immunoinformatics written by Namrata Tomar and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Medical categories.
This book covers a wide range of diverse immunoinformatics research topics, involving tools and databases of potential epitope prediction, HLA gene analysis, MHC characterizing, in silico vaccine design, mathematical modeling of host-pathogen interactions, and network analysis of immune system data. In that way, this fully updated volume explores the enormous value of computational tools and models in immunology research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key insights and detailed implementation advice to encourage successful results in the lab. Authoritative and practical, Immunoinformatics, Third Edition serves as an ideal guide for scientists working at the intersection of bioinformatics, mathematical modelling, and statistics for the study of immune systems biology.
Peptide Antibodies
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Author : Gunnar Houen
language : en
Publisher: Humana
Release Date : 2015-10-02
Peptide Antibodies written by Gunnar Houen and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-02 with Medical categories.
This extensive volume covers basic and advanced aspects of peptide antibody production, characterization and uses. Although peptide antibodies have been available for many years, they continue to be a field of active research and method development. For example, peptide antibodies which are dependent on specific posttranslational modifications are of great interest, such as phosphorylation, citrullination and others, while different forms of recombinant peptide antibodies are gaining interest, notably nanobodies, single chain antibodies, TCR-like antibodies, among others. Within this volume, those areas are covered, as well as several technical and scientific advances: solid phase peptide synthesis, peptide carrier conjugation and immunization, genomics, transcriptomics, proteomics and elucidation of the molecular basis of antigen presentation and recognition by dendritic cells, macrophages, B cells and T cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Peptide Antibodies: Methods and Protocols serves as an ideal reference for researchers exploring this vital and expansive area of study.