Systemic Regulation Of Organ Homeostasis And Implications Of Hormones And Immunity Volume Ii
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Systemic Regulation Of Organ Homeostasis And Implications Of Hormones And Immunity Volume Ii
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Author : Vijaya Kumar Pidugu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-20
Systemic Regulation Of Organ Homeostasis And Implications Of Hormones And Immunity Volume Ii written by Vijaya Kumar Pidugu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-20 with Medical categories.
Systemic Regulation Of Organ Homeostasis And Implications Of Hormones And Immunity
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Author : Premendu Prakash Mathur
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-29
Systemic Regulation Of Organ Homeostasis And Implications Of Hormones And Immunity written by Premendu Prakash Mathur and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-29 with Science categories.
Sensing The Environment Regulation Of Local And Global Homeostasis By The Skin S Neuroendocrine System
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Author : Andrzej T. Slominski
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-02
Sensing The Environment Regulation Of Local And Global Homeostasis By The Skin S Neuroendocrine System written by Andrzej T. Slominski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-02 with Medical categories.
The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other physical and chemical agents. Examples of local biologically active products are cytokines, biogenic amines (catecholamines, histamine, serotonin and N-acetyl-serotonin), melatonin, acetylocholine, neuropeptides including pituitary (proopiomelanocortin-derived ACTH, b-endorphin or MSH peptides, thyroid stimulating hormone) and hypothalamic (corticotropin-releasing factor and related urocortins, thyroid-releasing hormone) hormones, as well as enkephalins and dynorphins, thyroid hormones, steroids (glucocorticoids, mineralocorticoids, sex hormones, 7-δ steroids), secosteroids, opioids and endocannabinoids. The production of these molecules is hierarchical, organized along the algorithms of classical neuroendocrine axes such as the hypothalamic pituitary adrenal axis (HPA), hypothalamic-thyroid axis (HPT), serotoninergic, melatoninergic, catecholaminergic, cholinergic, steroid/secosteroidogenic, opioid and endocannabinoid systems. Disruptions of these axes or of communication between them may lead to skin and/or systemic diseases. These local neuroendocrine networks also serve to limit the effect of noxious environmental agents to preserve local and consequently global homeostasis. Moreover, the skin-derived factors/systems can also activate cutaneous nerve endings to alert the brain to changes in the epidermal or dermal environments, or alternatively to activate other coordinating centers by direct (spinal cord) neurotransmission without brain involvement. Furthermore, rapid and reciprocal communications between epidermal and dermal and adnexal compartments are also mediated by neurotransmission including antidromic modes of conduction. Lastly, skin cells and the skin as an organ coordinate and/or regulate not only peripheral but also global homeostasis.
Novel Aspects Of Neurotransmitters
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Author : Zhi-Gang Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10
Novel Aspects Of Neurotransmitters written by Zhi-Gang Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Science categories.
Neuro Immune Interactions In Inflammation And Autoimmunity
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Author : Valentin A. Pavlov
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-24
Neuro Immune Interactions In Inflammation And Autoimmunity written by Valentin A. Pavlov and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-24 with categories.
The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal integrity and brain function. Recent studies have characterized neural pathways communicating peripheral inflammatory signals to the CNS, and brain- and spinal cord-derived circuitries controlling various innate and adaptive immune responses and inflammation. A prototypical neural reflex circuit that regulates immunity and inflammation is the vagus nerve-based “inflammatory reflex”. Ongoing research has revealed cellular and molecular mechanisms underlying these neural circuits and indicated new therapeutic approaches in inflammatory and autoimmune disorders. Pharmacological and bioelectronic modulation of neural circuitry has been successfully explored in preclinical settings of sepsis, arthritis, inflammatory bowel disease, obesity-driven disorders, diabetes and other diseases. These studies paved the way to successful clinical trials with bioelectronic neuronal modulation in rheumatoid arthritis and inflammatory bowel disease. Dysregulated release of cytokines and other inflammatory molecules may have a severe impact on brain function. Brain inflammation (neuroinflammation), imbalances in brain neuronal integrity and neurotransmitter systems, and cognitive impairment are characteristic features of post-operative conditions, sepsis, liver diseases, diabetes and other disorders characterized by immune and metabolic dysregulation. Derangements in cytokine release also play a pivotal role in depression. Characteristic brain reactive antibodies in autoimmune conditions, including systemic lupus erythematosus and neuromyelitis optica, significantly contribute to brain pathology and cognitive impairment. These studies, and the simultaneous characterization of neuro-protective cytokines, identified new therapeutic approaches for treating neurological complications in inflammatory and autoimmune disorders. This Frontiers Research Topic is a forum for publishing research findings and methodological and conceptual advances at the intersection of immunology and neuroscience. We hope that presenting new insight into bi-directional neuro-immune communication in inflammation and autoimmunity will foster further collaborations and facilitate the development of new efficient therapeutic strategies.
Pathophysiology E Book
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Author : Jacquelyn L. Banasik
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-12-21
Pathophysiology E Book written by Jacquelyn L. Banasik and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-21 with Medical categories.
A clear, comprehensive introduction to disease, Pathophysiology, 5th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of disorders. Units are organized by body system, and each begins with an illustrated review of anatomy and normal physiology. A discussion then follows on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading educators Lee-Ellen Copstead and Jacquelyn Banasik, Pathophysiology simplifies a rigorous subject with practical learning resources and includes coverage of the latest scientific findings and relevant research 900 full-color illustrations clarify complex pathophysiological concepts. Easy-to-read style includes many tables, boxes, and figures to highlight and simplify content. Key Questions at the beginning of each chapter highlight key objectives and help you develop and use critical thinking skills. Key Points boxes focus on the most important information. Geriatric Considerations boxes analyze the age-related changes associated with a specific body system. A chapter summary gives you a quick wrap-up of the key content in each chapter. NEW! Pediatric Considerations boxes with accompanying flow charts describe conditions and changes specific to young children. NEW! Updated content includes the latest information on new treatment advances, the relationship between stress and inflammation to cardiovascular disease, and much more throughout the text. NEW! Global Health Considerations tables include information on HIV/AIDS and depression/anxiety in women.
Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics E Book
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Author : Nader Rifai
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-09-02
Tietz Fundamentals Of Clinical Chemistry And Molecular Diagnostics E Book written by Nader Rifai and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Medical categories.
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Laboratory Technology**Master clinical lab testing skills with the condensed version of the Tietz Textbook! Designed for use by CLS students, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 9th Edition provides a streamlined guide to the clinical chemistry knowledge you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry educator Nader Rifai, this textbook shows how to select and perform diagnostic lab tests, and how to accurately evaluate results. - Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. - Authoritative, foundational content mirrors that in the Tietz "bible" of laboratory medicine but in a more concise way. - Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. - Clinical cases from the Coakley Collection demonstrate how concepts from the text are applied in real-life scenarios. - More than 400 illustrations and easy-to-read summary tables help you better understand and remember key concepts. - Learning objectives, key words with definitions, and review questions are included in each chapter to make learning easier. - NEW! Updated content throughout the text keeps you up to date on the latest techniques, instrumentation, and technologies. - NEW! Additional questions are added to each chapter for subject reinforcement. - NEW! Access to Adaptive Learning courses in clinical chemistry and molecular diagnostics is provided on the Evolve website.
Psychoneuroimmunology
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2025-01-16
Psychoneuroimmunology written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-16 with Medical categories.
This book seeks to represent the main concepts and theories related to psychoneuroimmunology with the aim of their application in clinical settings and formation of novel theories to further elucidate the mutual connection of the psyche and the physiology of humans' body. Psychoneuroimmunology, as an integration of popular research fields such as psychology, immunology, neurology, and neuroscience, is a perfect example of interdisciplinary and transdisciplinary studies that could potentially result in developing alternative diagnostic tools and treatment strategies besides facilitating the understanding of the pathophysiology of some conditions that might not properly be understood with a single point of view. Considering the stressful lifestyle and the high prevalence of neuropsychiatric, metabolic, and immune-related disorders, psychoneuroimmunology could be the path to the management of these conditions and reduction of the burden of the diseases
The Physiological Regulation Of Energy Metabolism In Insects
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Author : Bin Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-23
The Physiological Regulation Of Energy Metabolism In Insects written by Bin Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-23 with Science categories.
Master Medicine Physiology E Book
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Author : J. Graham McGeown
language : en
Publisher: Elsevier Health Sciences
Release Date : 2007-02-19
Master Medicine Physiology E Book written by J. Graham McGeown and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-19 with Medical categories.
This title is part of a series of books that reflects the trend towards a core curriculum and self-directed learning. The content is restricted to the 'must know' core information presented in a synoptic style. The diagrams that support the text are in a style that the reader can remember and reproduce in examinations. Each chapter ends with a selection of self-assessment material and full explanatory answers. These consolidate and expand on the chapter contents. - Concise synoptic (not telegraphic text). - Appropriate self-assessment material. - Only covers core, so student knows the whole book is essential. - Includes key objectives. - Contains simple and memorable diagrams for reproduction in exams. - Ideal for learning as well as examination review, specifically trying to stimulate the student into assessing his/her own knowledge. - The books in the series both complement other available major texts, but also contain enough material to stand in the own right. - Provides examination practice. - Part of co-ordinated series.